Optibiotix Health Share Discussion Threads

[kreature] 12/6/2021 22:37

‘ Be aware that a high intake of prebiotic foods, especially if introduced suddenly, can increase gas production (flatulence) and bloating.’

I mean that

[kreature] 12/6/2021 22:35

‘ Whether you believe the health claims or think they are yet another snake oil scam, they make up a multi-billion dollar industry that is evolving in tandem with quickly emerging research.’

Why is that not written clearly on the box ?

[manc10] 12/6/2021 22:33

From butterflies in the stomach to going with your ‘gut instinct’, the gut microbiome and its links with the human brain has been a popular research topic in scientific circles. Growing evidence in this area has shown that the gut microbiome and brain communicate in a ‘bidirectional manner’, influencing each other’s functions.

As a result, we now know that several systems work synergistically to ensure the human body continues to function correctly. This comprises of the central nervous system (CNS), the enteric nervous system (ENS), the endocrine, immune and autonomic nervous system (ANS). When the ENS and CNS systems communicate, it’s called the ‘gut-brain axis’, where complex pathways between cognitive and emotional areas of the brain link with the endocrine and immune systems, alongside the ANS. So, when we feel ‘butterflies in our stomach’, stress and anxiety, the communication between the ENS, CNS and ANS gets disrupted and these feelings become amplified, shifting the overall state of balance of the gut-brain axis.

Evolving science and the gut-brain axis

Scientists have also discovered that one of the most important connections in the human body is the vagus nerve, which is an essential part of the gut-brain axis. It consists of two bundles of neurons that run down each side of the body, from the brain to the abdomen and intestinal tract. As a result, it’s now understood that the stimulation of the vagus nerve can be triggered by signals from specialized cells and bacteria in the gut microbiome.

Recent studies, for example, have demonstrated that when mice lack a microbiome they experience anxiety- and depression-like behaviours. Moreover, researchers have discovered that patients with neurodegenerative diseases such as Parkinson’s and Alzheimer’s Disease are more likely to have an altered microbiome. Evidence like this suggests that the gut microbiome and the bacterial species it is made up from, including Firmicutes, Bacteroides and more, not only influence human behaviour but may affect the pathophysiology of mental illness and neurodegenerative diseases.

The role of prebiotics and probiotics

When it comes to matters of the gut-brain axis, both prebiotics and probiotics have been found to play a significant role. The latest research suggests that probiotics, for example, may have the ability to reduce the production of inflammatory chemicals like cytokines in inflammatory bowel disease. In addition, they may also help direct the action of tryptophan – a chemical that’s noted for its importance in the gut-brain axis in relation to psychiatric disorders.

In a 2018 study, the probiotic strain Lactobacillus plantarum 299v was found to decrease kynurenine concentration – a metabolite of tryptophan that is made in response to immune activation – and improved cognitive function in patients with major depression. While in a randomised, double-blind and placebo-controlled trial, petrochemical workers who consumed a probiotic yoghurt or a multi-species probiotic capsule for six weeks also demonstrated improved mental health, when measured through a depression, anxiety and stress scale.

Interestingly when probiotics are taken in combination with prebiotics, they may help to ease mood disorders. As prebiotics help to feed the good bacteria inside the gut, researchers have found that they could improve sleep and boost stress resilience. For instance, in a new study by the North American Menopause Society, scientists found that a higher dietary fibre intake is linked to a lower risk of depression in pre-menopausal women.

The latest OptiBiotix research

At OptiBiotix, we are fascinated with the latest scientific studies into how microbiome modulation technology can influence mood and mental health. In our latest study conducted by the University of Roehampton, we demonstrated that our patented weight management ingredient, SlimBiome®, greatly improved mood and gut microbiome composition. When participants ingested 9g per day of our multi-award-winning ingredient, it resulted in a statistically significant improvement in mood after four weeks (p = 0.0026).

Our patented probiotic strain, Lactobacillus plantarum LPLDL® has also achieved anecdotal evidence from users that it can improve mood. In fact, we are currently funding new research into how our probiotic strain, alongside SlimBiome, can improve sleep, stress and anxiety.

For pharmaceutical, food and drink and supplement brands and manufacturers that are looking to expand their commercial portfolio with mood-boosting prebiotic and probiotic ingredients, OptiBiotix could have the solution. While scientific evidence is pivotal to the next steps we take as market leaders in microbiome modulation, it is also just as important to seek new understanding on the connection between the gut microbiome and the brain.

[sentiment riles] 12/6/2021 22:28

That Hurt the Brain even more

[kreature] 12/6/2021 22:24

Excellent read manc, thank you

‘ Whether you believe the health claims or think they are yet another snake oil scam........’

Why do they say ‘yet another’? Are they usually a scam or something? I’m upset now...

[kreature] 12/6/2021 22:22

Senti filtered and reported .....That question hurts the brain

[sentiment riles] 12/6/2021 21:36

Why are opti happy to recognise forward sales but only tell us in retrospect about forward sells?

[manc10] 12/6/2021 20:51

1. Microorganisms in the gut outnumber human cells in the gut by 10 to 1.

Scientists have estimated that the number of microorganisms that live in the intestine outweighs human cells at a ratio of 10 to 1. The intestine has a community of microbes or "microbiota" of between 1,000 to 1,500 bacterial species that changes and evolves over time. Optimally, the gut is both diverse and abundant in microbes, with a balance of five types of bacteria: Firmicutes (80 percent), Bacteroidetes (17 percent), Actinobacteria (3 percent), Proteobacteria (1 percent), and Verrucomicrobioa (0.1 percent). When the gut microbiome is healthily balanced, it is in a state of "eubiosis."

2. Your gut is called the "second brain" because it has such an important role in brain-based disorders like anxiety and depression.

The gut has its own nervous system called the "enteric nervous system" which communicates in the same way as your brain and central nervous system—with neurons and neurotransmitters. Every microorganism has a different effect on the enteric nervous system. The vagus nerve, which is influenced by stress, is also connected with the intestinal cell system—this has led researchers to believe it may be an important link between the brain and gut or "brain-gut axis." Certain types of gut bacteria produce neurotransmitters like serotonin, dopamine, norepinephrine and GABA which can enter the bloodstream and affect brain function.

3. Changing what you eat can improve your gut microbiome in as little as 3 days.

What you eat plays a very important role in maintaining and developing a healthy and balanced gut microbiome. The microbiome will change according to what you eat in as little as 3 days. When the composition and diversity of the gut microbiome becomes imbalanced, the problem is called gut "dysbiosis." Restrictive fad diets can reduce the diversity of the bacteria living in the gut. Intermittent fasting can inadvertently lead to the selective overgrowth of certain species of bacteria.

[manc10] 12/6/2021 20:50

Sugars like table sugar and lactose (milk sugar) are quickly absorbed in the upper part of the small intestine, but more complex carbohydrates like starches and fibers are not as easily digested and may travel lower to the large intestine. There, the microbiota help to break down these compounds with their digestive enzymes. The fermentation of indigestible fibers causes the production of short chain fatty acids (SCFA) that can be used by the body as a nutrient source but also play an important role in muscle function and possibly the prevention of chronic diseases, including certain cancers and bowel disorders. Clinical studies have shown that SCFA may be useful in the treatment of ulcerative colitis, Crohn’s disease, and antibiotic-associated diarrhea. [2]

The microbiota of a healthy person will also provide protection from pathogenic organisms that enter the body such as through drinking or eating contaminated water or food.

Large families of bacteria found in the human gut include Prevotella, Ruminococcus, Bacteroides, and Firmicutes. [4] In the colon, a low oxygen environment, you will find the anaerobic bacteria Peptostreptococcus, Bifidobacterium, Lactobacillus, and Clostridium. [4] These microbes are believed to prevent the overgrowth of harmful bacteria by competing for nutrients and attachment sites to the mucus membranes of the gut, a major site of immune activity and production of antimicrobial proteins. [5,6]

The role of probiotics
If microbiota are so vital to our health, how can we ensure that we have enough or the right types? You may be familiar with probiotics or perhaps already using them. These are either foods that naturally contain microbiota, or supplement pills that contain live active bacteria—advertised to promote digestive health. Probiotic supplement sales exceeded $35 billion in 2015, with a projected increase to $65 billion by 2024. Whether you believe the health claims or think they are yet another snake oil scam, they make up a multi-billion dollar industry that is evolving in tandem with quickly emerging research.

Dr. Allan Walker, Professor of Nutrition at the Harvard Chan School of Public Health and Harvard Medical School, believes that although published research is conflicting, there are specific situations where probiotic supplements may be helpful. “Probiotics can be most effective at both ends of the age spectrum, because that’s when your microbes aren’t as robust as they normally are,” Walker explains. “You can influence this huge bacterial colonization process more effectively with probiotics during these periods.” He also notes situations of stress to the body where probiotics may be helpful, such as reducing severity of diarrhea after exposure to pathogens, or replenishing normal bacteria in the intestine after a patient uses antibiotics. Still, Walker emphasizes that “these are all circumstances where there’s a disruption of balance within the intestine. If you’re dealing with a healthy adult or older child who isn’t on antibiotics, I don’t think giving a probiotic is going to be that effective in generally helping their health.”

[sentiment riles] 12/6/2021 20:29

“ one reason a company may DEMAT a large stock holding, is for fast selling purposes”

[kreature] 12/6/2021 20:05

A bit tired actually, so I think I also broke the microbiomes responsible for staying awake. Happy to do a study to prove that, then who do I sue ?

[kreature] 12/6/2021 20:03

fairly sure I broke the microbiomes in charge of pain control

[kreature] 12/6/2021 20:02

I fell on a hole in the pavement and hurt my microbiomes. Who can I sue for that?

[sentiment riles] 12/6/2021 20:00

madoff microbiome fund

[woollworth] 12/6/2021 19:52

manc1011 Jun '21 - 21:05 - 13199 of 13200

wokeworth stop getting emotional with 1p drops you must have everything you own in opti a stock you chose to invest in yourself if the share price was 122 again would you still be crying answer no my advice is put your money in a fund and take 9% a year.

If only...

[sentiment riles] 12/6/2021 18:36

Official now. Great news

Maybe that doctor can treat Aim companies

[sentiment riles] 12/6/2021 18:29

Euros tweets too

Hard to know what’s fake and real though

[sentiment riles] 12/6/2021 18:27

BeinSPORTS say he ok or stable

Not sure how reliable that is

Hopefully

[sentiment riles] 12/6/2021 18:15

Proper quality

I’m just wondering why it’s called AIM really