Immupharma Share Discussion Threads

[brad44] 10/2/2022 13:12

nooby was betting both ways on the phase 3 outcome last time from memory. he holds shares (unless he isnt telling the truth) and also holds short positions, so you have to bear this in mind when you listen to him.

to me IMM has alot more going for it than just Lup, I'm not a big fan of Tim, but he now does have some skin in the game. its the link up with Avion that i believe will assist them this time. and time will tell..

[kilgallp] 10/2/2022 12:46

Fair enough Nobby, appreciate the response.

[nobbygnome] 10/2/2022 10:54

Why do people always ask that question? I never get it.....

I'm not going to go into my long history with Lupuzor and IMM but suffice to say I know an awful lot about this drug. I think s_k would back this up. My strong opinion is that what has happened here is a tragedy; there is a half decent drug trying to get out but sadly due to mismanagement over a long period, the benefits of the drugs have not been realised.

See it as a crusade....

[kilgallp] 10/2/2022 10:45

Nobby, I've been in here for years but don't post very often. In fact, this might be my first post on this thread. But I'm intrigued, you query Eva's enthusiasm, but in all the time I've followed this thread, I don't think I've ever heard you post positively. In an earlier post you said, (I'm not quoting your words, but in essence),
'Every time I watch Tim McCarthy speak, I expect to see his knows grow!'
As far as I can see, you have no faith in the product, you don't trust the management, so why are you here?

[lord loads of lolly] 10/2/2022 09:34

thordon - interesting that Avon (cosmetics & beauty company) have joined Avion Pharmaceuticals in backing IMM. Shurely shome mistake.

[thordon] 09/2/2022 22:34

It may be multiple doses per day , anyway will not know till the experiment is over.
Hence why as with other company's have placed my investment at £4k at 6.7p.
There are others much underwater so its a risk taken with massive upside , in any case if fails will be one of a few that have not done well and will sleep good whichever.
It's why the market has not acted positive to the news ; old news can haunt you.

My main reason was as said before the parent company of Avon investing £1 million in IMM that was my trigger point.

[nobbygnome] 09/2/2022 22:14

But why do the FDA want to know 'how quick (it) disappears from the body'? It is the crucial question which we don't have the answer to sadly.

Oh and I would love someone to explain to me how a lower dose can be better when the drug disappears in a few hours. Hmmmmm an intriguing conundrum......

[thordon] 09/2/2022 22:02

Nobbygnome always value your words - as a precaution went over the last 3 years RNS.
My understanding is that at a high dose is less effective but at a lower dose does brings positive results.
So the latest is on fit humans to test on , to ensure one no side effects and how quick disappears from the body.
On that note noticed the parent company of Avon investing £1 million in IMM , which indicates inside information.
Have to say the history of IMM is not good and understand the worry.

[nobbygnome] 09/2/2022 17:42

Just belatedly watched the Proactive interview. Why is it that I always expect McCarthy's nose to start growing as he speaks.....

As usual the key question wasn't answered. Why did the FDA ask for a PK study if as McCarthy claims, they've accepted the trial protocol? They must have a concern about the PK and as previously discussed they can't really use another dose so if there is any issues, the phase III could well be a bust. For me it's very disingenuous for the company not to have elucidated this point in any of their communications!

[eva_1989] 09/2/2022 14:21

lord - it's okay.

My money my choice...

You don't need to worry about me.. You can sleep peacefully at night.. Thank you.

[lord loads of lolly] 09/2/2022 11:48

eva_1989 - "with Mcap of 20Million - what could go wrong?". I'd say an Mcap of anything less than £20M is what could go wrong.

[eva_1989] 09/2/2022 11:21

Nobby - with Mcap of 20Million - what could go wrong ?

One decent news and we know how IMM shoot up... i'm happy to wait.

guess after March, IMM will get response latest by May/June - so happy to wait for 4-5 months..

And i don't trust IMM management but I do trust Avion...

[nobbygnome] 08/2/2022 22:18

I really don't understand your excessive enthusiasm for IMM Eva. You are taking such a risk considering there is a real possibility the PK study may produce concerning results for the FDA. And we all know the management is not to be trusted here....

Each to their own though....

[eva_1989] 08/2/2022 17:27

Thanks 1U -

Really depressed share price Guess PK approval and this share price will be history forever. Just couple of months and we will find out!

Btw my both orders shows sell

8-Feb-22 15:30:15 6.6887 140,000 Sell* 9,364 O
08-Feb-22 15:22:08 6.6407 100,000 Sell* 6,641 O
0

[1ultimate] 08/2/2022 16:34

Hi Eva, I hope you are well!! This is too cheap at the moment…crazy cheap imho dyor

[eva_1989] 08/2/2022 16:29

Goodness me!

[lord loads of lolly] 08/2/2022 16:26

eva_1989 - here's one I made (up) earlier:
Order reference
179736721
Investment name
Immupharma Plc
Investment code
IMM.LN
Date order placed
08/02/2022
Time order placed
16:25:28
Settlement date
11/02/2022
Number of shares or units
1600000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000
Share or unit price
6.57p
Consideration
£1,948,478,869
Transaction charge
£20.00
Total charges
£20.00

[eva_1989] 08/2/2022 15:31

Okay another one gone through

Order reference
175602021
Investment name
Immupharma Plc
Investment code
IMM.LN
Date order placed
08/02/2022
Time order placed
15:30:19
Settlement date
11/02/2022
Number of shares or units
140000
Share or unit price
6.69p
Consideration
£9,364.18
Transaction charge
£20.00
Total charges
£20.00

[eva_1989] 08/2/2022 15:24

Ok who is buying me with today ?/

Max they allow me is this...

Order reference
175601995
Investment name
Immupharma Plc
Investment code
IMM.LN
Date order placed
08/02/2022
Time order placed
15:22:12
Settlement date
11/02/2022
Number of shares or units
100000
Share or unit price
6.64p
Consideration
£6,640.70
Transaction charge
£20.00
Total charges
£20.00



Total consideration
£6,660.70

[colsmith] 08/2/2022 10:35

Nobby re your "As for why the FDA are asking now is an open question."

Its probably the FDA being in the pockets of vested interest; if so a nice delay tactic and of course the Covid stuff was passed at F1 speed not using the standard approach. Seems to me that either all the testing and years and cost taken on any " normal product" is either snake oil or needed, so why the F1 speed and P140 in the go cart?

[nobbygnome] 08/2/2022 09:26

Good point s_k; that would be a logical approach

[sicilian_kan] 08/2/2022 09:18

I suspect that if the PK study pans out as nobby expects, then Immupharma will move onto the second generation Lupuzor which will have longer patent life too:

From 18 Nov 21 RNS:

"-- P140 - Second generation
Our pre-clinical team in Bordeaux, 'ImmuPharma Biotech' headed up by Dr Sebastien Goudreau, has commenced work to develop a pharmacologically improved version of P140, a second generation product that aims to further strengthen the IP position and provide therapies with different improved administration modalities, yet still maintaining P140 as the active moiety."