Gsk Share Discussion Threads

[netcurtains] 17/2/2023 10:24

TraderMichael: Of course, just stating stats.... The RISE is continuing... Accelerating if anything.
Zantac was a drug of the 1970s - most of those people were old even then.
So rise is not linked to Zantac .

[tradermichael] 17/2/2023 09:46

net (31603 )- very dangerous to make that assertion! Most cancers take years to develop.

[mj19] 17/2/2023 09:43

Courts cases are not judged on emotions it should be factual information with data as proof ?

[netcurtains] 17/2/2023 09:39

GLAXO reported 40% less sales on Zantac in 1998 (when its licence ran out)... And declining fast.



Also exactly around that time (from 1990s) cancer rates ROSE DRAMATICALLY. So if you looked at casual data, if anything, Glaxo's Zantac would appear to have prevented cancer.

[alibizzle] 17/2/2023 09:11

Is there any news on whether the judge is going to allow the key witness to give testimony on Feb 27 yet

[tradermichael] 17/2/2023 09:03

The impurity is present in a wide number of entities - NDMA is a type of chemical found in tobacco products and tobacco smoke. Nitrosamines are also found in many foods, including fish, beer, fried foods, and meats. To allege that these cancers were caused solely by a trace impurity in Ranitidine when exposure to the chemical could have routinely been experienced (and possibly over a lifetime and in higher amounts) is flawed and therefore not evidential.

[netcurtains] 17/2/2023 08:57

Since the drug was removed from the shelves, are more or less people getting cancer in the USA?


The dramatic RISE in cancer rates have occurred AFTER zantac was withdrawn.

[netcurtains] 17/2/2023 08:54

You would think it would be impossible to prove - eg if FDA say its OK then how can you get beyond "not proven".....
But who knows.

[mj19] 17/2/2023 08:48

Be very difficult to prove... in my opinion you would need scientific evidence...

[netcurtains] 17/2/2023 08:22

Do we know why its rising strongly this morning?
Did the case look sound from GSK point of view?

Or is it on the good drug news item?

[mj19] 17/2/2023 08:05

GSK: Lawyers for a man who alleges he developed bladder cancer after taking GSK Plc's heartburn drug Zantac urged a California judge to allow expert testimony linking the drug to the illness at an upcoming trial.

[spoole5] 16/2/2023 21:09

https://www.bloomberg.com/news/features/2023-02-15/zantac-cancer-risk-data-was-kept-quiet-by-manufacturer-glaxo-for-40-years?utm_source=website&utm_medium=share&utm_campaign=twitter?sref=Umh7YXqB#xj4y7vzkg&in_source=embedded-checkout

[tradermichael] 16/2/2023 16:59

Excellent result:

Landmark New England Journal of Medicine publication reinforces potential of GSK's respiratory syncytial virus older adult vaccine candidate

-- First peer-reviewed publication of phase III respiratory syncytial virus vaccine data in older adults, including those with comorbidities who are most at risk

-- Expert perspective recognises a new era in vaccine design based on progress in respiratory syncytial virus research

-- Vaccine on track to become available in 2023 pending regulatory decisions in the US, EU, and other countries

GSK plc (LSE/NYSE: GSK) today announced the publication of positive phase III trial results for its respiratory syncytial virus (RSV) older adult vaccine candidate in the New England Journal of Medicine . The publication summarises the pivotal efficacy data ( previously presented at IDWeek 2022), showing the vaccine candidate met the primary endpoint of vaccine efficacy against RSV-lower respiratory tract disease (LRTD) in adults aged 60 years and above, with a favourable safety profile. In addition, positive vaccine efficacy was observed in participants with comorbidities of interest who are at increased risk of severe outcomes.

RSV is one of the major infectious diseases without a vaccine or specific treatment available for older adults. The accompanying New England Journal of Medicine expert perspective article recognises the significant progress that has been made in RSV vaccine design. GSK is the first company to publish positive peer-reviewed phase III data for an RSV older adult vaccine candidate.

Tony Wood, Chief Scientific Officer, GSK, said: "Our ambition is to protect the many older adults at risk from RSV disease, including those with underlying health conditions, who account for the majority of severe RSV outcomes. We are delighted to publish these exceptional data in the New England Journal of Medicine . We look forward to making the vaccine available as quickly as possible, pending regulatory decisions, and sharing more data from our ongoing clinical development programme as we work to get ahead of this potentially debilitating virus."

[bothdavis] 15/2/2023 17:08

All medicines have some sort of side effect....look at the befuddling piece of folded paper with each prescription! Do we read it, with the small typeface? Course we don't!

It is a balancing act betwen what afflicts us and our need to be cured or prevented from getting worse........

[drk1] 15/2/2023 17:06

Well, after listening to the Bloomberg podcast in full, I'd say that it is definitely looking more positive than negative for GSK! Near impossible to prove either a direct or indirect link.

[netcurtains] 15/2/2023 15:04

the price is up significantly since beginning of Feb.
I think the implication is some people think
GSK will win the case soon.

[max euwe] 15/2/2023 14:59

These mRNA shots are causing cancer in millions, but that's all shoved under the carpet.

[tradermichael] 15/2/2023 14:03

" ......If you receive queries about this issue from patients, advise them not to stop taking their medication as the health risk of discontinuing the medicine is higher than the potential risk presented by the contaminant......."

[netcurtains] 15/2/2023 14:03

All the sources seem a bit dodgy to me.
Cheers Net.

However if these dodgy sources do their stuff well and GSK wins or gets a dismissal then this share will go ballistic.

It depends on how many people believe or hedged their bets based on dodgy news.

[zho] 15/2/2023 13:39

Thousands Claim A Blockbuster Drug Gave Them Cancer

[netcurtains] 15/2/2023 13:22

Geck: Do you have a better source than that? Thanks.

[geckotheglorious] 15/2/2023 12:59

"GSK kept quiet about cancer risks of heartburn drug for 40 years – Bloomberg"

GSK (NYSE:GSK) American Depository Shares lost ~2% pre-market Wednesday after a new report from Bloomberg Businessweek claimed that the British drugmaker chose to keep quiet on the cancer risks of the recalled heartburn medication Zantac.
Zantac, also known as ranitidine, was pulled from the U.S. market in 2020 amid concerns over the unacceptable levels of potential human carcinogen, N-nitrosodimethylamine (NDMA).
Since then, the makers of generic versions of Zantac, including Sanofi (SNY) (OTCPK:SNYNF), GSK (GSK), Pfizer (PFE), and Boehringer Ingelheim GmbH, have faced thousands of lawsuits for failure to adequately warn health risks of the antacid.
Citing court filings, studies, FDA transcripts, and new drug applications obtained through the Freedom of Information Act requests, Bloomberg said that the FDA considered the cancer risks when greenlighting the medication, but GSK (GSK) withheld key study data.
Even worse, the company, then known as GlaxoSmithKline (GSK), supported flawed studies to minimize the concerns and opted against using methods such as routine transport and storage that would have lessened the impact.
In one instance, just after filing for marketing approval in 1982, John Padfield, the head of pharmaceutical development of GSK (GSK), warned that the tablet version of ranitidine had to be kept chilled from importation to the warehouse storage.
After Padfield argued in March that not doing so would be “a very dangerous thing,” the company executives wrote several months later that “refrigeration of the injection would not be acceptable to Glaxo marketing.”

[netcurtains] 15/2/2023 12:13

I think with covid claims round the corner it would be wise of the legal system to throw out claims unless they have strong concrete evidence otherwise heaven help AZN and pfizer investors

[netcurtains] 15/2/2023 12:09

This is probably the last state of any importance.