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[badtime] 20/3/2019 13:08

Sp has been pretty stable last few weeks which has quietened a couple of posters

[jadeticl3] 20/3/2019 10:44

TM, thanks for this information. Maybe, just maybe, it is starting to awake this morning!

[tradermichael] 20/3/2019 09:59

I think that GSK is sitting on a goldmine of new immuno-oncology drugs with the acquisition of Tesaro, as the results of clinical trials start to filter through during 2019. GSK recognised this in the massive investment made through the purchase of this asset. The market has yet to wake up to the value of this opportunity.

[tradermichael] 20/3/2019 09:48

For information, there is a former tie-up between Tesaro and a company called AnaptysBio

TESARO Partnership
Under our immuno-oncology collaboration with TESARO, we have granted exclusive rights to TESARO to develop and commercialize the following AnaptysBio-generated antibody product candidates:
Anti-PD-1 Monospecific Antagonist Antibody (Dostarlimab, TSR-042): BLA Filing Anticipated in H2 2019;
Anti-TIM-3 Monospecific Antagonist Antibody (TSR-022): Dose escalation completed in Phase 1, combination trial with TSR-042 has been initiated;
Anti-LAG-3 Monospecific Antagonist Antibody (TSR-033): Phase 1 trial initiated, and
Anti-PD-1/LAG-3 Bispecific Antagonist Antibody (TSR-075): lead candidate identified, IND-enabling studies on-going.

[abdullla] 19/3/2019 19:40

GlaxoSmithKline PLC on Tuesday said data from the early-stage Garnet clinical study had promising results for the use of Dostarlimab in patients...

[dr biotech] 19/3/2019 13:05

Was a member of the ERG on R5 just now. Said he would have voted for the WA at the third time - presenter asked why as the deal hasn't changed - replied that opinion on the ground has changed. Can't say that I have seen or heard anyone that said this deal is suddenly worthwhile. More flipfloppery than Corbyn.

[steeplejack] 19/3/2019 09:45

Bercow has perfectly legitimately stopped Teresa May attempting to bludgeon parliament into accepting a deal it clearly doesn’t like.

Brexit will happen whatever a publicity seeking press might say.An extension could strengthen the Brexiteers hand.They’ll have a contingent of Eurosceptics in the EU parliament joined by an increased bunch of eurosceptics from other countries post the EU elections.

Parliament will take control of the exit process.There should be a much enhanced cross party debate (as there should have been in the first place)before Teresa May decided she had some divine right to interpret the whole Brexit purpose.

Brexit will happen,so I’d recommend the Brexit discontents put down their pitchforks and get back to their allotments.

[oriana2] 18/3/2019 18:57

Not much wisdom around at the moment....... laughingstock of the world.

[dr p1gs blood] 18/3/2019 17:34

the young ones who voted remain in 1975, grew up got wiser and voted leave in 2016

[oriana2] 18/3/2019 09:28

You mean the young people who will carry the full weight of this Brexit folly throughout their lives without having ever been able to vote on it?

[zicopele] 15/3/2019 19:31

Meanwhile GSK is going nowhere.

[dr biotech] 15/3/2019 18:48

Do we really want a free trade deal with China?

The problem is that we already have a free trade deal with the EU and through them 60 or so other countries. These will all go to WTO except a couple of fairly small ones.

The EU has bigger bargaining power than us and has deals that legally can't be bettered. So at best we are going to where we are now at some point in the future after first going on worse terms.

The are three main countries that we could make significant deals with. China - the worlds largest low cost manufacturer who would probably dump a lot of stuff on us. Trumps America first - chlorinated chicken (which incidentally isn't just about the final wash, its a more about the entire process including animal welfare). One of the things that the US would also want would be a clause that we don't make deals with some other nations. Then there is India - sticking point there is that they want visas to work over here. Thats not going to go down well with the largely anti-immigration brexiteers.

And what are we going to sell India/China? Its going to make our trade deficit worse.

[steeplejack] 15/3/2019 16:53

A facetious remark about chlorinated chicken.I really couldn’t give a stuff about chlorinated chicken.You’re right,I just won’t buy it.The point is that you shouldn’t expect that deals with the likes of the USA or China to be easy.They’ll both drive hard bargains and China will almost certainly have a political agenda.Complain about human rights etc and economic trade deals could be compromised.As far as the USA is concerned,they’ll expect you to accept hormone treated meat....(and yes chlorinated chicken)which will in turn compromise our arrangements with the EU because standards would have been compromised in their eyes.Numerous articles have been written about the lack of wiggle room provided by the necessary acceptance of trading standards.Time will tell.

[wbecki] 15/3/2019 16:36

"lippy4
15 Mar '19 - 16:32 - 19436 of 19436
0 1 0
steeplejack my last word about the eu,you drink chlorinated water don't you so whats the difference."


Steeple doesnt drink tap water, it is beneath him.

He ships his water in from the Highlands no doubt.

[lippy4] 15/3/2019 16:32

steeplejack my last word about the eu,you drink chlorinated water don't you so whats the difference.

spud gsk is not doing much today any way,by the way I have held gsk for 7 years for income.

[wbecki] 15/3/2019 16:27

"However,i would say that leaving the largest trade group on the planet is unlikely to afford economic benefits and anyone who thinks it will,better develop a taste for chlorinated chicken"

Versus the chlorine washed salad we get from EU

The Hepatitis E we get in meat from Holland and Germany

Or the chlorine washed tap water many drink every day in UK!!!

You're peddling fearmongering tripe. And you must know it.

In addition who is forced to purchase chlorine washed chicken, or chlorine washed salad, or Hepatitis E EU meat (unless it isnt labelled as such!!)

"I guess the USA and China and the like will be more than benign with their trade deals.....so we hope."

Eu doesnt have a FTA with

USA
China
et al.

UK is 5th or 6th larget global economy.

Why do you think Britain isnt good enough or big enough exactly???

[spud] 15/3/2019 16:16

Can someone change the header to BREXIT & all possible permutations please....Strewth people, there's a thread for BREXIT - Please please use it!spud

[steeplejack] 15/3/2019 16:09

It’s contentious to say we prospered under the EU.Afterall,soon after we joined we had oodles of North Sea oil revenues that makes comparisons somewhat difficult .So,I’m not saying ,unequivocally,that EU membership has benefitted this country.However,i would say that leaving the largest trade group on the planet is unlikely to afford economic benefits and anyone who thinks it will,better develop a taste for chlorinated chicken.I guess the USA and China and the like will be more than benign with their trade deals.....so we hope.

[lippy4] 15/3/2019 15:49

steeplejack

how can you say that economically we have prospered in the eu,we have an enormous deficit with them plus the costs of belonging go far beyond.

we are as a country going to be swallowed up and disected in time to suit the grand plan which the eu mysters have in mind.

the Lisbon treaty says we hand over total power to the eu and in time of course the pound will be dropped for the euro which we as a country told them it would be a disaster which has been proven.but not for Germany as it sold all its goods at a advantageous currency rate and now you have a huge mess of mammoth proportions.

I personally do not want the eu to have this power that is why I believed in leaving.

[wbecki] 15/3/2019 15:47

Who said this about LEAVERS?



"There again, the majority are old and will be dead soon.Who knows,the young might reapply for EU membership sometime in the future."

Stepplejack <-----------------------


And you have the call to call me a nasty person.

At least I dont wish the elderly were dead!!!!!