Evgen Pharma Share Discussion Threads

[moneymunch] 26/2/2021 21:51

Yep, SFX-01's evaluation by University of Rochester, New York for CKD as well as evaluation for NASH also at University of Dundee both looked very promising, and both collaborations announced just before the first lockdown, and so news more than possible, and the only mention/ reference recently is from the Half Year Report released December 2020. Gl :-)


-- SFX-01 to continue to be provided to academic groups for preclinical evaluation in selected disease models

[moneymunch] 26/2/2021 19:47

Makes you wonder if the pandemic slowed up the evaluation of SFX-01 by several institutions for CDK, NASH and also the following. Gla :-)


5/9/19

Evgen Pharma PLC Agreement for supply of SFX-01 for autism trial

[moneymunch] 26/2/2021 18:49

How Components in Broccoli are Advancing Autism Research

By Chris D'Adamo, PhD

February 10, 2021

[moneymunch] 26/2/2021 18:41

Numbers are dropping thankfully, but still no shortage of potential recruits for SFX-01's Covid/ARDS trial, and will be interesting to keep tabs on the Scottish numbers from now on in. Gla :-)


Scottish numbers: 26 February 2021

Summary

581 new cases of COVID-19 reported

20,410 new ;tests for COVID-19 that reported results – 3.3% of these were positive

27 new reported death(s) of people who have tested positive

80 people were in intensive care yesterday with recently confirmed COVID-19

924 people were in hospital yesterday with recently confirmed COVID-19

1,542,929 people have received the first dose of the Covid vaccination and 65,340 ;have received their second dose

[moneymunch] 26/2/2021 18:22

Not too sure, the threshold was crossed on the 12th, and so probably Spreadex customers selling after the 8p placing news???

[markth126] 26/2/2021 17:46

Is the spreadex related to ig clearing decks .

[moneymunch] 26/2/2021 17:41

Yep, my additional top up has gone through too, or at least my account has been debited , and I see Spreadex is now under 3% , which is a good thing imho....looking forward to market response on admission and a flow of positive news from Huw in the coming weeks to drive the share price to new highs. Gl :-)

[lovewinshatelosses] 26/2/2021 16:32

Got an additional 10K on top of my allocation. Been getting absolutely soaked today on some of my other holdings, so it would be nice if this one could stop the rot for me :) GLA.

[moneymunch] 26/2/2021 12:21

This Phase II/III trial is a randomised, placebo-controlled trial, sponsored by the University of Dundee and funded by the UK charity LifeArc. It is investigating whether the Company's lead asset, SFX-01, can reduce the severity, or prevent the onset of, acute respiratory distress syndrome ("ARDS") in patients with suspected COVID-19. Patients may be included in the study if they are infected with SARS-CoV-2 or another respiratory infections causing community-acquired pneumonia.

The trial design includes an assessment of safety and futility by a Data Safety and Monitoring Board ("DSMB") who will review unblinded data on the first 100 patients treated. In addition to the DSMB safety and futility assessment, Dundee University ("the Sponsor") has decided to review the top-level unblinded data in a preliminary assessment of possible efficacy. This may lead to adjustments to the design of the trial for remaining patients, including in patient numbers, and possibly early termination for either safety, futility or alternatively, strong efficacy. It is expected that this initial data will be available during the second quarter of calendar 2021.

[moneymunch] 26/2/2021 12:09

Covid-19: How the pandemic forged One Dundee

Published on 17 February 2021

The University has always promoted a message of “One Dundee” - of a community united in good times and bad. That ethos has been exemplified by the response of the University and our community to the Covid-19 pandemic over the past year.

....................

Having forged a reputation as one of the country’s leading lung experts, Professor Chalmers has become a regular fixture on television and radio, updating the public on his work.

“Right from the beginning of the pandemic, our scientists were here, collecting samples from people with Covid-19, helping to treat them, and trying to find new treatments by conducting vital clinical trials.

“One of the major challenges traditionally faced by scientists is the time taken to write grants for research funding. We didn’t have that time during the pandemic, but we worked with great partners, like the British Lung Foundation, that allowed us to redeploy staff that allowed us to work on Covid-19 projects.

“While an exciting time for scientists, we have always been aware of the threat posed by this illness and the sacrifices being made by so many people as we adjusted to living with it. What we can say, however, is that the research undertaken here has really helped to improve outcomes for people suffering from this disease.

“We started two major randomised trials of therapies, including the first major clinical trial led from Scotland. We also started a unique collaboration between scientists and frontline clinicians working with Covid-19 patients. Working together has helped us to produce results in a rapid timeframe.”

......................

And these are just a handful of examples of the activity that has taken place. To give an insight into the depth and breadth of our response to the pandemic, University staff or students have been involved in more than 50 initiatives related to researching the illness, or in helping those working with or affected by Covid-19.

Professor Sir Mike Ferguson, Regius Professor of Life Sciences, said, “The University has risen vigorously to the Covid-19 challenge.

“At the clinical end, colleagues in the School of Medicine and NHS Tayside have, as well as brilliantly looking after patients, been engaged in key national and international research projects and clinical trials. At the drug discovery end our Medical Research Council Unit, directed by Professor Dario Alessi, has been making all the different component parts of the virus to provide to the national research community and our Drug Discovery Unit, led by Professor Paul Wyatt, was chosen to develop new medicines for treating coronavirus infections.

“At the diagnostics end, Professor David Gray has been central to setting up and running the Glasgow Lighthouse Lab that performs 50,000 tests a day. I have also been providing a bit of advice to the UK Government on Covid-19 antibody testing and national core studies.”

And all of this hard work is beginning to reap rewards. With vaccines successfully developed and now being rolled out around the world, there is hope that we may soon return to the lives we once lived. And as it has done throughout the pandemic, the University is again stepping up and playing its role in the vaccination process.

In November 2020, we began recruitment for a Covid-19 vaccine trial, in partnership with NHS Tayside, for a candidate developed by Janssen Pharmaceuticals. With numerous vaccines required to protect the global population, our involvement is playing a pivotal role in developing a vaccine that could one day play a crucial role in reducing Covid-19 rates and saving lives.

[moneymunch] 26/2/2021 10:46

This will fly in the coming week or so I reckon, fully funded for the foreseeable, multiple shots on multiple Transformational targets, and I also reckon Huw will have one or two updates to release very soon after the 4th March, admission date, to get the share price heading North. Gla holders :-)

[moneymunch] 26/2/2021 08:39

9p trades are buys...Gla :-)

[moneymunch] 26/2/2021 07:11

8p entitlement deadline gone.....Fill ya Boots!!! Gla ;-)

[dlg3] 25/2/2021 14:27

any of you guys into Crypto? take a look at Shardcoin many projects in the pipeline and at the moment off the radar.. One of their projects at the moment take a look..

[dlg3] 25/2/2021 14:23

£12.5 million market cap with approx £13million in the bank !!! Sp should march forward even with the dilution, fully funded!!! the only way is up...

[moneymunch] 25/2/2021 12:13

James D Chalmers
@ProfJDChalmers
·
2h

As of today, >400 hospitalized patients with severe COVID19 have participated in clinical trials of new treatments at Ninewells Hospital.

Thank you to our patients and their families for their key contribution to improving care.

@TASC_TCTU
@UoDMedicine
@TASC_Research
@NHSTayside

[moneymunch] 25/2/2021 08:41

Last day for 8p entitlement, a big week ahead and plenty of potential positive newsflow thereafter to drive the share price to new highs, with Evgen fully funded for the next couple of years...Exciting times. Gla holders:-)

[moneymunch] 25/2/2021 08:24

Evgen's not on the list. Gla :-)


List of companies that the IG group now require 100% on margins. By Friday...

[amaretto1] 24/2/2021 17:08

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[dlg3] 24/2/2021 15:55

ADK is a member of the Scientific Advisory Board of Evgen Pharma, and a consultant for Aclipse Therapeutics and Vividion Therapeutics.

Albena T. Dinkova-Kostova
Affiliations
Division of Cellular Medicine, Jacqui Wood Cancer Centre, Ninewells Hospital and Medical School, University of Dundee, Dundee DD1 9SY, UK, Scotland