Share Name Share Symbol Market Type Share ISIN Share Description
Astrazeneca Plc LSE:AZN London Ordinary Share GB0009895292 ORD SHS $0.25
  Price Change % Change Share Price Bid Price Offer Price High Price Low Price Open Price Shares Traded Last Trade
  -10.00 -0.13% 7,870.00 7,870.00 7,874.00 7,888.00 7,805.00 7,805.00 57,269 08:13:48
Industry Sector Turnover (m) Profit (m) EPS - Basic PE Ratio Market Cap (m)
Pharmaceuticals & Biotechnology 18,386.4 1,167.2 77.7 99.2 103,247

AstraZeneca, Merck Get CHMP Positive Opinions for Expanded Lynparza Use

21/09/2020 3:42pm

Dow Jones News

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By Colin Kellaher


AstraZeneca PLC and Merck & Co. Monday said the European Medicines Agency's Committee for Medicinal Products for Human Use recommended approval of two additional indications for the cancer drug Lynparza.

The drugmakers said one recommendation covers Lynparza as monotherapy for the treatment of adults with metastatic castration-resistant prostate cancer and BRCA1/2 mutations who have progressed following a prior therapy that included a new hormonal agent.

The second recommendation covers Lynparza as a first-line maintenance treatment in combination with bevacizumab for HRD-positive advanced ovarian cancer.

The indications now await approval from the European Commission, which generally follows the CHMP's recommendations.

AstraZeneca and Merck in 2017 formed a collaboration to co-develop and co-commercialize Lynparza for multiple cancer types.


Write to Colin Kellaher at


(END) Dow Jones Newswires

September 21, 2020 10:27 ET (14:27 GMT)

Copyright (c) 2020 Dow Jones & Company, Inc.

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