Angle Share Discussion Threads

[boris cobaka] 11/5/2024 10:07

Morning Anglers!
From the Jan super spike rns -

4) Actionable variants identified in our patient cohort in the CTCs that were not present in the ctDNA included variants targeted by widely used drugs from many large pharma companies, for example:

· PIK3CA (E545K): Alpelisib (Piqray®) marketed by Novartis

· EGFR (T790M): Tagrisso (Osimertinib®) marketed by Astra Zeneca

· ESR1 (K303R): Elacestrant (Oserdu®) marketed by Menarini

· MTOR (T1977K): Everolimus (Afinitor®) marketed by Novartis

· ERBB2 (R678Q): Trastuzumab, Pertuzumab, Neratinib, Afatinib marketed respectively by Astra Zeneca, Roche Genentech, Puma Biotechnology, and Boehringer Ingelheim



Maybe a few took notice.

[adw198] 11/5/2024 08:54

Morning Nigel
Fair summary and yes I acknowledged they’ll be things we’ve not heard about, we just don’t have alot to go on to tell us whether they’re on track.

@krpyton they lost £21m in 2023 and the savings were forecast to reduce costs by £3m. So that would be circa £18m loss this year, with a starting cash pile of £15m. So you tell me how cash will last till Q2 without considering revenue?

[nigelpm] 11/5/2024 08:46

We’ve had a $250k deal, a £150k deal and the £500k deal with AZ that complete Q1 25.

That's what they've disclosed in RNS. There will be other things and also worth notng from Nov 23 RNS there weresales secured in 2023 that will be recognised in 2024:


The Company expects revenue recognised for 2023 will be c. £2.2 million, which is an increase of 120% over revenue achieved in 2022 but below current market consensus of c. £3.0 million. New sales secured in 2023 are expected to be c. £3.3 million however revenue recognition for some of these sales will fall into the 2024 financial year.

It's clearly taking longer than expected to build revenue and there will likely need to be another fundraise but it's about momentum and the quality of customers they are building.

[adw198] 11/5/2024 08:43

@krypton
Are you really claiming the cash runway projection doesn’t consider revenue? That would be a weird way of budgeting!

[kryptonsnake] 11/5/2024 08:36

"Gross margin for H2 is expected to be higher than H1 reflecting the product-service mix and, together with tight cost control, to result in the cash position at 2023 year end being in line with consensus at c. £15 million."

"The cost savings from the streamlining of our clinical services business will now extend the forecast cash runway into Q2 2025"


£15m in cash is expected to last until Q2 2025. This has nothing to do with revenues. The cash they had end of 2023 will last until Q2 2025

Can't make it any clearer for those too thick to understand


sent from my iPhone

[adw198] 11/5/2024 08:22

@hoohah In November they guided the market they expected to triple revenue to £6m. Based on that massive growth projection they forecast cash lasting till Q2 25.
Some of us are concerned whether we’re on track to achieve £6m because there’s no evidence to suggest that. We’ve had a $250k deal, a £150k deal and the £500k deal with AZ that complete Q1 25. Fair enough we don’t what else is being achieved that they haven’t announced and that’s particularly true of product sales but at the very least it’s a risk. If they aren’t on track and need to guide the market the results will be the time to do it. Those results are strangely later than previous which might suggest a placing will be announced around the same time. A placing isn’t the end of the world and I personally will almost certainly buy back in after it arrives because for me it de risks the prospects here. But it would most likely lead to a drop in the share price


Bones knows this very well because it’s the kind of analysis he applies to some of the many other message boards he slates other shares on. He just happens to want to pump the price here which is why he’s so aggressive to anyone who doesn’t play along with his agenda. What he’s admitted is he sold in January the exact time he was posting regularly about how great things were. Yet he’s also announced he hasn’t sold a penny.

Even if the above results / placing does play out it’s also possible there could be a stonking deal announced any time to send the share price much higher. That’s fine with me, we also have to make our own decisions and live with the consequences. I watched RENE go to nothing from a similar position so just want to manage my risk. Results will be in the next 2 weeks so the good news is we’ll be finding out very soon.

[fhmktg] 11/5/2024 08:08

ESMO breastcancerconference Berlin May 15-17th
Update to coincide?

[hoorah henry] 11/5/2024 07:32

Washingmachine, they have already informed the market what results look like back in November, so should be no surprises and future outlook and projections commentary will be main point of interesthTTps://uk.advfn.com/stock-market/london/angle-AGL/share-news/Angle-PLC-Trading-and-business-update/92507420

[washingmachine] 11/5/2024 07:22

Add POLX to that list
You can all read, make your own mind up on this character.
Don’t be fooled on here

[washingmachine] 11/5/2024 07:16

Bones you are on at least five other threads / components talking about placings
GDR being your latest today,
Talk about pot kettle black.
AGL will announce a placing, coinciding with the next results
The results will miss projected forecast of 6 million
Pretty odvious, what’s more obvious is that the Shareprice will retreat
No matter your constant barrage of posters having a truthful opinion
That clearly doesn’t fit your agenda of the time
Especially your new found devotion of everything Andrew Newland
You are a very manipulative poster, very similar traits to Pwhite
Who’s coming very unstuck on VRS !

[havinthelasttoast] 10/5/2024 22:09

Timberrrrrr

Any bag holders raise your hands !

[waterloo01] 10/5/2024 18:51

So much noise, but welcome to see some progress with further collaborations ahead. Short of a takeover (not impossible) happy to see them get embedding as a companion diagnostic. A bit daft having to test against each and every one but so says the FDA..

Back into hiding. Much too noisy with traders for my liking.

[bones699] 10/5/2024 18:19

Heading back to 12p lol!

[bones699] 10/5/2024 18:19

10p for the company that's overpriced I want a discount!

[havinthelasttoast] 10/5/2024 17:24

Pump and dump over then now?

Placing anyone. 10p ?

[boris cobaka] 10/5/2024 16:38

Those were the sells that spiked thus lower at 2.30 around 780k

[boris cobaka] 10/5/2024 16:25

Looks like my leftover toast wasn't AN likeness after all dammit. Elmo again.

[muffster] 10/5/2024 16:23

699 says buy (secretly)

[bones698] 10/5/2024 16:21

Yes same time as the 4x100k.blocks buys went through too. Tr1 coming perhaps they have held this down today filling an order

[adw198] 10/5/2024 15:58

I’m relieved it didn’t 16p as I’d have been in turmoil about whether to buy! On one hand it would have been good to buy back at the same level I sold with the addition of the 2nd AZ deal. On the other, well you know my thoughts on what might be brewing…

[boris cobaka] 10/5/2024 15:52

I was a mite disappointed we didn't get that 16p spike down, still might of course but I have to say I've been impressed with the volume over the last week.

[boris cobaka] 10/5/2024 15:46

Adw - modest trading pot.