Trellus Health Share Discussion Threads

[wan] 16/10/2024 07:34

The change I highlighted in post 349 regarding clinical trial research organizations is notable, although the market remains distinctly unimpressed.

I had a quick look today on what is happing within the UC and IBD market.
Ulcerative colitis (UC) is an inflammatory bowel disease (IBD).

Abivax reports positive interim results for obefazimod
Pharmaceutical
3 October 2024

French drug developer Abivax (Euronext Paris: ABVX) today announced the results of an interim efficacy and safety analysis of an open-label maintenance (OLM) study that enrolled patients with ulcerative colitis (UC) at the conclusion of the Phase IIa and Phase IIb OLM studies, where they had received obefazimod 50mg once daily.

“These important data further support the potential of obefazimod as a promising therapeutic option for patients with UC,” said Dr Marla Dubinsky, co-director of the Susan and Leonard Feinstein IBD Clinical Center at Icahn School of Medicine at Mount Sinai New York. “The results observed at a lower dose are particularly encouraging, as clinicians often like to have the option to de-escalate dosing once patients achieve remission,” she noted.


Abivax enrols first participant in Phase IIb Crohn’s disease drug trial
The trial is designed to assess the efficacy and safety of the once-daily dose of the drug compared to a placebo.

The double-blind, multi-centre, randomised, placebo-controlled trial is structured into three treatment portions: a 12-week induction phase, a 40-week maintenance phase, and a 48-week extension phase.

It is designed to assess the efficacy and safety of the once-daily dose of the drug as both an induction and maintenance therapy when compared to a placebo.
Full story -

[tomboyb] 16/10/2024 06:27

1.2mill dumped at 0.72p yesterday well below bid -

[tomboyb] 15/10/2024 13:13

This is on their broker that brought this to market -

SINGER hang your head in shame!

[tomboyb] 15/10/2024 13:12

Shocking their app has only 100 downloads -

Never seen anything as bad as this -

100 downloads!!!!

[tomboyb] 15/10/2024 12:57

They've spent over $22million for a party imo -

They will party with the rest of the cash -

[casholaa] 15/10/2024 12:26

The video just sound like babble to me.

[tomboyb] 15/10/2024 12:04

This should be suspended -

[tomboyb] 14/10/2024 13:23

This should be suspended -

[tomboyb] 09/10/2024 14:29

New Video from Trellus -



The more I see and hear , the more worse it gets -

The app is given away free! -

No one wants it even when free -

100 downloads, if you had family and friends you could do that in a day for less than £50 -

Its taken then 3 year,, $22million and a resilience team (a bit like massage teams you get in a shopping mall) that no one wants i.e $50 turnover -

[tomboyb] 09/10/2024 13:35

dont know -

Singer floated this dud -

I would avoid any singer IPO after this -

[casholaa] 09/10/2024 13:06

I now have no idea how they managed to float this.

[tomboyb] 09/10/2024 12:56

LOL!

Surely they will have to suspend this -

Just looks like a shell company that has raised a hell of a lot of money and spent it -

[casholaa] 09/10/2024 12:07

It could have been a lot worse, it could have been 99 downloads!

[tomboyb] 09/10/2024 10:10

100 downloads and zero reviews -

That is what you get after spending well over $22million -

Where is Singer? -

[tomboyb] 09/10/2024 09:51

I'm actually shocked -

100 downloads -

The worst of the worst apps get more than that -

[tomboyb] 09/10/2024 09:36

Singer bought this company to market -



Free App that absolutely no one wants -

They will wind this down when cash has dwindled to zero -

[tomboyb] 09/10/2024 09:30

Thats been since 2021! -

They have spent over $22million for 100 downloads - '

lol!!

[wan] 09/10/2024 09:22

For me it's about; what's changed?

Trellus had previously highlighted that they had signed licensing agreements with two large pharmaceutical companies. But now there is an increased commercial focus on agreements with pharmaceutical companies 'and' clinical trial research organizations (CRO's).

They have not mentioned CRO's previously, and the fact they are increasing their commercial focus on these two areas almost certainly implies their is interest coming in the other direction.

The fact they are in discussions with potential partners across 'all' of their commercial models, including two later-stage discussions, is encouraging, but as I said previously, I am not holding my breath.

[tomboyb] 09/10/2024 08:49

100+ downloads -

What a con! -

[tomboyb] 09/10/2024 08:19

There is no one on the platform save a few -

No one is interested so I wonder how on earth they managed to raise $28million -

Only $6-$7mill left and that will decline to zero -

Singer should be ashamed -

[wan] 05/10/2024 04:54

Transitioning to a platform technology that is condition-agnostic and which can be applied to many areas beyond chronic condition management might provide the financial catalysts required for change.

The increased commercial focus on agreements with pharmaceutical companies and clinical trial research organizations (CRO's) might well provide a catalyst for a re-rating (if successful!). Success in this area could make Trellus a particularly attractive bolt-on acquisition target for CRO's.

Given the financial performance to date though, I am not holding my breath, but there might just be a glimmer of light at the end of the tunnel!

[casholaa] 04/10/2024 16:42

I'm hoping the platform can be applied for multiple disciplines

[tomboyb] 30/9/2024 12:05

This company should be investigated -

One of the worst I've seen for s while -

[tomboyb] 30/9/2024 11:32

Revenue 2020 0
Loss - $762,000

Revenue 2021 - $25k
Loss - $7.6 million

Revenue 2022 - $18k
Loss - $10.2 million

Revenue 2023 - $19k
Loss $6.9million

Massive Losses -

From LSE they probably have around $6mill left -

This does not look right to me at all -

[tomboyb] 30/9/2024 09:38

James Robert Kight selling out of this -

looks like a con -