Skinbiotherapeutics Share Discussion Threads

[bobalot] 14/12/2017 14:18

Lounge -- an excellent Vogue magazine article:


Why Probiotic Skin Care Is (Actually) Worth It, According to Experts

December 13, 2017 2:14 AM by Lauren Valenti

Thanks to the probiotic trend that’s emerged over the past few years—miracle tonic kombucha serving as its fizzy fuel—fraternizing with the bacteria that lives in our microbiome (yes, all 100 trillion of them) has become relatively normal.

So much so, in fact, that it’s inspiring health-minded individuals to infuse not only their diets but also their skin care with more “good” bacteria.

“For skin, probiotics work in a similar way as they do for the digestive system,” explains New York dermatologist Dr. Francesca Fusco.

“They help it [to] remain in a balanced state.” Surface-level, this translates to a complexion that’s not too dry nor too oily, and skin that can effectively repel the environmental conditions that cause inflammation. In other words, if you want a flawless glow, nurturing your skin flora is the place to start.

From maintaining a healthy bacterial balance in the skin to treating flare-ups and breakouts of all sizes, here experts weigh in on why a probiotic-laced skin-care regimen actually works.

The Balancing Act

According to Dr. Whitney Bowe, probiotics benefit the skin in three key ways. First, they act as a protective shield by preventing bad microorganisms from provoking an immune reaction. “This creates a more calming environment for the skin,” she says.

Second, they produce natural antibiotics called antimicrobial peptides that combat bad bacteria. And lastly, they boost the skin’s functionality in dealing with external damaging factors including free radicals, sun, and pollution. “All of these benefits help to reduce inflammation,” she says. “This helps reduce flare-ups and preventing premature aging.”

Prebiotics, which are a food source for the bacteria, are also beneficial to recalibrating the skin microbiome. “Probiotics are the good guys and prebiotics contain what the good guys consume to make sure they thrive and proliferate,” says Bowe. “Prebiotics also promote a more diverse array of bacteria, and diversity is key to healthy skin.”


The Fortifying Factor

Probiotic moisturizers and treatments can aid all skin types, but are especially beneficial to those with chronic inflammation. “For those with acne, or skin conditions like rosacea and eczema, [probiotics] can yield calmer skin and better control over breakouts,” explains Fusco.

A recent study also found that because living microorganisms on the skin are recognized as foreign by the body’s immune system, it naturally springs into action against the potential threat, resulting in less inflammation, redness, and bumps.

The Gentle Approach

Too often, face washes veer harsh and strip the skin of its natural oils, leaving it looking and feeling drier than ever before. This is especially problematic in the winter, when your skin craves moisture the most.

A probiotic or prebiotic cleanser, like La Roche-Posay’s prebiotic thermal water–infused Hydrating Gentle Cleanser, will help fortify the skin’s beneficial microflora, and thus, keep the skin’s natural invisible barrier healthy, says Bowe.

[loungeact] 13/12/2017 18:42

Why Probiotic Skin Care Is (Actually) Worth It, According to Experts -

[onedayrodders] 13/12/2017 14:45

crikey 200k sell in the 7's ... obviously moving to cryptos !

[bobalot] 12/12/2017 14:37

And so is this, however SBTX have now overcome many of the hurdles cited in the article through their successful toxicity tests for H&S.

Translating Skin Microbiome Research into Clinical Products

[bobalot] 12/12/2017 14:32

Nice find lounge, here is an interesting article:

Probiotics on the Skin: An Undiscovered World


The skin microbiome field is booming and one can expect plenty of exciting scientific results coming out over the next few years. Furthermore, with the first products already launched, there will be more scientifically proven products on the way to market. These novel products will change the way we see skin care.

[loungeact] 12/12/2017 12:32

Microbiome R&D and Business Collaboration Forum: Europe - Cath O'Neill is listed as a speaker. -

[slartybartfaster] 12/12/2017 08:59

Hey bob or ibug whatever you want to go by today. Learn from the master. Note no hype and well delivered observations with a nailed prediction thrown in which is confirmed this morning. Underlined for you.

elrico - 28 Oct 2017 - 09:35:26 - 28532 of 30017 OptiBiotix - Better Science, Better Health. Better buy some! - OPTI
Imnotlong - I hope this don't come across as being condescending fella...I think you misunderstand certain commercial aspects and strategy in place. For example Nutrilinea do not have a sales role as such, they manufacture products, just as SACCO manufacture the LP-LDL raw ingredient for said products. Of course both SACCO and Nutrilinea can reel in new clients, just as SACCO seem to be within the dairy market...but lets try to keep a complex situation a little simplified.

Raw ingredients - SACCO, Production of products - Nuttrilinea
Product sales - HLH, PharmaBiota, Galenicum. These will be a mix of B2B and B2C and or both.

Between SACCO, Nutrilinea, HLH, PharmaBiota and Galenicum OPTI have a minimum of 3 revenues streams PER PRODUCTS. For example, PharmaBiota have 3 products containing LP-LDL - So SACCO x1, Nutrilinea x3 and PharmaBiota x3 = 7 revenue streams.

HLH, PharmaBiota and Galenicum have all launched products containing LP-LDL, so revenues will be coming in from these. Timing of receipts has yet to be determined, as per intimated yesterday.

TATA/LPGOS goes into pilot production in November and full production in December once optimisation has been established. LPGOS will go into a variety of products, ranging of nutraceutical food and OTC products...so the scope for multiple products is huge as is the market.

I suspect TATA/SlimBiome will be in 2018 - Christina is readying for a big SlimBiome push for 2018. I know it appears to have been very quiet here but she has been very busy putting certain aspects in place ready for 2018.

CII/SlimBiome possible collaboration for cereal ingredients and supply ingredients for cereals and hot & cold snacks.
-----------------------------------------------------------------------------
Retail store push in 2018

OPTI in-house Wellbeing consumer online sales for products containing OPTI's, Cardiobiome, CholBiome, SlimBiome, OptiBiome, ImmunoBiome.

[loungeact] 12/12/2017 07:40

ODR - LOLOL!! Good find. He has no integrity.

[onedayrodders] 11/12/2017 20:37

bobalot - 09 Nov 2017 - 12:56:22 - 802 of 1194 SkinBioTherapeutics PLC - Multi $bn skin health opportunities. - SBTX
OPTI is making loads of progress and so is SkinBio -- microbiome platforms are going to change the way we view treatments

bobalot - 11 Dec 2017 - 10:34:54 - 29960 of 30001 OptiBiotix - Better Science, Better Health. Better buy some! - OPTI
Flushed down the cash toilet on untruths and unrealistic deals imo.


LOLLLLLLLL !!!!! Talk about U turn you should be a politician

:O)

[f3rdinand] 11/12/2017 20:05

Bob...no-one is disagreeing with your SBTX research... a future major player in the microbiome space 'potentially' I don't understand why you have such a huge chip on your shoulder? Give the endless messages a rest as mentioned earlier; it looks bloody desperate!

[bobalot] 11/12/2017 19:35

LETS GET IT RIGHT --- COMMERCIALISATION EARLY NEXT YEAR imo...with a major player in place already along with a major mass manufacturer already in the planning stages of production before human testing begins.

That all speaks of a high level of confidence for the tech....Dr. Cath has just been given an accolade of awards by her scientific peers for the work done...

THUS THE TECH WORKS AND WILL REACH A HUGE MARKET AT THE RIGHT PRICE.

[bobalot] 11/12/2017 19:34

The business is in the company of a leading edge researcher who wins awards for her work.

CEO Cath O'Neill named one of this years 50 female Movers and Shakers in the UK healthcare industry

CEO Cath O’Neill named one of this years 50 female Movers and Shakers in the UK healthcare industry by @BioBeatUK.

The annual report aims to celebrate exceptional female leaders and bioentrepreneurs who are driving innovative thinking within the industry.

Cath has been recognised for her outstanding research into skin health as well as spearheading the success of SkinBioTherapeutics

[bobalot] 11/12/2017 19:33

THIS IS A KEYSTONE ANNOUNCEMENT ABOUT HEALTH AND SAFETY APPROVAL AND ANNOUNCES THE START OF HUMAN TESTING EARLY 2018...the testing only takes a month, so selling the stuff next year through a major brand name will happen imo.


SkinBiotix® platform passes additional external toxicity tests

SkinBiotix® platform passes additional external toxicity tests.
Scientific progress on track.

Manchester, UK – 9 November 2017 - SkinBioTherapeutics plc (AIM: SBTX, the “Company”;), a life science company focused on skin health, has passed two additional and final third party cellular toxicity tests for its SkinBiotix® technology.

The in vitro tests, for photo-toxicity (sensitivity to sunlight) and ocular toxicity (effect on eye cells), follow on from the recent first stage cytotoxicity tests, as announced on 3 October 2017.

The studies were again conducted by Charles River Laboratories, a Contract Research Organisation (CRO), in accordance with the OECD Principles of Good Laboratory Practice.

In the photo-toxicity test, the testers were looking to determine whether the SkinBiotix® technology would become toxic to cells when exposed to UV and visible light. The results showed that SkinBiotix® is non-phototoxic.

The second test, for ocular toxicity, was carried out to determine whether SkinBiotix® is toxic to eye cells. This involved measuring for two important components which are predictive of irritation, corneal opacity (cloudiness) and permeability (ability to let fluids pass through the eye). The SkinBiotix® technology also passed this test.

SkinBioTherapeutics will continue developing the technology towards the three applications in skin care, anti-infection and skin repair.

Dr Catherine O’Neill, CEO of SkinBioTherapeutics, commented:

“Since announcing that the SkinBiotix platform passed the key cytotoxicity test in October, we have been focussing on further proving its efficacy."

“With this news today, the technology has passed the three necessary toxicity tests showing that it can be safely applicable across our three target markets."

“We are continuing formulation development and are confident about starting our human studies in 2018.”

[bobalot] 11/12/2017 19:32

Here is a reminder...AGAIN FOR THOSE WITH SHORT MEMEORIES.



HERE IS THE FIRST INTERNATIONAL PATENT --- many others will follow on very soon.


Notification of first patent grant

Manchester, UK - 1 December 2017 - SkinBioTherapeutics plc (AIM: SBTX, the "Company"), a life science company focused on skin health, announces the granting of the first patent for its SkinBiotix® technology in Australia.

The patent granted covers the use of specific probiotic bacteria and lysates in the treatment of skin in health and disease. This marks the Company's first patent to progress to grant from within its portfolio of patents pending estate.

The patent, numbered 2013246701 and entitled 'Probiotic bacteria', runs until 15 March 2033.
The patent is in active prosecution in other locations worldwide including Europe, USA and China.

Dr Catherine O'Neill, CEO of SkinBioTherapeutics, commented:
"The Australian skincare market is a key global market. The progression and successful grant of the first national patent to emerge from the Company's Skinbiotix® patent family underpins the commercial potential worldwide.
"This is a step forward in preparing for human trials, which are scheduled for 2018."

[elrico] 11/12/2017 16:49

TBH I thought about it before I was looking at 30% loss on my entry. However, given my average is likely to be considerably lower once I GET MY FREE SHARES, I don't see the logic in crystallising a loss now (as tempting as it may seem) especially as I am significantly overweight in OPTI as it is. I'd rather be adding to SBTX...just not right now - Nearer April perhaps.

One thing to note...the investor meeting did nothing for the SBTX share price There is no rush here just yet. The smart money will trickle in under the radar and most likely be OPTI investors because they know exactly what SBTX have to offer.

A word to Bob. I have 30+ OPTI investors on my email contacts and 2/3rd have you filtered. You're as welcome as a fart in a space suit. Just to be sure...that is not intended as a compliment.

[loungeact] 11/12/2017 16:40

Think I may do the same. Little point in holding here as I'll be getting FREE SHARES from being an OPTI holder anyway and news from SBTX will take a while. May as well buy more into OPTI..

[incanus] 11/12/2017 16:32

Sold today to add to opti as i expect better share price news over the next few weeks. 23% loss here but if ill get that back with adding to opti.

[loungeact] 11/12/2017 15:57

Price not looking good today. Capitulated. Will take a long time for this to grow, but i'm patient.

[bobalot] 11/12/2017 15:51

Todays price is about as good as it gets as a buying opportunity into SkinBIO...strong buy....come and get it imo.