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Share Name Share Symbol Market Type Share ISIN Share Description
Scientific D. LSE:SDI London Ordinary Share GB00B3FBWW43 ORD 1P
  Price Change % Change Share Price Bid Price Offer Price High Price Low Price Open Price Shares Traded Last Trade
  +0.00p +0.00% 33.50p 33.00p 34.00p 33.50p 33.50p 33.50p 175,846 08:00:00
Industry Sector Turnover (m) Profit (m) EPS - Basic PE Ratio Market Cap (m)
Electronic & Electrical Equipment 1.4 1.7 1.8 18.5 29.76

Scientific Digital Imaging Share Discussion Threads

Showing 1476 to 1500 of 1500 messages
Chat Pages: 60  59  58  57  56  55  54  53  52  51  50  49  Older
DateSubjectAuthorDiscuss
15/1/2019
22:43
.............. Alzheimer's and ProReveal .................. I have been doing a lot of research on the prevalence of Alzheimer's and how the numbers of people getting it keep on rising and rising. ( read my last post) Plus it is widely thought that the majority of cases never get properly diagnosed or even reported as many families look after their own elderly. Something called Amyloid Beta protein has been linked with Alzheimer's in that it appears in the brains of many Alzheimer's sufferers. There is a great medical debate now going off and has been for several years now that Amyloid Beta protein is a form of prion protein. Which if the medical profession concede to or agree with ... means that Alzheimer's becomes a transmissible disease ie you can acquire it from a dirty surgical instrument. IMHO from what I have read thus far in the last 2 years on the subject I truly believe that Alzheimer's is indeed a form of prion disease and thus you can catch it. More Neurosurgeons get Alzheimer's than the norm More Alzheimer's carers get Alzheimer's themselves than the norm Interestingly the country with the highest %age of Alzheimer's sufferers is Finland ( Where CWD has been detected recently as in the USA with Deer/Moose and Elk) Guess what ... the USA comes in at number 2 on the list with 50% of USA states affected by CWD. May 2018, Evidence of amyloid-β cerebral amyloid angiopathy transmission through neurosurgery '' Amyloid-β (Aβ) is a peptide deposited in the brain parenchyma in Alzheimer’s disease and in cerebral blood vessels, causing cerebral amyloid angiopathy (CAA). Aβ pathology is transmissible experimentally in animals and through medical procedures in humans, such as contaminated growth hormone or dura mater transplantation in the context of iatrogenic prion disease. Here, we present four patients who underwent neurosurgical procedures during childhood or teenage years and presented with intracerebral haemorrhage approximately three decades later, caused by severe CAA. None of these patients carried pathogenic mutations associated with early Aβ pathology development. In addition, we identified in the literature four patients with a history of neurosurgical intervention and subsequent development of CAA. These findings raise the possibility that Aβ pathology may be transmissible, as prion disease is, through neurosurgical procedures.'' ''The possibility of transmission of Aβ proteopathic seeds should be taken into account when assessing the safety of surgical procedures, including the adequate sterilisation of reusable surgical instruments [14, 46] and use of disposable instruments where appropriate.'' hTTps://link.springer.com/article/10.1007/s00401-018-1822-2 Recent medical articles in the last 12 months have shown prions were present on the skin and eyes of people that had died from various forms of CJD ( a prion disease) IMO such prions are also present on the skin and eyes of people that die of Alzheimer's How many people suffering with earlier stage Alzheimer's have various operations that are none neurosurgical eg appendix removal or a hernia operation At present Health Technical Memorandum 01-01: Management and decontamination of surgical instruments (medical devices)used in acute care Does not specify that surgical instruments should be tested after being used on Alzheimer's sufferers hTTps://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/536144/HTM0101PartA.pdf I think it should and soon will Why has the guidance been updated? HTM 01-01 has been updated to take account of recent changes to the ACDP-TSE Subgroup’s general principles of decontamination (Annex C). In relation to the decontamination of surgical instruments, this principally relates to paragraphs C21 and C22: Protein detection C21. Work commissioned by the Department of Health indicates the upper limit of acceptable protein contamination after processing is 5µg BSA equivalent per instrument side. A lower level is necessary for neurosurgical instruments. C22. It is necessary to use protein detection methods to check for the efficient removal of protein from surgical instruments after processing. Protein levels are used as an indication of the amount of prion protein contamination. Ninhydrin swab kits are commonly used for this purpose,but recent evidence shows that ninhydrin is insensitive. Furthermore, proteins are poorly desorbed from instruments by swabbing. Other commonly used methods have also been shown to be insensitive. The above however only is being applied to Eye surgery ( near the brain ) and Neurosurgery ... what a crass mistake methinks
buywell3
14/1/2019
07:22
...............USA and contaminated surgical instruments .................. I have just looked at what things are specified re CJD ( a prion disease) and the cleaning of surgical instruments in America. The guidance is very out of date and testing and measurement of protein residue on the face of surgical instruments after cleaning/washing/sterilization does not seem to even get a mention. hTTps://www.cdc.gov/prions/cjd/infection-control.html hTTp://www.ast.org/uploadedFiles/Main_Site/Content/About_Us/Standard_Decontamination_%20Surgical_Instruments_.pdf Hence I forecast that in the USA the first animal form of TSE to cross the barrier to humans ( might be CWD ) will go through the USA like wildfire. If Alzheimer's is proved to be a prion disease ( see my AZN thread ) ... then it already is. The USA has one of the highest rates of Alzheimer's in the world Proportion of People With Alzheimer’s Disease in the United States by Age: 85+ years, 38%, 75-84 years, 44%, 65-74 years, 15%, , and it is lethal ... no cure ... just like a prion disease. hTTps://www.alzheimers.net/resources/alzheimers-statistics/
buywell3
13/1/2019
23:01
............. ProReveal : The story so far ............... I have made no secret that it was ProReveal which first attracted me to SDI. The need for such an instrument was and now is even more evident as the incidence of prion disease gets worse as the understanding of what it is and how many types of it exist. The Department of Health (DOH) realize this and acted albeit very weakly IMO when it issued this in 2013 hTTps://www.gov.uk/government/publications/management-and-decontamination-of-surgical-instruments-used-in-acute-care But typically of the wimps that we get as Ministers of Health the title was Guidance Decontamination of surgical instruments (HTM 01-01) See it was that one word that showed how spineless Jeremy Hunt was .. (and still is regarding Brexit). The word was .... GUIDANCE This guidance was update in 2016 8 July 2016 Updated the documents based on the Advisory Committee on Dangerous Pathogens' Transmissible Spongiform Encephalopathy (ACDP-TSE) subgroup guidance, the views of the Society of British Neurological Surgeons and to align with UK devolved administrations. (Previously decontamination of surgical instruments (CFPP 01-01)) So it was updated regarding '' Transmissible Spongiform Encephalopathy '' and dangerous pathogens Just so we understand what the DOH does not want to say to the public This means ..... TRANSMISSIBLE PRION DISEASES hTTps://en.wikipedia.org/wiki/Transmissible_spongiform_encephalopathy Transmissible spongiform encephalopathies (TSEs) are a group of progressive, invariably fatal, conditions that are associated with prions and affect the brain (encephalopathies) and nervous system of many animals, including humans, cattle, and sheep. buywell Note : you can add loads of other animals to that list above now , including deer which have TSE in over 50% of all USA states and just over a year ago Camels. Governments around the world are keeping a lid on just how bad the situation is with prion diseases. Because there is no cure , prions are not alive and thus can't be killed . All humans have prion protein naturally within their body. It is mutations of it that kill us PRNP prion protein [ Homo sapiens (human) ] Gene ID: 5621, updated on 6-Jan-2019 hTTps://www.ncbi.nlm.nih.gov/gene/5621 Re ProReveal and the current uptake of it within the NHS & DOH guidance HTM 01-01 I am going to put up a post on here soon where I will urge the SDI BOD to either but preferably all: put a one page ad in a daily newspaper put a youtube video of an interview with either the Chairman or CEO Contact their local MP to make him aware of the ProReveal situation within the NHS get a radio and TV interview to explain the situation This is why In the USA Hospitals are FAILING federal inspections involving dirty surgical instruments and no SSI (surgical site infection) surveillance documented for surgeries where contaminated instruments were entered on Adverse Event Reports hTTps://www.detroitnews.com/story/business/2018/11/28/dirty-instruments-cause-second-dmc-hospital-fail-federal-inspection/2123582002/ This type of problem is costing the USA $ Billions a year SURGICAL SITE INFECTIONS CONTINUE TO HAUNT THE HEALTHCARE INDUSTRY Sep 14, 2016 hTTp://research.sklarcorp.com/surgical-site-infections-continue-to-haunt-the-healthcare-industry “The estimated cost of SSI’s to hospitals is $7.4 billion, with 13,088 deaths per year”. A 'compliance check' at this UC San Diego hospital finds surgical instruments with 'red stains on ' California Dept of public Health declared ''Immediate Jeopardy'' this has happened 7 times before at the same Hospital , a fine imposed of $44,000. Proper cleaning required before sterilization hTTps://www.youtube.com/watch?v=Ufv_YnbQgCw hTTps://www.10news.com/news/team-10/dirty-surgical-equipment-at-uc-san-diego-hospital-sparked-serious-state-response Seems a fairly common USA problem Dirty, missing instruments plague DMC surgeries hTTps://www.detroitnews.com/story/news/special-reports/2016/08/25/dirty-instruments-plague-dmc-surgeries/89303582/ Then the same problem at the same Hospitals occurs again Inspections begin at DMC hospital after dirty instruments allegation hTTps://www.detroitnews.com/story/business/2018/10/10/inspections-dmc-hospital-instrument-allegation/1587916002/ The USA has a problem Clinical Leadership & Infection Control Bone, blood, bugs found on instruments at Denver hospital after surgical breach, report says June 14, 2018 hTTps://www.beckershospitalreview.com/quality/bone-blood-bugs-found-on-instruments-at-denver-hospital-after-surgical-breach-report-says.html In the USA things seem worse than the UK but are they ? we don't know is the answer The legal bills for dirty contaminated surgical instruments grows however A widespread problem Many people may think that such events are rare, but The Center for Public Integrity points out that hospitals across the country are discovering that their surgical tools are far from clean. In some cases, staff had failed to follow manufacturer cleaning instructions but in others, contamination including bone, rust, skin tissue, blood and bacteria were discovered on the instruments after they were properly cleaned and then examined with a small video camera. Part of the problem seems to come from the advancement of medical instrument technology which now creates complex tools with movable parts that are small, and that are made out of plastics, polymers and tungsten. These materials are much harder to clean than stainless steel and glass, and therefore, sterilization is not enough to remove contaminants. Another factor may be the high volume of surgical tools which are sterilized each day and the environment in which they are cleaned. Until hospitals and manufacturers figure out a solution that fixes these issues, patients in Santa Fe Springs and elsewhere will continue to find themselves exposed to harmful superbugs and other contaminants. Patients who are victims of these medical issues may find it helpful to speak with a personal injury attorney. hTTps://www.dixondaleylaw.com/Articles/Contaminated-surgical-instruments-Are-you-at-risk.shtml But at least checks get done in America ... and Hospitals are getting named ............................... What about the NHS ...................................... What UK Government Inspections are carried out on NHS Hospitals to see that procedures and testing checks are done to collate data and avoid dirty surgical instruments and SSI's (surgical site infections) and that Hospitals document and keep records up to date ? What UK Government agencies are doing the above ? I don't think anything is being done whatsoever and that the majority of NHS Hospitals are still carrying on like they did 20 years ago Thus HAI's are costing over the NHS and hence the UK taxpayer , over 1 Billion a year ... but worse still people are catching nasty transmissible diseases many of which take years before they become apparent and many that kill or reduce the quality of life of the recipient of such a disease. In short a list of NHS Hospitals that comply with HTM 01-01 needs to be produced and made public In other words a list of NHS Hospitals that have adopted ProReveal to use in their SSD's
buywell3
13/1/2019
21:38
I think it fair to say that many Institutions read and act based upon guidance given by Brokers as do other investors ... my other point is that anybody can give forward share price price guidance using a number that the share price has already reached . That such type or method of 'behind the curve' guidance is being employed in what is obviously a growth stock giving decent updates and hitting record results one after another is plain and simply ... Just not good enough
buywell3
13/1/2019
20:44
That would imply that the institutional investors are effectively idiots which they may be but I doubt it. SCSW positive small mention this weekend
solooiler
13/1/2019
20:39
There is a case for an argument that the reason for the two major investors recently selling SDI is because FinnCap stuck with a forward guidance price which has already been exceeded. IMO such guidance is not forward looking ... rather the opposite in fact. As they have been for the last 2 years if you look back ... they give forward guidance IMO looking in the rear view mirror ... do they get paid for this ? The upshot is SDI is now a sitting duck for a foreign predator that would probably buy it for 44p a share
buywell3
13/1/2019
13:14
Thanks Hastings. Who's Charlie?
petewy
13/1/2019
12:36
Thanks Charley.
discodave4
13/1/2019
10:11
Hi Pugugly, thanks for posting, appreciated. The piece I was actually referring to didn't for some reason get uploaded to the site, rather it remained in print. Anyway I have dug it out and whilst nothing new it may be of use to some of the SDI newcomers. Good to see an ever increasing bunch of well informed and savvy investors here. ----Scientific Digital Imaging now HQ based on the edge of the city at Waterbeach has once more demonstrated that it is continuing on its more recent growth path, having delivered another set of excellent Interim results. SDI now boasts a number of complementary arms within its group, spanning life sciences, healthcare, astronomy and leisure markets that have an increasingly global feel. Ably navigated by Chairman Ken Ford and CEO Mike Creedon the company announced a substantial 23% increase in revenue to £8.04m, whilst adjusted pre-tax profits also jumped by a marked 32% to £1.46m. Importantly, cash generation was particularly strong with a 103% improvement to £1.53m as Ford added that it had been a record- breaking six month period for the company. Catching up with the Chairman this morning it is clear that the board is very pleased with the progress made thus far, whilst reiterating its commitment to further bolt on acquisitions. “We have a number of opportunities in the pipeline with four or five that we are currently looking at” says Ford, where he goes on to add that they are confident of tying at least one of these up by the end of the current financial year. In terms of the overall group Ford adds “we are currently firing on all cylinders with the businesses generating cash, so at present, we are happy with where we are at”. ATIK, Sentek and the Astels arms are singled out as very positive performers, whilst Ford also points out that the Synoptics operation has been turned around from a loss making business to profit, with new and more simplified products now feeding through. The ground breaking and highly acclaimed Pro-Reveal device is also making tentative progress against a backdrop of a cash strapped NHS, Ford pointing out that the NHS is actually at present going against its own DOH advice around the cleansing of hospital instruments. Looking ahead, Ford reiterates that the business is in a good place and the strategy is to continue on its growth path where it has both cash and bank facilities in place to support its business plan. Any future placing to raise additional funds would only be considered should a much larger opportunity emerge, although that doesn't appear to be on the agenda at present, the company seemingly happy to bolt-on smaller niche/complementary purchases. Although the house broker FinnCap is currently sticking with its 44p target price and adjusted pre-tax profits of £2.6m for the current year, given that SDI is running comfortably in-line with forecasts then there is arguably potential for a future upgrade to numbers. Ignoring any forthcoming addition to the wider group which would boost numbers, next years forecasts see revenue increasing to £16.8m providing for adjusted pre-tax profits of £2.9m and EPS of 2.7p. The free cash flow yield is expected to come in at 7% where net cash on the balance sheet should increase to £3.9m. Although Brexit issues have contributed to a drag on the domestic stock market and in keeping with others SDI shares have come off from its yearly high, the company looks better placed than many in this area and has prepared for any potential disruptions.
hastings
13/1/2019
08:14
Agreed hastings. I bought some more on the dips at the end of last week and am similarly relaxed and optimistic that the last three years or so's progress will be maintained.
rivaldo
12/1/2019
18:20
hastings - Done it for you - Good seach engine in your local paper!! https://www.cambridge-news.co.uk/business/business-news/sdi-preliminaries-drive-share-price-14981346 Is this the one you refer to?
pugugly
12/1/2019
17:13
Some great posts which is good to see and I particularly concur with Rhomboid. I'd just also add that regarding the institutional sales it's worth noting that where there has been significant profit, something has been taken off the table regarding a number of stocks, particularly in wake of the market turning.Very relaxed personally and extremely pleased with how things have progressed over the last three years. I'll try and dig out my piece I penned for the Cambridge News following the interims when I spoke with Ken Ford.Nothing new in that, but may be of interest now we have some more recent investors on board.
hastings
12/1/2019
09:19
Pireric, I think you hit the nail firmly on the head - this is one of all too few quality small caps as judged by any reasonable set of metrics such as cashflow, growth and valuation. I am a new holder here, but intend to add should the price remain at about these levels or below.
spann_703
12/1/2019
06:00
Eric I would add that FX aside SDI Director view re Brexit was it would have little impact other than potentially to improve the pipeline of potential acquisitions as nervous vendors make for better deals. I’d also say it’s eminently possible for private investors to take up the slack from Octopus divestment..this is a tiny company with only a £30m market cap and Octopus held only 6.8m shares as at Jan 4 RNS so only c£2.3m worth to exit completely Finally I’ve a sense that we can’t be too far off the next acquisition news which will provide a further insight into what looks a compelling growth story here I hold a few...well quite a lot actually
rhomboid
11/1/2019
21:47
Not many medium-high quality stocks at all in the small cap space yielding anywhere close to 5% free cash flow on a normalised basis, let alone 6.5 - 7% with SDI. Which I think is an absolutely major difference versus most shares trading on a calendar year 2019 P/E of sub 18x. And SDI is only on 13.1x. And forecasts look unduly pessimistic unless we get a no deal Brexit. A lot of other stocks I have looked at look good value at first glance, but then turn out to only be mediocre value when you look at their cash flow. SDI both looks good value at first glance, and then appears great value at second glance.
pireric
11/1/2019
20:52
If Octopus has taken a get out decision a massive number still to go - far more than the PI fraternity could swallow (imo) - Key will be whenthe price has declined sufficiently for another institution to decide it is good value - BUT a lot of shares are in or aproaching good value unless another meltdown coming - if so cash will be best.
pugugly
11/1/2019
19:11
I couldn't care less. More than doubled my position today and now 23% of my portfolio :0). Very cheap as I expect will transpire over the coming year. I genuinely am struggling to find stocks that offer better value. Share if you have any !
pireric
11/1/2019
12:29
Thinking of avraging down but Octopus reducing is a concern.
superadams
10/1/2019
22:07
Yes, Disco, it was noted as a sell trade. Perhaps some of the other ones noted as 'sells' were actually buys - as one might expect there to be about the same number of each if the MMs did not need to change their bids or offers.
charleyduck
10/1/2019
19:43
Hi CharleySaw the string of sell trades today so put off buying as thought it would dip down a bit, so your buy was marked as a sell trade?.
discodave4
10/1/2019
16:41
It didn't go any lower today, so was pleased to have been able to add at 34p.
charleyduck
09/1/2019
20:16
Could add at 34 but big seller around so very high chance IMO it legs lower again. Octopus and Miton both been selling over last 3 mnths, >10% of share capital
dan_the_epic
09/1/2019
13:55
Adding again at the bid today .....34p........ lovely............
soundbuy
09/1/2019
08:29
https://www.nhs.uk/news/neurology/mad-cow-protein-carried-by-1-in-2000-people/
hastings
08/1/2019
22:46
I bought in today at 34p too. They look good value now and as a holder of JDG for over 12 years I can see the comparisons.
davidosh
Chat Pages: 60  59  58  57  56  55  54  53  52  51  50  49  Older
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