Proteome Sciences Share Discussion Threads

[peverill] 18/6/2024 13:34

lol,hows the holding going SC,must be nearly at zero now.Did you see the AGM,they haven't a clue what's going on.

[small crow] 18/6/2024 12:31

Moaning Minnie. Filtered as he ads nothing new.

[peverill] 18/6/2024 07:55

How is the Galaxy test coming along,I only ask here because Pike doesn't seem to have a clue and there is always someone way ahead of the curve on here,who seems to know more than the company does ;-)

[elpirata] 15/6/2024 13:53

aye, & covid propelled them to 2p

[monte1] 15/6/2024 09:51

Pre kitchengate iirc.

[goggin] 14/6/2024 23:46

https://x.com/business/status/1801736908185190580?t=_TPqDfR_1MJcszMpaAsrTg&s=19Bird flu? Any possibility for prm? Who knows, bse propelled them to 1.80 20 plus tears ago

[barry evans] 13/6/2024 16:56

Amended accordingly.

I wouldnt want to post misinformation on a free bb*.


*forum

[goatherd] 13/6/2024 16:43

I think you are on the wrong thread Barry! :-)

(This is Proteome, your post is putting inaccurate hypothoses about Kefi Gold and Copper.)

[barry evans] 13/6/2024 16:15

LOL!

Apologies all round

[peverill] 13/6/2024 16:12

Is that it for the year.A hashed together AGM where again they got off lightly and still just bringing enough in to cover the wages.I don't think this was the plan when CJP set this charade up.

[goggin] 07/6/2024 19:09

Keep an eye on Bird flu, don't know if PRM has anything in that line

[small crow] 06/6/2024 11:46

Mystified by today's trades, at least as reported here!

[pools2] 06/6/2024 09:08

wasjobber,

Yes, I've heard the same thing. TMTpro 32plex(+) hyperplexing should bring all the main mass spec manufacturers into the fold.

[wasjobber] 06/6/2024 08:47

Waters mass spec 32-plex TMTpro rumours!

[pools2] 05/6/2024 17:10

Single run multiomics is now a reality with TMTpro 32plex reagents

[colinhy] 05/6/2024 16:29

TMTPro 32 plex
from Thermo Fisher Scientific Vice President Research and Development presentation at ASMS 2024 this week.

[pools2] 04/6/2024 09:30

ASMS 2024 Conference - 3rd June 2024

Customers will soon experience the power of higher multiplexing with the launch of the Thermo Scientific TMTpro 32plex Label Reagents, enabling the analysis of up to 32 samples in a single LC-MS injection. This higher level of multiplexing is particularly beneficial for applications requiring higher throughput and depth of coverage such as chemoproteomics, peptidomics, and single-cell proteomics.

[peverill] 31/5/2024 09:52

I see personal medicine started its journey in the uk today and where were this shower,nowhere as usual.!!!

[pools2] 23/5/2024 09:15

1st May 2024

Rise of Automation in Mass Spectrometry–Based Proteomics

"Sample multiplexing, via techniques such as isobaric labeling with tandem mass tags (TMTs), has emerged as a pivotal technique in MS-based proteomics ............."

[dominiccummings] 22/5/2024 16:33

What has it to do with Northants James. Are the team being stroke tested? Or perhaps they are testing them for 'mad cow disease' or more likely 'mad goat disease'?

[peverill] 22/5/2024 12:36

I can say with 100% certainty,they weren't mentioned,and no I didn't watch it.

[barry evans] 22/5/2024 09:28

Mixed emotions for head coach Sadler as Northants are denied by Derbyshire
By Jeremy Casey
Published 21st May 2024, 07:14 BST

John Sadler admitted to a sense of dejection but also pride in his team's performance as Northants were denied a first Vitality County Championship Division Two victory of the season on a dramatic final day against Derbyshire on Monday.
Facing a victory target of 371 after Emilio Gay, with a stunning 153 not out from 161 balls, and Karun Nair (55) had powered the County to a morning declaration on 301 for three, the home side dug in to rally brilliantly from sliding to 149 for seven at tea.

From looking as if they were heading for certain defeat, they held out for the next 41 overs to finish on 261 for nine and seal the draw, with Zak Chappell going on the offensive to hit 72 from 101 balls, and Anuj Dal blocking his way to 31 not out from 131 balls.


Two late wickets did give Northants hope, and in the final over of the day Daj did nick a Ben Sanderson delivery, but the ball flew agonosingly between a gap in the six-strong slip cordon and the game was up.

For Northants, Rob Keogh starred with the ball, claiming five for 62 to add to his first innings century, while loan man Liam Patterson-White took three for 58 from 29 overs.

[pools2] 22/5/2024 09:26

10/05/2024
12:00
PRBB Auditorium
PRBB-CRG Sessions
Steven Gygi
Harvard Medical School
"Proteomics as a biological assay"
Host: Eduard Sabido
Abstract:Proteomics is the systematic analysis of proteins for their various properties including expression levels, modification state, structure, interaction partners, function, and many more. For protein expression profiling, the combination of mass spectrometry with sample multiplexing creates a unique biological assay where replicates, positive and negative controls, as well as all treatment conditions can be measured in a single experiment. Tandem mass tags (TMT) facilitate these analyses and will soon be available as a 32plex reagent set. In this talk, I will highlight several new advances with these reagents including their use in targeted proteomics assays. As an example, we created an assay to measure short-lived proteins and applied it to 4 human cell lines. We identified ~1000 proteins with targeted degradation resulting in half-lives of only a few hours--often in a cell-line specific manner.