Proteome Sciences Share Discussion Threads

[jeffian] 16/5/2022 14:06

Remember the days when we all trooped off to the AGM and fulsome reports were posted from the room?

[peverill] 16/5/2022 13:11

Timber!!!!,2p on its way.

[tom barnaby] 16/5/2022 12:53

Riiiiiiiight.

[goatherd] 16/5/2022 12:38

Just for the record I have not sold a Proteome share for quite a few years. So I still have well over 1 million.

[the bull] 16/5/2022 12:36

9.5% down pools, this share has no buyers, no support whatsoever and none of us are adding either. I will sit tight though as there is some life in the old dog and who knows, maybe that toll booth will come in to force one day. The Diggles haven't given up yet so they must see something still

[tom barnaby] 16/5/2022 11:27

When even life long rampers such as goatherd walk away from a POS, you know you are in trouble. BIG trouble.

[monte1] 16/5/2022 11:19

#59241 Oh for goodness sake. Twenty plus years have led us to the point where 0.5m is considered a ‘substantial order’ and still you peddle this nonsense. Don’t you think it is time to pull yer big boy pants on and call it for what it really is - and always was?

[tom barnaby] 16/5/2022 11:17

1 trade so far today - 12729 @3.947 (pence).

[pools2] 16/5/2022 11:14

I think you'll find the company will be worth a lot more than that.

[the bull] 16/5/2022 08:28

A few years of stunning growth may just make up for 20 years of less than stunning growth. Another 5 years then and who knows, a 25p exit?

[peverill] 16/5/2022 07:27

"Over the last 3 years",wtf were they doing the previous 22 years,while paying themselves exorbitant wages .

[mashman] 16/5/2022 07:12

where has he been all these years?

[mashman] 16/5/2022 07:10

I'm Not sure if I believe a word of it

[pools2] 14/5/2022 11:11

Proteomics Market to See Stunning Growth HTTPS://www.smudailymustang.com/proteomics-market-to-see-stunning-growth-thermo-fisher-scientific-agilent-merck-kgaa-etc/

[jeffian] 13/5/2022 14:59

Glad someone pays attention!

[stocktastic] 13/5/2022 13:48

Insert a jeffian 'it could always go 100% lower"

[peverill] 12/5/2022 13:21

We lose patent protection soon,we will need plenty of "substantial" deals to make up the shortfall in revenues.And where is this commercial stroke test?????.

[dominiccummings] 12/5/2022 12:23

Share price holding up well in these difficult times. That's the one advantage of being a 'bombed out wreck' of a company..... can't go lower!

[the bull] 12/5/2022 12:14

Well done PRM although the profit probably pays For Mr Denis's salary

[tom barnaby] 12/5/2022 08:29

What a sad state of affairs, trotting out 'that'.

[monte1] 12/5/2022 08:25

Whoosh* *not whoosh

[peverill] 12/5/2022 07:31

Substantial?? £5m would be substantial,0.5 more measly than substantial.

[wrighty41] 12/5/2022 07:08

Nice one PRM. Growing revenues over next 3yrs which will eventually reflect in a 10p+ share price imo W41

[pools2] 04/5/2022 18:11

NEW! Detect 1,000+ proteins from a single isolated cell via a triggered TMT based MS experiment. Compare and contract proteomic differences between 100’s of single cell. HTTPS://www.oxfordglobal.co.uk/biomarkers-series-uk/sponsors/proteome-sciences-2/

[colinhy] 04/5/2022 15:47

4/5/2022 US Environmental Molecular Sciences Laboratory, Department of Energy, Office of Science, User Facility NanoPOTS N2 Chip Enables High-Throughput and High-Efficiency Sample Preparation for Single-Cell Proteomics The Impact Analysis of the new workflow shows that this platform can quantify roughly 1,500 proteins from about 100 individual cells from three cell lines. The new workflow eliminates the tedious and time-consuming TMT pooling steps, improves sample recovery and proteomics sensitivity, and provides high reproducibility. The new chip and workflow also cut the processing time from the previous nanoPOTS-TMT workflow by half. This workflow improves the throughput and efficiency of single-cell proteomics. Summary The nanoPOTS N2 chip is a new high-throughput and high-efficiency sample preparation workflow for single-cell proteomics that uses a novel nested nanowell chip. The N2 chip features a total of 27 nanowell clusters containing nine nanowells each. This chip design reduces reaction volume from 200 to less than 30 nanoliters and increases the capacity from 44 to more than 240 individual cells on a single chip. Each nanowell cluster is surrounded by a hydrophilic ring that facilitates the pooling and retrieval steps of the TMT labeling protocol. The new single-cell proteomics workflow featuring the N2 chip first involves the sorting of individual cells into each nanowell. Next, reagents are used to lyse cells and reduce, alkylate, and digest proteins. The CellenONE image-based single-cell isolation system is used for both steps. After this, the TMT reagents are dispensed to label peptides, and reference peptides are added to each nanowell cluster. The N2 chip can then be integrated into the liquid chromatography–mass spectrometry workflow using a nanoPOTS autosampler. HTTPS://www.emsl.pnnl.gov/news/nanopots-n--chip-enables-high-throughput-and-high-efficiency-sample-preparation-for-single-cell-proteomics/8360