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Share Name | Share Symbol | Market | Type | Share ISIN | Share Description |
---|---|---|---|---|---|
Optibiotix Health Plc | LSE:OPTI | London | Ordinary Share | GB00BP0RTP38 | ORD 2P |
Price Change | % Change | Share Price | Bid Price | Offer Price | High Price | Low Price | Open Price | Shares Traded | Last Trade | |
---|---|---|---|---|---|---|---|---|---|---|
0.00 | 0.00% | 18.00 | 17.50 | 18.50 | 18.00 | 18.00 | 18.00 | 66,018 | 08:00:00 |
Industry Sector | Turnover | Profit | EPS - Basic | PE Ratio | Market Cap |
---|---|---|---|---|---|
Noncomml Resh Organizations | 457k | 2.59M | 0.0284 | 6.34 | 16.41M |
Date | Subject | Author | Discuss |
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11/8/2020 13:27 | To say food is a "diabetic food" is now against the law. This is because there isn’t any evidence that these foods offer you a special benefit over eating healthily. They can also often contain just as much fat and calories as similar products, and can still affect your blood glucose level. These foods can also sometimes have a laxative effect. 10. Get your minerals and vitamins from foods There’s no evidence that mineral and vitamin supplements help you manage your diabetes. So, unless you’ve been told to take something by your healthcare team, like folic acid for pregnancy, you don’t need to take supplements. It’s better to get your essential nutrients by eating a mixture of different foods. This is because some supplements can affect your medications or make some diabetes complications worse, like kidney disease. That’s what Opti is up against...try gummies for instance! | rayrac | |
11/8/2020 12:34 | Wooooow ain’t you a wonder! 👉🏾 | rayrac | |
11/8/2020 12:17 | atorvastatin (Lipitor) fluvastatin (Lescol) pravastatin (Lipostat) rosuvastatin (Crestor) simvastatin (Zocor) they are statins thicko raytard the gift that keeps giving lol | manc10 | |
11/8/2020 11:33 | ii. The use of LPLDL® in combination with existing treatments such a statins, to help lower dose and reduce side effects, whilst maintaining efficacy Isn’t there a statin mixed in with a Opti product somewhere, doing the job for LPLDL? | rayrac | |
11/8/2020 11:27 | The potential of LPLDL® for immune health properties after a number of customers have reported reduction in allergies, particularly hay fever Hayfever? Backed up by what and how many? There’s always a lack of numbers where Opti is concerned...Why state something that’s not proven? Smoke and mirrors. Someone seems to be on some sort of herb? | rayrac | |
11/8/2020 09:52 | hayfever kreature how did you know that lol you need to start reading rns.s properly | manc10 | |
11/8/2020 09:50 | The Company is also exploring:- i. The potential of LPLDL® for immune health properties after a number of customers have reported reduction in allergies, particularly hay fever ii. The use of LPLDL® in combination with existing treatments such a statins, to help lower dose and reduce side effects, whilst maintaining efficacy iii. The Company has sequenced LPLDL®'s genome and is exploring the genetic predisposition of the strain to impact on a range of health areas iv. The Company has been awarded (subject to contract) a grant to explore the effect of LPLDL® on stress, anxiety, and sleep disorders with Universities in the UK and Europe | manc10 | |
11/8/2020 09:48 | Looks like the Roehampton trial has delivered a slight improvement in BP numbers. "A statistically significant reduction in systolic blood pressure was also observed across the active study group in the 6-12-week period (6.6%, P = 0.003)". | manc10 | |
11/8/2020 09:46 | The ApoB reduction is massive. There is a company I saw present the other day whose main product is designed to do this. And this is just an add on for LPLDL.... How much is this strain worth....... | manc10 | |
11/8/2020 09:37 | Why else put out such a ranc RNS ? Already know about GRAS and Feb RNS, and 4000 candidates etc etc .... was there any new info in there ? Losing the will to invest here. Total manc imv | kreature | |
11/8/2020 09:12 | what a brilliant rns you know its a good one because the trolls are up early lol | manc10 | |
11/8/2020 09:11 | Scientific and commercial development update Tue, 11th Aug 2020 07:00 RNS Number : 6995V OptiBiotix Health PLC 11 August 2020 OptiBiotix Health plc ("OptiBiotix" or the "Company") Scientific and commercial development Update on LPLDL® OptiBiotix Health plc (AIM: OPTI), a life sciences business developing compounds to tackle obesity, high cholesterol, diabetes and skin care, provides the following scientific and commercial update on its cholesterol and blood pressure reducing probiotic, LPLDL®. Scientific update The Company differentiates LPLDL® from other probiotic products by its scientific studies into LPLDL® mechanisms of action, human studies demonstrating the strains safety and efficacy and its regulatory approvals (FDA GRAS and GMP pharma manufacture). Scientific and human studies The Company has published six studies on LPLDL® in peer reviewed journals or as abstracts at international scientific conferences. These cover the safety and performance of LPLDL® in human studies, the three mechanisms of action by which LPLDL® reduces blood lipids, and LPLDL®'s antimicrobial activity against a wide range of clinically important human and/or animal pathogens including Campylobacter, Shigella, Salmonella, E.coli O157, and Clostridium difficile. The results of two published independent human studies in different countries show significant reductions in both blood pressure and cholesterol and the product to be safe and well tolerated. The first study (see hxxps://journals.plo Publications and presentations help differentiate LPLDL® from products which are sold solely on marketing and reduce the risk of commoditisation and price erosion. Regulatory LPLDL® was determined as Generally Recognized As Safe ("GRAS") by an independent expert GRAS panel in the United States. GRAS is a United States Food and Drug Administration (FDA) designation and expands potential applications from supplements to use as a functional ingredient in a wide range of food, dairy, beverage and high value medical food applications. GRAS, and pharmaceutical GMP manufacture validation, creates the potential for LPLDL® to be commercialised as a pharmaceutical drug product, and are major points of differentiation from other probiotics. They increase the market attractiveness of LPLDL® to pharmaceutical partners either used by itself, or as combination treatment to help lower the dose and potential side effects of statins. This extends the opportunity outside the traditional supplement market into broader therapeutic opportunities. Commercial update ProBiotix Health has developed the science, carried out human studies to confirm product safety and efficacy, protected its commercial interests with a broad IP portfolio (~30 patents), and built a supply chain of licensed partners to manufacture, formulate, and distribute product around the world. The company now has partners commercialising LPLDL® in over 60 countries including the world's largest probiotic market (USA: Seed Health) and second largest (Italy: AlfaSigma). The next stage of its strategy is to grow sales with existing partners, extend territories and applications, and continue to sign up new partners. In addition to growing sales, the company is renegotiating contracts as volumes increase to reduce the cost of goods. The renegotiation of our contract with Sacco S.r.l.,(RNS: March 2020) from a profit sharing to a manufacture supply agreement where we buy from Sacco and then sell product to partners significantly improved margins. Of particular note is the growing list of pharmaceutical partners (AlfaSigma, Actial Pharma Akums Pharma) who recognise the value of a natural product with a known mechanism of action, human studies and a portfolio of trademarks and patents which protect their commercial interests. LPLDL® is now building a global brand presence and industry credibility with pharmaceutical companies who sell into the high value hospital, GP, and pharmacy network which typically require a greater level of science and clinical evidence than consumer markets. This takes longer but once established creates a high barrier to entry for other probiotic products which often have little science, no IP and no clinical studies. Outlook The Company is extending the use of LPLDL® into a wider range of applications. These include dairy (RNS: 12 February 2020), anti-aging products, and the development of a cardiovascular health portfolio including a blood pressure (CholBiomeBP) and vascular health product (CholBiomeVH). This will complete a suite of cardiovascular applications of different formulations which should meet the regulatory and market needs of most countries around the world. The Company is also exploring:- i. The potential of LPLDL® for immune health properties after a number of customers have reported reduction in allergies, particularly hay fever ii. The use of LPLDL® in combination with existing treatments such a statins, to help lower dose and reduce side effects, whilst maintaining efficacy iii. The Company has sequenced LPLDL®'s genome and is exploring the genetic predisposition of the strain to impact on a range of health areas iv. The Company has been awarded (subject to contract) a grant to explore the effect of LPLDL® on stress, anxiety, and sleep disorders with Universities in the UK and Europe Mikkel Hvid-Hansen, Commercial Director of ProBiotix Health commented: "The identification, and development of LPLDL® from over 4,000 candidate bacterial strains has followed a systematic discovery programme more akin to pharmaceutical products than probiotics. This has led to a strain with a fully sequenced genome, full GRAS status, pharmaceutical GMP manufacture validation, and published studies on its mechanisms of action and clinical effectiveness. We believe these features are key differentiating factors in today's probiotic market. As the gap between drugs and probiotics developed using these approaches narrows, these so called next-generation probiotics, become closer to the emerging concept of live drug biotherapeutic products." | manc10 |
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