Medical Solutions Share Discussion Threads

[garey_de_angelis] 01/2/2007 08:26

2 years ago MLS was, yes you've guessed it, this price

:-(

[garey_de_angelis] 31/1/2007 14:21

Steve,

ACC up again and rising, could have made more on them in 2 days than you would here

:-D

[garey_de_angelis] 31/1/2007 11:29

dirtysteve,

Pop over to the ACC board and do some research, its a peach and it'll return more than this dog in next 6months

:-D

[dirtysteve] 30/1/2007 22:36

They're graph looks just like MLS. Thats enough to put me off. ;)

[garey_de_angelis] 30/1/2007 09:54

OFF TOPIC,

for all those sat here twiddling thier thumbs ACC is worth a look IMHO.

:-D

[paulo dicanio] 29/1/2007 13:28

Good Point Bartdude ... That is what over the years , MLS have a Great Track Record at doing ! Second To None mate ... Lol

[bartdude] 26/1/2007 20:36

They usually wait until the market is going down to put out anything positive!.

[paulo dicanio] 26/1/2007 15:32

Probably True .

[stevi1111] 26/1/2007 10:55

Spaceparallax.....It's more than likely a private trader / investor who trades with MAN Group (GNI touch perhaps) who sold the 225,000 shares in MLS.

I doubt very much that MAN actually invest in Medical Solutions themselves.

In total MAN Group hold 8m MLS shares (probably on behalf of their clients)

[spaceparallax] 26/1/2007 10:11

Not good to see an Institution reduce.

[paulo dicanio] 25/1/2007 12:08

Hmm ...At the end of the day lets wait and see ! Not too long till wait now till some kind of Results are out anyway . As always time will tell ? Although as we know nothing would surprise us with this stock ? ... Lol

[stevi1111] 25/1/2007 11:18

No new contracts either. That tells you nothing special will be happening to this companies profits in the near-term.

[garey_de_angelis] 25/1/2007 11:15

no LBC news in nearly a year!

[garey_de_angelis] 25/1/2007 08:04

rex,

I'm amazed your still optimistic after all this time

:-D

[rex taurus] 24/1/2007 21:57

There has been a bit more activity lately.

Still think this could still leave us all amazed - one way or the other!
;-)

[cmillar] 24/1/2007 14:01

Paulo - Probably Mid march

[cmillar] 24/1/2007 14:01

Dirtysteve - Thanks I guess.

Sorry you didn't hold out 1 more day!

[paulo dicanio] 24/1/2007 12:30

Are there some results due out soon ?

[lbo] 24/1/2007 11:10

Fact remains they posted an operating prfofit at interims and now seem to be turning the corner in many of its divisions. Even after the sale of Dubai they should be operating profitably and will have 9p in cash.

Would not be surprised if we saw the old bidders back again soon

[lbo] 24/1/2007 10:33

GSK Initiates Head-to-Head Study of Cervical Cancer Vaccines

PR Newswire Europe (inc. UK Disclose) - Jan. 18, 2007

PHILADELPHIA, Jan. 18 /PRNewswire-FirstCall/ -- GlaxoSmithKline announced today the initiation of the first study of its kind designed to compare the immunogenicity of its cervical cancer candidate vaccine, CERVARIX(R), versus Gardasil(R). The primary objective of the head-to-head trial is to compare the immune responses to HPV types 16 and 18 in U.S. women 18 to 26-years-old. Secondary objectives include evaluating the immune responses to HPV 16 and 18 in women 27 to 35-years-old and 36 to 45-years-old. In addition, the study will compare immune responses to other cancer-causing HPV types. Initial study results are anticipated 12 months after study enrollment is completed, and extended follow up will continue for another 17 months.

"Vaccination to prevent cervical cancer may be the most significant healthcare breakthrough for women in our lifetime," said Dr. Mark M. Blatter, Medical Director of Primary Physicians Research in Pittsburgh, PA and study investigator. "This unprecedented trial, which will enroll more than 1,000 women, will provide the first scientific evidence to demonstrate how the two vaccines differ with respect to inducing strong and sustained immune responses in women who may be appropriate for vaccination."

Data published in Vaccine in August 2006 demonstrated GSK's cervical cancer candidate vaccine, formulated with the proprietary adjuvant system AS04, induced higher antibody levels and more robust immune memory response compared to the same HPV vaccine composition conventionally formulated with aluminum hydroxide adjuvant alone. Furthermore, data published in The Lancet in April 2006 provided evidence that GSK's cervical cancer candidate vaccine demonstrated protection up to 4.5 years against persistent infection with HPV 16 and HPV 18 -- the two most common cancer-causing HPV types -- and protection from pre-cancerous lesions. Protection was also demonstrated against infection with the third and fourth most prevalent cancer-causing types of HPV, namely types 45 and 31. Collectively, HPV types 16, 18, 45 and 31 are responsible for approximately 80 percent of cervical cancer cases globally.

"GSK is focused on protecting women from cervical cancer, a devastating disease that often strikes women in the prime of their lives," said Gary Dubin, Vice President, HPV Vaccines, GlaxoSmithKline. "By conducting this study, we hope to further the scientific understanding of the role of strong and sustained immune responses to HPV vaccination for the benefit of all women."

About the Study

This is a Phase III, randomized, observer-blind, multicenter study, to be conducted among 1,042 patients in the United States. There will be two arms of the study, one arm receiving GSK's cervical cancer candidate vaccine, one arm receiving Gardasil(R), and each arm will be stratified by age (18-26 [n=374], 27-35 [n=334], 36-45 [n=334]). The primary objective of the study is to compare GSK's cervical cancer candidate vaccine to Gardasil(R), in terms of immune responses to the two most common cancer-causing HPV types 16 and 18, which are responsible for at least 70 percent of all cervical cancers worldwide, in adult women aged 18 to 26. Secondary objectives will assess immune responses to cancer-causing HPV types 16 and 18 in adult women aged 27 to 35, and 36 to 45 as well as evaluate immune responses to other cancer-causing HPV types. Results are expected 12 months after patient enrollment is complete, with extended follow up continuing for approximately 17 months after the last study visit (month 7 through month 24).

About Cervical Cancer

The American Cancer Society estimates that in 2006, nearly 10,000 women were diagnosed with cervical cancer and nearly 4,000 died from this disease in the Unites States in a single year. After breast cancer, cervical cancer is the second most frequently occurring cancer in women ages 20 to 39 in the United States.

About GlaxoSmithKline's Cervical Cancer Candidate Vaccine

GSK's cervical cancer candidate vaccine was developed to prevent infection and lesions from the two most prevalent cancer-causing types of HPV, specifically HPV 16 and 18. It is formulated with the proprietary adjuvant system, AS04, selected to ensure that this vaccine confers strong and sustained antibody levels over time.

More than 16,000 women worldwide have been vaccinated with GSK's cervical cancer candidate vaccine as part of completed and ongoing clinical trials. Phase III studies are under way in more than 25 countries with more than 35,000 subjects enrolled in ongoing trials.

GSK plans to file a biologics license application for CERVARIX(R) for U.S. Food and Drug Administration review by April 2007 for its cervical cancer candidate vaccine. The company submitted a marketing application review to the European Agency for the Evaluation of Medicinal Products in March 2006. Other international regulatory filings followed in Australia, parts of Asia and parts of Latin America in March 2006.

About GlaxoSmithKline

In the next two to five years, GSK expects to launch more major new vaccines in the United States, for example, a vaccine against rotavirus, an improved flu vaccine for the elderly and a meningitis combination vaccines for various ages, including infants.

GlaxoSmithKline -- one of the world's leading research-based pharmaceutical and healthcare companies-is committed to improving the quality of human life by enabling people to do more, feel better and live longer. For company information, please visit

GSK Biologicals (GSK Bio), one of the world's leading vaccine manufacturers, is headquartered in Rixensart, Belgium, where the majority of GlaxoSmithKline's activities in the field of vaccine research, development and production are conducted. GSK Bio employs more than 1,500 scientists, who are devoted to discovering new vaccines and developing more cost-effective and convenient combination products to prevent infections that cause serious medical problems worldwide. In 2005, GSK Bio distributed more than 1.2 billion doses of vaccines to 165 countries in both the developed and the developing world, an average of more than 3 million doses per day.

[cmillar] 24/1/2007 10:22

lqs - how much of that related to Dubai?

[lqs] 24/1/2007 08:50

In the last accounts central costs are £3M. Thats for the PLC board and other things to support the operating businesses. Seems a hell of a lot. The businesses have to make a 3M operating profit for the group as a whole just to break-even.

[randsys] 23/1/2007 17:18

er........like what?

[lbo] 23/1/2007 16:33

Its time to buy when you see the "sellers" posting. I expect some positive news soon

[spaceparallax] 23/1/2007 12:11

See ya Steve and good luck to you. I'm looking to top-uo in KMR too.