Kuala Innov Share Discussion Threads

[doodlebug4] 05/11/2015 18:16

I've just had a response to the email I sent earlier to Elysium and since it states it's confidential I can't publish it here. The gist of it is that although Elysium agree that the news from Intensity Therapeutics is exciting they feel it doesn't warrant an RNS as the information is already in the public domain.
 
 

[doodlebug4] 05/11/2015 17:55

Thanks wolf, unpaid work seems to be my speciality!

Flashheart, I would hope so. Perhaps part of the problem is the time difference between the USA and this country - otherwise Elysium need to get their act together.

[flashheart] 05/11/2015 17:44

You may well be right db. Possibly an RNS in the morning??????

[wolf9] 05/11/2015 17:29

i think you are doing a great job for them db !

[doodlebug4] 05/11/2015 17:10

Absolutely wolf. I wouldn't have known anything about that news if I hadn't had a look at the Intensity website purely by chance. Perhaps Kuala will release an RNS tomorrow about it. Surely they should keep their shareholders updated.

[wolf9] 05/11/2015 17:00

can only imagine the effect on the share price if intensity was a quoted company and released that news via a rns!

[flashheart] 05/11/2015 15:54

Okay. Thanks for that.

[wolf9] 05/11/2015 15:52

flashheart no exact date but am expecting an update in the next 4 weeks

[flashheart] 05/11/2015 15:26

wolf, do you have an exact date for the report update or approximate time span? Thanks. flash.

[wolf9] 05/11/2015 15:23

hopefully get a good report on all the investments in the forthcoming company report

[keya5000] 05/11/2015 15:19

Doodle email the nomad and the company. Would do it myself but I am out.

[doodlebug4] 05/11/2015 15:10

I'm surprised KUL haven't issued an RNS about this wolf, since they have a stake in Intensity Therapeutics and there is obviously progress being made with the research.

[wolf9] 05/11/2015 15:09

agree db that is an interesting update. I also would be happier with bigger stakes in these companies but of course it all depends on the available funding.I would imagine as more funding becomes available or a sale of one of the assets is realised then more substantial holdings will materialise. bwtfdik and am happy to let the professionals run this company as they see fit

[doodlebug4] 05/11/2015 15:00

Lewis H. Bender, president & CEO of Intensity Therapeutics, remarked, “INT230-6 has
been shown to increase recruitment of immune cells to the tumor micro-environment
after intratumoral administration. When given concurrently with checkpoint inhibitors,
the immune response is even more robust, and in this study resulted in a lasting T-cell
memory specific to the tumor type treated.”

Data being presented show that INT230-6 has significant synergy with anti-PD-1
compounds when given concurrently. Greater than 50% of animals having colon cancer tumors with mean volumes greater than 300mm3 prior to dosing achieved a complete response (CR) compared to no animals that were administered the two checkpoint inhibitors alone. Further, following a rechallenge with cells from the same tumor type, CR animals were able to mount a spontaneous and successful antitumor response and remained tumor-free without additional treatment. This anti-cancer immunity persisted for the life of the animal. However animals depleted of T cells (CD4+ and CD8+) prior to the challenge were unable to mount a successful anti-tumor response.

Mr. Bender concluded, “These experiments further expand our understanding of the
mechanism of action of INT230-6, which appears to induce a robust memory T -cell
response specific for the tumor treated. We look forward to exploring INT230-6 in
clinical studies, which we expect to start in 2016.”

[doodlebug4] 05/11/2015 14:49

Interesting update from Intensity Therapeutics today:

[doodlebug4] 05/11/2015 11:01

There are a few things in the pipeline with Factom at the moment which should come to fruition soon flashheart and I agree that a larger stake in the blockchain concept is a good idea.

[flashheart] 05/11/2015 10:00

......and we need to take a larger stake in it in my opinion.

[doodlebug4] 05/11/2015 09:51

Blockchain is the new "shining star".

[keya5000] 04/11/2015 22:09

Doodle I don't doubt his reputation will open doors other AIM CEOs could only dream of.

[doodlebug4] 04/11/2015 21:59

Mellon has so many forward thinking ideas that I wonder if he will buy small stakes in a few innovative companies to begin with and then wait to see which ones are the most profitable before investing further. A bit like having a portfolio of shares - run the winners and sell the losers. Interesting times ahead here.

[doodlebug4] 04/11/2015 21:40

I agree with you keya, he is a high profile marketing machine and I think he will use his various connections to publicise FastForward Innovations when the new company is launched.