I've bought back in here after quite a while. Looking for diversity and yield - as well as great things. (Time is a great healer .....) Apologies to all longs in advance - my timing is usually poor. |
Any morning gains seem to be routinely reversed with Wall Street opening |
VERY IMPORTANT:
Gepotidacin accepted for priority review by US FDA for treatment of uncomplicated urinary tract infections in female adults and adolescents
Application supported by positive results from pivotal phase III EAGLE-2 and EAGLE-3 trials - 26 March 2025 assigned as action date for FDA decision.
Gepotidacin could be the first in a new class of oral antibiotic treatment for uUTIs in over 20 years. |
We need them to disagree a lot.. |
The US disagree |
Currency movements have also been a headwind. |
Yes, there's been a lot of good news flow all year and the neutral response in the share price seemed to have been attributed to the litigation issue. Now that's gone, there's still some ill sentiment. It will take time, rather than positive news for that to dissolve. |
I must say I feel a lot less bullish after witnessing the very poor share price reaction to the Zantac news. Seems like we need a lot of good news flow before this can get motoring again. |
Many brokers citing 1820 to 1850p (Citigroup 1900p) |
Guggenheim cuts target price to 1785p from 1898p |
Your >25 years dividends (especially if used to buy more GSK as you go) would have been worth a great deal more than the 3% that you are up. Do the calculation and consider continuing with GSK for your income portfolio. |
 Brexit wasn't great for pharma's. We lost the EMEA hq, its harder to attract EU scientists, the contract labs that need to work on a fast turnaround have lost business due to customs delays. We have no say in making regulations but still have meet them (de-regulation in medicine won't happen, we always have to meet EP/USP/JP standards). Perhaps there are some gains, but as someone who visits pharmas regularly I've never been told one.
Pharma regulation needs to cover major populations. Whilst there has been a lot of harmonisation in the cGMP requirements, it would be impractical to introduce our own. It would send the cost sky rocketing. And if we failed to meet others, it simply wouldn't be allowed to be sold. Regulation (particularly data integrity) is here to stay.
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I'm tempted to add more here. I've held GSK as long as I can remember - at least 25 years and I'm up 3%. That excludes dividends. But as I move towards an income portfolio and the clinical news has generally been positive it should hopefully be dull and worthy for the next 25 |
More positive Phase III news:,
GSK announces positive phase III results from ANCHOR trials for depemokimab in chronic rhinosinusitis with nasal polyps
· Primary endpoints met with statistically significant reduction in nasal polyp size and nasal obstruction versus placebo plus standard of care, at 52 weeks
· Depemokimab is an ultra-long-acting biologic administered once every six months
· Patients with chronic rhinosinusitis with nasal polyps (CRSwNP) experience a range of symptoms which are widely underestimated and often sub-optimally treated |
That is the thing. We all need to respect that other people can have alternative views. There are obviously benefits and negatives to EU membership and also Brexit. It is a complicated world. |
.. much more than we gained from exiting.I respect your opinion though, even if I don't agree with it. |
The process of shipping, making and approving medicines has actually been hindered by Brexit. The process of scientific collaboration with Europe has also been restricted. The Johnson government took credit for the Covid vaccines rollout, but in reality this was down to the regulator and the companies.We always had sovereignty, we just also had a minority of decisions that were taken in consultation with the bloc.We also had a lot of regulations (workers, food, environment) that those nefarious backers of Brexit in the background wanted removed in their greed for ever more profits.I grant you that the EU was bloated, slow in decision making and corrupt in places but I've never seen a large governing body that wasn't.Not to mention the 4% PA loss of GDP because of all the trading restrictions.I believe we have lost much, |
Vaccine rollout during the pandemic.Sovereignty over our own affairs. It is therefore our own inept politicians who we can blame for policies.Ability to make our own laws to suit our national strategic intentionsAbility to be more dynamic as we act for our own national interest (unlike the archaic EU decision making process (or lack of).The fact we can still buy lettuces from the Spanish is also a miracle as they were not going to let us buy then of them if we votes the wrong way. We can still breath oxygen.I do not understand why remainers see the EU as some sort of promised land. Vast swathes of people in the EU are desperate to leave it. Economically the EU is in terminal decline. It is certainly not some sort of nirvana. Brexit was also not ever going to be an instant fix and of course the world is work in progress. Covid hit all western countries hard and that happened just after Brexit so hey ho. |
The EU has also been reduced to US vassalage, so the choice was report to Washington directly or via Brussels. |
Still waiting.. and will be, ad infinitumYou can be smug if you want as you got what you wanted. If what you indeed wanted was to accelerate the decline of this country.Anyway, no politician has the stomach to revisit this as, we even see here in microcosm, the debate is still too toxic for now. It's just that there are ever fewer options left for arresting the decline. |
Watching the smug, arrogant and conceated little faces of the Pro EU remainers drop when they realised they had lost in the referendum.... and that the uneducated underclass and misinformed neanderthals had been tricked and lied to in order to vote Brexit. Let's remember that it was only the informed and intellectual people who voted to remain in the blessed EU!! Since the 1980s hay day Europes proportion of the world economy has plummeted. Europe is in terminal decline on the world stage. |
In very simple terms...Someone needs to bid for this basket case and take it out... |
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