Eden Research Share Discussion Threads

[chrischas] 30/11/2024 18:22

Supersonico has been on years before he joined up

[kittybiscuits] 30/11/2024 17:00

Equally, for balance anyone can also see your posts are solely aimed at slagging off everyone who disagrees with your narrow minded one track mind and you have an unhealthy fascination with a company you don’t even invest in. Been doing it for thousands of posts over multiple years!!!

I just suggest people just do their own research!

[neutralpov] 30/11/2024 16:48

NEWCOMERS

Ignore these long spam-like posts (like the ones just made). They are either from a remunerated professional ramper or, as in the case of supersonico, one of a group of desperate trapped bulls hoping to offload. Liars to the last man or woman, and employing dozens of duplicate avatars.

They are here on this DB to distract you from the wholly UNinvestable nature of this pariah of the AIM.

Move along, there's plenty of investable biotechs. This isn't one of them. It is disgusting.

[supersonico] 30/11/2024 09:17

A Canonised Science Platform (CSP) is RedTractor Science (RTS) that builds on given certainties such as anthropogenic climate change and Pandemic preparedness.

Despite much evidence pointing to the science being unsettled and highly contested the CSP instead canonises these issues as being undisputable settled scientific facts and your a heretic if your not fully seduced..

The platform responds to the declared crises by designing a gameable system commercially advantageous to itself and labels detractors as cranks and uses media ,censorship , funding incentives and cancelling to close down debate while euphorically promoting new technological solutions to the system determined existential threats .

Obviously Musk the Edison of our era .. becomes the enemy here as he provides a platform for open debate and free speech which is inconvenient to the high priests of canonised settled science.


An example of this CSP incentive structure can be seen here at the MIT GSW 2023 | Biotechnology Keynote with Greenlight's CEO Andrey Zarur who has no doubt of how the opportunity his technology answers the crisis crafted by the CSP narrative.


On the contrary side of this issue here is a debate between Prof Steve Keen and Dave Collum PHD where both sides of the debate are presented leaving the audience in no doubt that the incentivised scientific certainty that Andrey Zarur speaks of is far from settled but does suit powerful concentrated corporate interests and legacy lap dog forth estate types.

The Ultimate Climate Change Debate | Dave Collum, Steve Keen, & Bill Fleckenstein


Finally one can observe in real time a most peculiar expression of this particular set of corporate Red Tractor Thinking and incentives play out if one closely follows the policies emanating from the economy extinguishing German Green party who would like nothing more than WW3 ..presumably it will be a decarbonised net zero apocalypse they yearn.

[supersonico] 30/11/2024 08:09

Inside The Fall Line venture capital Tent ..aka a Canonised Science Platform.

GreenLight Biosciences Enters into Definitive Merger Agreement with Consortium Led by Fall Line Endurance Fund for Go-Private Transaction

[kittybiscuits] 30/11/2024 01:26

Still banging that same drum Simon? Maybe should call you ‘Simple Simon’ as you do not have a clue.

[neutralpov] 29/11/2024 20:05

Reiterated target SP

EDEN.lon
ZERO PENCE (0.0000p)

The prepack approaches steadily..... :D

[horsepower] 29/11/2024 17:26

Just look at the trades guys. There are constant buys. Ask yourselves why. This is on the up. Fact.

[chrischas] 29/11/2024 17:10

Like the share price too.

[kittybiscuits] 29/11/2024 16:45

Like a stuck record.

[horsepower] 29/11/2024 16:21

Get a life Neuts. Share price up again. Ever sense you might be missing what is right in front of your face ?

[money never sleeps] 29/11/2024 16:08

Cheers Simon!

[supersonico] 29/11/2024 07:24

MNS.. Your welcome.

Summary and main vectors hypothesis;

The problem (1) and the solution in a nut shell below which is why Greenlight Bioscience and Eden are likely partnered (2)and the commentary in the Greenlight video tells us why the collab is dynamite.(3)

supersonico19 Feb '24 - 21:06 - 16914 of 19328 Edit

(1) 'However, compared to many chemical products, biologicals, such as microbial pesticides and RNA biopesticides, still have issues, such as being more vulnerable to environmental conditions and having lower stability. Therefore, biological pesticides have a higher requirement for relevant technologies to protect their active ingredients.




(2) From Ostroff etal and Greenlight Patent ..aka The SustainE solution.

[00023] In some embodiments, the pesticidal polynucleotide inhibits expression of a target gene in a plant pest, optionally wherein the plant pest is an insect. In some embodiments, the pesticidal polynucleotide is a single-stranded RNA (ssRNA) or a double-stranded RNA (dsRNA). In some embodiments, the composition comprises yeast particles and wherein the pesticidal polynucleotide is encapsulated within the yeast particles.

PESTICIDAL COMPOUNDS AND THEIR USE


(3) @ 1 HR 15MIN

Operate effectively in the field with RNA
in this case delivered by our delivery
platform even more exciting I would say and and
working up the the delivery system we made a discovery that the bio capsule
plus certain co-formulants uh can exhibit an increased activity so this is
a little bit of a complex slide what it shows is in the light green bars various treatments that don't have any biocapsule and then in their dark green increasing concentrations of Bio capsule

along with increasing concentrations of the scope formulate so
co-formulant alone the first three uh light green bars you see there's there's
very little activity there and then you add in more code formula and more bio
capsule and you get very good production protection against defoliation so this

was uh really exciting to us because now it suggests that not only not only do we have a platform of delivery where we can deliver RNA we can begin to add in other components to further enhance our
overall activity and best Spectrum in the field another attribute of this system is its ability to reduce the dose response in resistant insects


so you heard earlier that one of the the main things along with residue and registration was to be able to overcome

insect resistance so this is work that's been done in the lab with this particular strain of uh Diamondback moth it's resistant to insecticides a little bit of complex data here to look at but on the left hand upper panel you'll see the bile capsule alone and there's really no mortality there against the dbm and then on the right hand part of that

graph is you increase bile capsule with the co-formulant you know we're achieving up to nearly 100 percent mortality on in insecticide resistant Diamondback moth so that's a really
important Discovery for us if you graph that out and just think about it on the
right hand panel there's a dose response curve shown in Gray so if you take the

skill formula and and do some dose testing and then add in the the bio
capsule you shift that dose response curve to a more sensitive rate that can
be close to two orders of magnitude and then on the bottom part of the graph
if you express that then as a resistance ratio we've lowered the resistance ratio
that is increase the sensitivity from a calculated

number of 151 in this case to about 12. so over 10 fold reduction in
resistance Ratio or increase in susceptibility so now we've got a platform we can deliver RNA we can load
it we can tune it and it's got attributes of overcoming resistance
this has also been shown here in the the greenhouse kind of another intermediate

step in the way but increased bio capsule in dark green along with co-formulant at increasing rate you see
the the decrease in defoliation so more examples of plant protection and then
some pictures on the inside on the right untreated control top right or top left formula
some damage on the middle and then the bio capsule political formula is

essentially clean from from feeding damage it might be a little bit hard to see but that's if you think about the dark spots
on the top onto your control that's what you see a reduction of an elimination of uh with the biotech so plus go Parliament so last slide for me I'll take it back to the beginning of the field data you
know first demonstration of double stranded RNA controlling lepid Opera in the field underpinning that is rnade from a particular sequence that we've worked on for a while now um it's got really good lethality when one treats Diamondback moth cell lines with it and you under look into that

further and you can see the reduction in gene expression indicating rnai is the
mode of action so we've come a long way in the last two or so years with our LEP program it's now got uh the ability to be broadened out Beyond Diamondback moth we've shown these same sort of results with fall army worm and so we'll build out Spectrum as we go forward .

[investingisatrickygame] 29/11/2024 07:12

It doesn't seem as though Green Light is in a great place though. Hardly of the ilk of Corteva, Sipcam, Eastman. With Eden on the up, I'd expect stronger associates/partners

[money never sleeps] 29/11/2024 04:36

For balance Super, I appreicate the Green Light link, which is more obvious now you've spelled it out to me. It seems there must be a connection.

[neutralpov] 29/11/2024 03:51

ROTFLMAO @ the ludicrous goings-on in this Boiler Room.

We'll do our best to ensure they throw the keys away.

[money never sleeps] 28/11/2024 21:54

I do agree with you this time, Super. They're wild guesses, nothing of substance to suggest a 3-week timeline.

Yours truly,
Victor

[horsepower] 28/11/2024 21:45

But they aren't man - just check their posts on other BBs. They're not holding common stocks so clearly are not the same person. Why persist with blatant lies?

[neutralpov] 28/11/2024 20:22

Madwoman supersonico lamely trying to convey she doesn't know moneyneversleeps, kittybiscuits, timbo_slice etc ad nauseam are all one and the same BSing trapped bull.

:D

[supersonico] 28/11/2024 19:25

All wild guesses Kitty but..my thinking is;

Viking video silence across all Eden and Corteva staff suggests bigger launch on the horizon as Investing said.

Background .. Costa 2025+ 'very soon' statements.

First EUA in Italy was 18 Dec 23 but clearly anticipated earlier by both Eden and Corteva by stocking agreement and May 2021 RNS of 2024 planting season goal.

Second Italian EUA comes 7 Nov 24 ..Earlier by 6 weeks than 2023.

So I'm calibrating the 7 Nov EUA as 6 weeks notice roughly on full EU approval.

Sam Eathington commentary @1hr29m in the Corteva Innovation Web cast in referring to EU approvals sounds very confident in Corteva's 'regulatory capacity to get things approved around the world is quite beneficial there'.

Plus anything that I post that MNS rebukes strengthens my conviction that I'm over the target.:)

[kittybiscuits] 28/11/2024 18:42

What makes you think within 3 weeks Super? Anything specific?