Angle Share Discussion Threads

[sicilian_kan] 30/12/2024 01:55

They have not done the molecular analysis, see above and below from the half yearly:

“ Prostate and ovarian cancer studies

Recruitment of participants for the Company's prostate cancer study (DOMINO) and ovarian cancer study (EMBER2) has completed. DOMINO resulted in the collection of >400 blood samples from 100 prostate cancer patients whilst EMBER2 collected >1,400 blood samples from 400 ovarian cancer patients. The blood tubes drawn from each patient have been processed using the Parsortix system and the cell harvest stored for future molecular analysis. ”

[seball] 29/12/2024 21:51

So results of domino study could drop anytime now?

[tbow112] 29/12/2024 20:14

Thanks for the clarification, Bermuda.
Can you explain the lack of progress with DOMINO.

[bermudashorts] 29/12/2024 17:51

tbow112 - that isn't the Domino study. It was a separate study that a particular researcher at Solaris was interested in working on. It was terminated after only recruiting 9 patients. As others have pointed out, the Domino study has fully recruited 100 patients.

[tbow112] 29/12/2024 14:58

Has anyone read the paper arising from the original Barts study which apparently suggested that there was room for improvement with Parsortix ?

[tbow112] 29/12/2024 14:54

This seems to be the original plan for DOMINO but the trial has since been terminated.

[kryptonsnake] 29/12/2024 11:47

From the half year report

"Prostate and ovarian cancer studies

Recruitment of participants for the Company's prostate cancer study (DOMINO) and ovarian cancer study (EMBER2) has completed. DOMINO resulted in the collection of >400 blood samples from 100 prostate cancer patients whilst EMBER2 collected >1,400 blood samples from 400 ovarian cancer patients. The blood tubes drawn from each patient have been processed using the Parsortix system and the cell harvest stored for future molecular analysis."

No mention of Solaris in the RNS



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[kryptonsnake] 29/12/2024 11:40

From Angle website

"The first patients were enrolled into this study in Q1, 2023, with headline results expected in 2024. Compelling data from the DOMINO study could form the basis of a laboratory developed test (LDT) which ANGLE would offer from its clinical laboratories in the US and the UK.

MidLantic Urology, an affiliate of Solaris Health Partners (Solaris), is one of the largest providers of specialist urology services in the US. The Solaris Health network encompasses more than 500 clinical urology providers across 179 locations and nine states treating ~730,000 patients annually."



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[htrocka2] 29/12/2024 11:24

- partnership established with Solaris Health, a major United States urology group to evaluate the Parsortix system in prostate cancer
- clinical study now underway and expected to complete during 2023

[tbow112] 29/12/2024 10:28

Does that not suggest that something has gone significantly wrong with the Solaris project ? Initial results were expected in 2023.
Have I missed some announcement ?

[jelenko] 27/12/2024 21:48

According to Andrew they are. I think they are in the process of selecting the most appropriate downstream analytical system. I understand they have the samples in storage.

[tbow112] 27/12/2024 21:05

Is there any evidence that Angle continues to work with Solaris ?

[gooosed] 27/12/2024 14:36

Associated Urologists of North Carolina Has Joined Solaris Health

"AUNC brings to Solaris the skills and talents of 30 providers who care for over 40,000 unique patients each year. The addition of AUNC means that Solaris now aligns the skills and talents of over 730 providers who annually care for over one million unique patients located in 14 states."

[kryptonsnake] 27/12/2024 13:47

Give it a few months I'll be selling for huge profits



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[willfy] 27/12/2024 13:43

If you were as smart as me, you would have also sold at a huge profit....

[kryptonsnake] 27/12/2024 13:31

If I made near on 300% profit on a stock I wouldn't feel the need to visit the board almost yearly to berate the management

Perhaps you should look to buy in and repeat that win

But I doubt you a smart enough



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[muffster] 27/12/2024 11:24

Probably 698 masquerading. Sad

[willfy] 27/12/2024 11:06

I am not gloating, I have family and friends who are still sadly invested here.Parsortix is an amazing product, it could and should be an absolute game changer when it comes to Cancer diagnosis and capturing CTC.But in my opinion due to AN negligence, it still years away from been used to its full potential.How many life's could have been saved, if only the board had a clear and precise way of getting the product mainstream...

[robizm] 27/12/2024 10:50

Surely you must have something better to do than coming onto this board to gloat? Go and enjoy the rest of the holidays.

[willfy] 27/12/2024 10:40

My average was 19p, bought in about 14 yrs ago, so nice profit for me, whilst I imagine your sitting on a Huge loss, but still defending how the company are handling things.Was very active on this BB for many years, though I'm guessing most of the LTH have also bailed out, hopefully with a profit t

[kryptonsnake] 27/12/2024 10:06

I'm guessing you paid a lot more than 80p for your shares

Your posting history is just you turning up on this board every year to say you sold at 80p

Nobody gives a flying fu*k



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[willfy] 27/12/2024 08:33

Sold out at around 80p mark a few yrs ago, so massive profit whilst you're probably nursing huge losses on your investment, so who's the muppet now !Share price is currently below 10p, so wasn't far out with my prediction.Angle needs a total clear out of the board, AN is clearly out of his depth

[lairddavid] 25/12/2024 12:12

Merry Christmas to all.