Zymeworks Announces Participation in Upcoming Investor Conferences

Zymeworks Inc. (Nasdaq: ZYME), a clinical-stage biotechnology company developing a diverse pipeline of novel, multifunctional biotherapeutics to improve the standard of care for difficult-to-treat diseases, today announced that management will participate in the following upcoming investor conferences:

• Wells Fargo Healthcare Conference: Zymeworks’ management will participate in one-on-one meetings and a fireside chat on September 4 at 8:45 am Eastern Time (ET) in Boston, MA.
• Morgan Stanley 22nd Annual Global Healthcare Conference: Zymeworks’ management will participate in one-on-one meetings and a fireside chat on September 5 at 7:00 am ET in New York, NY.
• H.C. Wainwright 26th Annual Global Investment Conference: Zymeworks’ management will participate in one-on-one meetings and a fireside chat on September 10 at 11:00 am ET in New York, NY.
• 2024 Cantor Global Healthcare Conference: Zymeworks’ management will participate in one-on-one meetings and a fireside chat on September 18 at 3:05 pm ET in New York, NY.

About Zymeworks Inc.

Zymeworks is a global clinical-stage biotechnology company committed to the discovery, development, and commercialization of novel, multifunctional biotherapeutics. Zymeworks’ mission is to make a meaningful difference in the lives of people impacted by difficult-to-treat cancers and other diseases. The Company’s complementary therapeutic platforms and fully integrated drug development engine provide the flexibility and compatibility to precisely engineer and develop highly differentiated antibody-based therapeutic candidates. Zymeworks engineered and developed zanidatamab, a HER2-targeted bispecific antibody using the Company’s proprietary Azymetric™ technology. Zymeworks has entered into separate agreements with BeiGene, Ltd. (BeiGene) and Jazz Pharmaceuticals Ireland Limited (Jazz), granting each exclusive rights to develop and commercialize zanidatamab in different territories. Zanidatamab is currently being evaluated in multiple global clinical trials as a potential best-in-class treatment for patients with HER2-expressing cancers. A Biologics License Application (BLA) to the U.S. Food and Drug Administration (FDA) seeking accelerated approval for zanidatamab as a treatment for previously-treated, unresectable, locally advanced, or metastatic HER2-positive biliary tract cancer (BTC) has been accepted and granted Priority Review. A BLA has also been accepted for review by the Center for Drug Evaluation (CDE) of the National Medical Products Administration (NMPA) in China. If approved, zanidatamab would be the first HER2-targeted treatment specifically approved for BTC in the U.S. and China. Zymeworks is rapidly advancing a deep pipeline of product candidates based on its experience and capabilities in both antibody-drug conjugates and multispecific antibody therapeutics across multiple novel targets in indications that represent areas of significant unmet medical need. In addition to Zymeworks’ wholly owned pipeline, its therapeutic platforms have been further leveraged through strategic partnerships with global biopharmaceutical companies. For information about Zymeworks, visit www.zymeworks.com and follow @ZymeworksInc on X.

Contacts:

Investor Inquiries:

Shrinal InamdarDirector, Investor Relations(604) 678-1388 [e-mail]

Media Inquiries:

Diana PapoveSenior Director, Corporate Communications(604) 678-1388 [e-mail]