Director Shareholding

RNS Number:3073R
Alizyme PLC
24 October 2003


For Immediate Release                                            24 October 2003



                                  ALIZYME PLC
                            DIRECTOR SHARE PURCHASE


Alizyme plc (the "Company") received notification yesterday that the following
Director had become aware of the purchase of an additional 30,464 ordinary
shares of 2p each in the capital of the Company ("Shares") of which he is the
beneficial owner. These Shares were purchased as part of the Placing and Open
Offer completed on 20 February 2003.

Director      No. of      Date              Price    Subsequent   Percentage of
                                                     total
              Shares      purchased         per      beneficial   issued share
              purchased                     Share    holding      capital

William Edge  30,464 (i)  20 February 2003  #0.28   605,566       0.44%
                                 


(i) All 30,464 Shares registered in the name of Rowan Nominees Limited.


For further information, please contact:


Mr Tim McCarthy, Finance Director
Alizyme Plc                                         Tel No: + 44 (0)1223 896000

Lisa Baderoon
Buchanan Communications                             Tel No: + 44 (0) 20 74665000


Further information on Alizyme can be found on the Company's website:
www.alizyme.com






                      This information is provided by RNS
            The company news service from the London Stock Exchange

END
RDSNKQKDABDDKKB