Skinbiotherapeutics Share Discussion Threads

[bobalot] 27/10/2017 11:34

Nice to see loads of buying this morning --- the market is waking up to SkinBio's potential as an antibiotic + medical creams research company for big Pharma.

[shrewdmole] 27/10/2017 11:03

A couple are mine.

The rationale is that I believe Opti are about to turn the corner and see a real surge of interest which in turn will have people looking into Sbtx more.

Could be wrong but I don't think so.

S

[dorset64] 27/10/2017 09:02

Good bit of buying all of a sudden?

[rafboy] 27/10/2017 08:42

Something up, all these 25K buys going through.

[bobalot] 25/10/2017 17:09

aND YOU HAVE NOWT ,,,lol @fatty

[fathenry] 25/10/2017 16:10

you got 3m of these mate, talk about rampong

[bobalot] 25/10/2017 09:07

Probiotics to replace antibiotics in wound healing?

Dr Catherine O’Neill, CEO of SkinBioTherapeutics Plc (LON:SBTX)
'Its worth remembering that penicillin, one of the first antibiotics to be used medically, is derived from a mould. Micro-organisms make antibacterial compounds against each other. Against this background, the hope is that new antibiotics will be discovered in the human microbiome that will help in the fight against antibiotics resistance.’

In a world where antibiotic resistance is becoming a major problem, scientists race in search for alternatives. Could bacteria provide much-needed strategies to prevent life-threatening infections? 

The following article provides valuable insight into this and more: 

[bobalot] 24/10/2017 16:21

The Biotech space is getting attention and the sector is getting hot right now, soon SkinBio will get some lime light.

The Next Hot Biotech Stock… Can It Beat the Biotech Index?

[bobalot] 24/10/2017 14:34

This Biotech space is going to explode as the new Pharma for treatments imo.

[mouse20] 23/10/2017 21:48

Excellent video on the skin microbiome from MIT.

MIT Enterprise Forum San Diego – Sept. 2017 Microbiome



It's fairly long but very relevant to sbtx.
It starts off with a general introduction to the microbiome with Rob Knight before moving onto the skin microbiome and disease prevention. It then focuses on commercialising products from skin microbes. The commercialisation section is with a spin out company from San Diego University at La Jolla. Which is exactly where Optibiotix are at a conference next month.

It looks like the skin microbiome is going to have a great deal of interest- Bill Gates for example. Might have to buy a few more shares here.

[bobalot] 23/10/2017 10:07

The company are researching a new range of antibiotics created by microbes, once amplified will produce a range of antibiotics for BIG PHARMA --- a massive global market awaits SkinBio imo.


SkinBiotherapetics PLC (LON:SBTX) chief executive Cath O’Neil published a study on the potential of skin probiotics as an anti-bacterial when she was working as a senior lecturer at the division of Musculoskeletal and Dermatological Science at the University of Manchester .

In the research, the team from Manchester showed specific types of bacteria could protect skin cells in the laboratory from infection by S. aureus, an infection carried in the noses of 30% of people.
While the skin normally provides a major barrier, during surgery for example it can enter the body with devastating consequences.

[elrico] 22/10/2017 19:03

Market cap to double to c£20-26m...I'll take that bob but I won't be selling ;)

[bobalot] 20/10/2017 11:12

Fair value for SkioBio at this stage is about 17p to 22p before clinical trials start imo.

[shrewdmole] 20/10/2017 11:02

Simple - it's undervalued.

The closer we get to clinical testing and commercial tie up the more the discount to value will close.

Opti and Sbtx are at the forefront of a game changing science.

S

[asterix96] 20/10/2017 09:10

Lots of buying this morning. Wonder why!

[2350220] 19/10/2017 15:18

Nice one bobalot.
Thanks for posting it,
John

[bobalot] 19/10/2017 14:11

EVEN MORE EXCELLENT NEWS ....

Antibiotic concerns highlight Skinbiotherapeutics' infections potential 12:32 19 Oct 2017

The company has been developing products based around the skin portion of the human microbiome

Antibiotics apocalypse on the way?

A very scary picture of a world where antibiotics don’t work anymore was delivered in October by the UK’s chief medical officer.

“The world is facing an antibiotics apocalypse, said Dame Sally Davies, who predicted around 700,000 people a year would die from drug-resistant infections unless major medical advances were made.

SkinBiotherapetics PLC (LON:SBTX) chief executive Cath O’Neil published a study on the potential of skin probiotics as an anti-bacterial when she was working as a senior lecturer at the division of Musculoskeletal and Dermatological Science at the University of Manchester .

In the research, the team from Manchester showed specific types of bacteria could protect skin cells in the laboratory from infection by S. aureus, an infection carried in the noses of 30% of people.
While the skin normally provides a major barrier, during surgery for example it can enter the body with devastating consequences.
Tests against bacterial strains

Skinbiotherpeutics is carrying on this work and now testing to see if its flagship product, Skinbiotix, can prevent the attachment of S.aureus, the most common of skin pathogens, to skin cells.

S.aureus is the casue of a range of infections from relatively mild diseases such as impetigo to septicemia.

Infections can be treated successfully with antibiotics, but resistant strains, such as Methicillin-Resistant Staphylococcus Aureus ("MRSA"), are emerging, Skinbiotherapeutics said.

Tests are for SkinBiotix's inhibitory activity in skin cells against a panel of bacterial strains known to be of importance in Healthcare Acquired Infections (HCAIs).

 Albeit at an early stage compared to the cosmetic programme, good progress has been made, the company said recently.

www.proactiveinvestors.co.uk/companies/news/185884/antibiotic-concerns-highlight-skinbiotherapeutics-infections-potential-185884.html

[bobalot] 19/10/2017 12:58

SkinBio medical creams are highly likely to replace alcohol based creams in Hospitals and clinics to combat pathogens.

THAT IS A MULTI BILLION DOLLAR GLOBAL MARKET -- coming our way as investors.

[bdog51] 18/10/2017 18:38

Skinbiotherapeutics Plc: Probiotics to replace antibiotics in wound healing?

Directors Talk article: Did you know that bacteria have antibacterial properties? Its true.


We spoke to Dr Catherine O'neill CEO of Skinbiotix Plc (LON:SBTX) who said, ‘Its worth remembering that penicillin, one of the first antibiotics to be used medically, is derived from a mould. Micro-organisms make antibacterial compounds against each other. Against this background, the hope is that new antibiotics will be discovered in the human microbiome that will help in the fight against antibiotics resistance.’

In a world where antibiotic resistance is becoming a major problem, scientists race in search for alternatives. Could bacteria provide much-needed strategies to prevent life-threatening infections?

The following article provides valuable insight into this and more:

[fathenry] 18/10/2017 12:01

YOUR a larf

[bobalot] 17/10/2017 14:48

NO, but you sound like an addict...lol

[fathenry] 17/10/2017 13:43

BOBALOT, YOU ondrugs mate only askin

[bobalot] 17/10/2017 12:34

SkinBio's parent OPTI is having a price breakout -- up about 4.4p --- this stock will be catching up again imo.

It won't take much for that to happen with a FREE FLOAT of just 23 million shares.

[bobalot] 17/10/2017 08:16

SkinBio is fully funded for the next two years and commercialisation will start after the first Clinical 3 month trials which are due to start early 2018 --- a commercial partner is already being appointed aiming at a full working deal by the end of next year.

The current three or four projects that have a medical bias are being worked concurrently.

NO EXTRA FUNDING REQUIRED WITH 3.9 MILLION CASH IN THE BANK and increasing IP value for its 18 microbial patents.

[elrico] 16/10/2017 21:54

With thanks to John on the OPTI thread, he did all the work uploading to a fileshare site.

THE BEAUTY OF BIO
WE KNOW PROBIOTICS CAN HELP YOUR
DIGESTION BUT WHAT CAN THEY DO FOR YOUR SKIN
CLAIRE COLEMAN INVESTIGATES

With the hottest health-food books of the year invariably featuring the
word "gut" or "microbiome", we've become quite au fait with probiotics
and looking after the "good bacteria" in our stomachs. The latest figures
suggest that whether we're popping a supplement after a course of antibiotics, replacing our regular yoghurt with Activia, or even making our own kefir and kimchi, we're more pro-probiotics (sorry) than we've ever been before. But what about "good" bacteria in your skincare? Could the technology that gives us a healthy gut also be the answer to our dreams of a clear, glowing complexion? Brands such as Aurelia Probiotic Skincare and Gallinee, with its "skincare for the microbiome", think so. The mainstream brand Clinique has also jumped on the band- wagon, with its Redness Solution range that contains "probiotic technology", while Vichy, Niod and La Roche-Posay are all using probiotic and prebiotic ingredients.

Skin conditions such as rosacea and acne seem most likely to benefit from
probiotic technology, but there is increasing evidence that the secret
to anti-ageing could, in part, be down to keeping the bacteria on your skin happy. Recent research shows that the number and type of bacteria in the microbiome of healthy skin is different to that of skin affected by acne, eczema, psoriasis and other types of inflammation. One theory is that if we tinker with the microbiome, making it more like that of healthy skin, we could get rid of certain skin conditions and even slow the rate at which it ages, as that is related to inflammation, too. Only, of course, it's not that simple.

"Keeping bacteria alive in a cosmetic cream is hard," says Dr. Catherine
O'Neil, senior lecturer in clinical biochemistry in the dermatological sciences
research group at the University of Manchester. "Even if it weren't, we don't know
if it would be safe to apply live bacteria to potentially compromised skin."
Instead, what most of these skincare companies are doing is creating extracts that
have the same effects as live bacteria. "The microbiome changes the skin because molecules in the bacteria send messages to the body. But these signaling molecules can still be present in a 'dead' extract," O'Neil says. "We have found an extract that can strengthen the skinbarrier, exclude pathogens and heal skin in the same way the original bacteria can." Her findings will form the basis of products created by the SkinBio Therapeutics brand in the future.


According to Elisa Simonpietri, head of science at Vichy, that's exactly how one of
the strengthening, hydrating ingredients in its Slow Age range works. It is made by
fermenting a type of bacterium called Bifidobacterium longum and, though no
longer live, "it still has the properties of the original bacteria". You will find the same ingredient in Aurelia Probiotic Skincare and in Lancome Genifique Serum.
Elsewhere derivatives of another type of bacterium, Lactobacillus, which
have the same anti-inflammatory action as the live bacteria, are found in
Gallinee's microbiome-focused skincare a nd in the "probiotic technology" of the
Clinique Redness Solutions range. So what about prebiotics? The main thing you need to know is that "prebiotics selectively feed the 'good' bacteria", says Marie Drago, founder of Gallinee. "We use ingredients that are known to have this effect on the bacteria in the gut, but have also been shown to do the same in skin." And her company isn't the only one making these claims. Niod's new Survival serums use a similar prebiotic complex", the La Roche¬Posay Toleriane range is another brand that boasts "prebiotic thermal water", and both Oskia and Ren offer products containing
prebiotics. However, there is still a lot we don't understand about the bugs on our skin. "Many of these probiotic and prebiotic products have active ingredients that have yet to be independently proven," says Nausheen Qureshi, a biochemist who helps
facialists and doctors create skincare products. "We know they help to enhance
hydration and bolster the skin's protective barrier, but it doesn't follow that that's as a result of their impact on the microbiome." Like O'Neil, she points out that pH may have a bearing — "skins with rosacea or acne have a different pH to normal skins" — and suggests it's possible that it is the pH of the probiotic and prebiotic products that could be having an effect. The takeaway? Probiotic and prebiotic skincare could well be beneficial for all of us, whatever our age or skin type, even if it's just for souped-up moisturising — but for now it is only one part of the solution, not a magic bullet.