Premier African Minerals Share Discussion Threads

[mike_f] 07/10/2017 16:50

I agree DT, I'm just trying to be more conservative after recent events and additional shares in issue to churn along the way. Even 1p is still a 200% increase from current levels! Not bad for a few months hold...

[goodgrief] 07/10/2017 13:42

KoP, at least none of the assets are diamond mines or the Mugabes would be filling their pockets...

[merill] 07/10/2017 12:36

2 us biggies are buying Motif (MTFB). Both bought 5% each in 2 days.
Merrill Lynch


Good news hit the wires this morning from Motif Bio (LSE: MTFB), a clinical-stage biopharmaceutical company aiming to develop novel antibiotics. The market likes it and the shares are around 36% higher as I write.
The excitement surrounds details of a positive topline result from a global Phase 3 clinical trial called REVIVE-2, which is focused on the firm’s investigational drug candidate iclaprim for patients with Acute Bacterial Skin and Skin Structure Infections (ABSSSI).


A new drug is born
Chief executive Graham Lumsden tells us that today’s positive results mean the company has completed the two required Phase 3 trials in ABSSSI necessary to submit a new drug application to the US Food and Drug Administration (FDA), which Motif Bio plans to do by the end of the first quarter of 2018.
According to medical experts, ABSSSI is a serious infection and every year around 3.6m people in the US are hospitalised with it for several days. The problem with existing treatments is that they tend to be toxic to the kidneys and that’s bad because around 26% of those suffering with ABSSSI also have kidney disease. Happily, during the trial, kidney toxicity was not observed with iclaprim.
The hope now is that Iclaprim may prove to be “an important option for the growing population of patients with ABSSSI and kidney disease who need a safe and effective antibiotic targeting Gram-positive bacteria, including MRSA.” Meanwhile, from an investing point of view, the outcome of the trial means that Iclaprim now has value, which Motif Bio may be able to commercialise down the road.


Motif Bio presents drug trial data
6th October 2017 08:16 | Motif Bio Plc Ord 1p
Motif Bio has presented new pre-clinical data regarding its investigational drug candidate iclaprim to the IDWeek 2017 conference in San Diego.

"The data presented today underscore the potential utility of iclaprim in a range of patient populations with suspected MRSA infections, including cystic fibrosis patients with Staphylococcus aureus lung infections," Motif Bio chief medical officer David Huang said.


At 8:16am: (LON:MTFB) Motif Bio Plc Ord 1p share price was +0.25p at 43.75p





Merrill Lynch Ups Motif Bio Stake Following Iclaprim Results (ALLISS)
By Alliance | Fri, 6th October 2017 - 14:19

LONDON (Alliance News) - Merrill Lynch International has raised its stake Motif Bio PLC under a transaction on Wednesday and now holds 5.038% interest in the pharmaceutical company.
The purchase came on the same day Motif Bio reported positive results from its phase III clinical study of flagship antibiotic Iclaprim. Iclaprim met its primary endpoint in the phase III trial in patients with acute bacterial skin and skin structure infections, which was non-inferiority whilst compared to the standard of care vancomycin.
Earlier today, Motif Bio released new pre-clinical data showing positive results regarding the use of Iclaprim. In an in vivo model mimicking the pathophysiology observed in cystic fibrosis patients, rats were dosed with either 80 or 60 milligrams of Iclaprim, 50 mg of Vancomycin, and a placebo.
The Iclaprim rats showed a 100% survival rate, 33 out of 33, while Vancomycin showed 92% survival rate and the placebo 48%.
Merrill Lynch had a holding that was below the notable threshold prior to the purchase.
Motif Bio shares were up 6% on Friday at 46.11 pence.
By Joshua Warner; [e-mail]; @JoshAlliance
Copyright 2017 Alliance News Limited. All Rights Reserved.


Motif Bio PLC Holding(s) in Company
05/10/2017 9:57am
UK Regulatory (RNS & others)


TIDMMTFB
RNS Number : 8030S
Motif Bio PLC
05 October 2017

NOTIFICATION OF MAJOR HOLDINGS
-----------------------------------------------------------------------------------------------------

1a. Identity of the issuer MOTIF BIO PLC
or the underlying issuer
of existing shares to which
-----------------------------------------------------------------------------------------------------
% of voting % of voting Total of Total number
rights attached rights through both in % of voting
to shares financial (8.A + 8.B) rights of
(total of instruments issuer(vii)
8. A) (total of
8.B 1 + 8.B
2)
---------------------- -------------------------- ---------------- ---------------- -------------
Resulting
situation
on the date
on which
threshold
was crossed
or reached 5.03% 5.03% 13,257,448





3. Details of person subject to the notification obligation(iv)
Name SAND GROVE CAPITAL MANAGEMENT
LLP
City and country of registered LONDON, UK
office (if applicable)
4. Full name of shareholder(s) (if different from 3.)(v)
-----------------------------------------------------------------------------------------------------
Name SAND GROVE OPPORTUNITIES
MASTER FUND LTD

[donald tramp] 07/10/2017 10:48

I don't think we would need all of those to hit 1p+ Mike, further good assays and PEA should move us to that level. I think RHA profitable at predicted levels is worth about 1.5p in it's own right easily.

[mike_f] 07/10/2017 10:34

Ok F3rdinand, then why was the share price at .4p when it should have been .8p+ etc, it’s because financing has been a bit of a disaster of late and that ultimately comes down to GR! If PB was done in the first instance when the share price was .7p+ I don’t believe we would currently be at these levels.

Having said that, I believe that is now in the past, we don’t have YA or Darwin (for much longer) involved with lots of warrants etc, as soon as the current placing shares are all absorbed (personally I think we are nearly there) then the price will start to move up in anticipation of news.

I still think we could hit 1p+ before Christmas on great assays, a very positive PEA and RHA hitting full production. If a JV occurs before Santa comes I see a lot more than 1p if everything else has fallen into place nicely! Very exciting quarter ahead with the financing issues now in the past. GLA

[turbotrader2] 07/10/2017 09:46

I think the assays will come as early as Monday or Tuesday hopefully Tuesday when the placees have sold for a 5% profit

[andrewsr] 07/10/2017 09:13

The 'delay' in getting the assays back must affect the timing of the PEA, so perhaps a bit longer than GR anticipated in September.

[f3rdinand] 07/10/2017 07:59

The share price isn't 0.3p because of lack of confidence in GR; it's because there has been a placing of nearly a billion shares that Darwin have been offloading aggressively! These shares are being lapped up by PI's so it's unfair to summise investors have lost confidence! When they clear (early next week at a guess) I would expect a large rise as the market cap in no way reflects the assets and potential that PREM has! IMHO

[mike_f] 06/10/2017 21:45

Because confidence in GR was knocked markth126, as soon as the positive news starts to flow the share price will start to reflect true value again IMO.

[markth126] 06/10/2017 21:38

So all these good posts why are we only 0.3p?

[jungmana] 06/10/2017 21:36

Worth listening to again. Zulu PEA could be out in 3 weeks time based on Georges timeline from this interview of 5th September.

[ihavenoclue] 06/10/2017 21:25

napom ... have you heard of paragraphs ?

[napom] 06/10/2017 21:21

Great post from gardeneye on lse..Like many others on here I've been following the PREM story for years. There were 4 reasons I originally invested and these still apply. 1) Circum Minerals. Even 2% was a game changer for PREM back then for the size and quality of the resource. Now 5%, it more than doubles that. It is easy to underestimate just how big, how cheap to produce and how well located Circum is for the Asian and African markets. Potash prices are once again turning around - my suspicion is that this is the time for it to be sold, when on the rise and not on it's knees. It can sell or be listed at any time. News will come out of the blue. My estimate based on the similar projects adjacent is that this will yield PREM $50m. 2) RHA. I liked RHA because it had a good historical record of production. I like Tungsten as a commodity. The whole project has been a nightmare starting with the plummeting price of APT from 450 to 150 that effectively bankrupted the entire industry. It is almost entirely due to this that the share price and the confidence in PREM and the shares in issue went out of control, diluted to death. In many ways, to have built the mine and plant in the worst possible economic climate is nothing short of miraculous and I applaud the Company for persevering. There was a very real chance PREM would have gone under had they not. APT (Tungsten) is notoriously difficult to manage. Being the second hardest mineral on the Planet it is extremely abrasive. To build this for circa $25m is also impressive. The equivalent plant and mine at Wolf Minerals cost 10x this. The breakeven point about half theirs also. When it produces 4% of the Worlds APT, this will be a fairly amazing 'against all odds' type achievement. Depending on APT ($320mtu currently and I expect it to go to $500) -Yield circa $1.25m/ month Q1 2018, plus $25m to be paid back to PREM through profits. 3) Zulu. I hunted for the cheapest possible Lithium mine I could find 3 years ago having bought into the Lithium revolution at the birth of the Tesla story which I devoured, seeing it as a fully feasible alternative to the combustion Engine. I liked their previous exploration results. That initial hunch on lithium seems to be good un. It is hardly possible to find a serious carmaker NOT committed to EV's in the next decade. The LiO energy storage industry is on the cusp of a revolution. There is simply not enough of the correct Lithium grade needed for this. The squeeze on Lithium in about 1 year is irresistible. Drill, drill and hold for this reason is precisely the right thing to do. It's an extraordinary resource and asset for PREM at this time. 4) Unlike a great deal of AIM outfits I also invested in the fact that the CEO had such a massive holding. Skin in the game is important to me. I met the team and liked their experience. PREM really is (after a hell of a long time) FINALLY worth having a serious look at. I wish I had found debt free PREM now rather than 3 years ago.

[gaddy88] 06/10/2017 21:07

Topped up again today on what I hope was the bottoming out. Should be a fairly good run up to Christmas with new due on many fronts. GLA.

[donald tramp] 06/10/2017 21:01

Copied

THEN & NOW

Like many others on here I've been following the PREM story for years.
There were 4 reasons I originally invested and these still apply.
1) Circum Minerals. Even 2% was a game changer for PREM back then for the size and quality of the resource. Now 5%, it more than doubles that. It is easy to underestimate just how big, how cheap to produce and how well located Circum is for the Asian and African markets. Potash prices are once again turning around - my suspicion is that this is the time for it to be sold, when on the rise and not on it's knees. It can sell or be listed at any time. News will come out of the blue. My estimate based on the similar projects adjacent is that this will yield PREM $50m.
2) RHA. I liked RHA because it had a good historical record of production. I like Tungsten as a commodity. The whole project has been a nightmare starting with the plummeting price of APT from 450 to 150 that effectively bankrupted the entire industry. It is almost entirely due to this that the share price and the confidence in PREM and the shares in issue went out of control, diluted to death. In many ways, to have built the mine and plant in the worst possible economic climate is nothing short of miraculous and I applaud the Company for persevering. There was a very real chance PREM would have gone under had they not. APT (Tungsten) is notoriously difficult to manage. Being the second hardest mineral on the Planet it is extremely abrasive. To build this for circa $25m is also impressive. The equivalent plant and mine at Wolf Minerals cost 10x this. The breakeven point about half theirs also. When it produces 4% of the Worlds APT, this will be a fairly amazing 'against all odds' type achievement. Depending on APT ($320mtu currently and I expect it to go to $500) -Yield circa $1.25m/ month Q1 2018, plus $25m to be paid back to PREM through profits.
3) Zulu. I hunted for the cheapest possible Lithium mine I could find 3 years ago having bought into the Lithium revolution at the birth of the Tesla story which I devoured, seeing it as a fully feasible alternative to the combustion Engine. I liked their previous exploration results. That initial hunch on lithium seems to be good un. It is hardly possible to find a serious carmaker NOT committed to EV's in the next decade. The LiO energy storage industry is on the cusp of a revolution. There is simply not enough of the correct Lithium grade needed for this. The squeeze on Lithium in about 1 year is irresistible. Drill, drill and hold for this reason is precisely the right thing to do. It's an extraordinary resource and asset for PREM at this time.
4) Unlike a great deal of AIM outfits I also invested in the fact that the CEO had such a massive holding. Skin in the game is important to me. I met the team and liked their experience.
PREM really is (after a hell of a long time) FINALLY worth having a serious look at. I wish I had found debt free PREM now rather than 3 years ago.

[markth126] 06/10/2017 20:06

Just what are the downsides here? What are people's thoughts on that, upside is obvious but limited downside I would say?

[sleveen] 06/10/2017 18:24

If you drill, results will come.

(To paraphrase the title of a rather good film.)

[the bull] 06/10/2017 17:23

Dreams is all I have at the moment, lets see, come on George give us some solid news

[kop202] 06/10/2017 17:00

Bull you will be rich!......but only in your dreams

[the bull] 06/10/2017 16:32

I have 5M does that make me a big hitter, will I be rich beyond my wildest dreams

[cambradjones] 06/10/2017 16:28

Just bought a few more paid 0.31, happy with that. Buy/ sell spread way out.Hoping the good news starts monday as i have a lot of ground to recover.Gla.

[dingo75] 06/10/2017 15:33

Plan is to sell it to a larger entity ( Zulu ) once they have Jorc'd up or are likely to Jorc up 100mt. Hopefully keeping a 10% free carry. ;)

[kop202] 06/10/2017 15:28

AndrewJoking.....I was referring to my earlier tongue in cheek postsThanks for your views

[kop202] 06/10/2017 15:15

Andrew, joking aside but how long do you think it will be before the stuff is taken out the ground?