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Share Name | Share Symbol | Market | Type | Share ISIN | Share Description |
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Phynova | LSE:PYN | London | Ordinary Share | GB00B0YBCM49 | ORD 1P |
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Posted at 07/7/2009 14:54 by double6 Well - we're now down to a MC of around £600k.Recent share placing at 6p (with warrants at 10p) - currently 2.375p! Will those who took up the placing be regretting things ?? |
Posted at 03/12/2007 09:54 by mal124 Phynova Group plc (AIM: PYN), the developer of prescription pharmaceuticals derived from Chinese botanical medicines, today announces that its Business Development Director, Dr Tony Mills, will provide an update on its plant-derived antibacterial PYN6 at the natural products conference "Natural Products in Drug Discovery and Development" at the Holiday Inn, Munich City Centre on Tuesday, 4 December. Results from pre-clinical work conducted by Phynova in collaboration with the University of East London have demonstrated a high degree of bacterial inhibition against 30 common strains of methicillin-resistanPhynova is conducting formulation studies to develop a topical gel, cream or ointment containing PYN6 as active ingredient and is in active discussions with several companies in the dermatological sector regarding the future development and commercialisation of PYN6. Robert Miller, Phynova's CEO, said: "Gaining access to potentially valuable new drug opportunities such as PYN6 was an important part of the rationale for our cooperation with our Chinese partner Botanic Century. We are delighted that the extensive preclinical work that we have carried out this year has confirmed its promise as a potential treatment for MRSA, the devastating bacterial infection that has become such a problem in the UK. An additional key part of our commercial strategy is to offer a proportion of our drug candidates as in licensing opportunities to the pharma industry so we are also very pleased with the interest that we are attracting from potential partners." |
Posted at 30/1/2007 12:54 by barefoot1 Phynova Appointment of ChairmanRNS Number:2620Q Phynova Group PLC 29 January 2007 For Immediate Release 29 January 2007 PHYNOVA GROUP PLC Appointment of Karl Watkin as Chairman Phynova Group PLC ("Phynova" or the "Group") (AIM: PYN), a developer of pharmaceuticals derived from Chinese botanical drugs targeting viral and metabolic diseases and cancer, is pleased to announce the appointment of Karl E Watkin MBE as Chairman. Karl, appointed as Non-Executive Director on 14 December 2006, replaces John Pool who will continue to act as a Non-Executive Director on the Board. Both appointments are effective immediately. Karl brings to the role of Chairman over 25 years experience working in China, a market critical to Phynova's business strategy and extensive public company experience. Until earlier this month, Karl was Chairman of D1 Oils plc, a UK-based global producer of biodiesel, for which he is the founder and received an MBE for his services to UK exports in 1993. He will remain on the Board as a Non-Executive Director of D1 Oils. Other current directorships include Non-Executive Director of China Goldmines plc, a gold resource company with a direct interest in a gold mining project in the province of Hunan China. Karl also brings valuable expertise gained from the healthcare sector via Dermasalve Sciences plc, a developer of retail dermatology products, which he created in 2004, floated in January 2006 and currently serves as a Non-Executive Director. John Pool has served as Chairman since February 2005, in which time Phynova has progressed from an early stage private company to an acquisitive publicly listed company. Robert Miller, Chief Executive of Phynova, commented: "We are delighted that Karl has become Chairman of the Board. He brings a great deal of public company and Chinese experience which will be of great value to the Company as it progresses through clinical trials this year and further develops its Chinese operations. John is an invaluable asset to the Company and I wish to thank him for all his hard work in moving the Company forward. We are pleased that the Company will retain his expertise as Non-Executive Director." Karl Watkin, Chairman of Phynova, commented: "With the recent acceptance of its IND application to commence clinical trials of PYN17 for Hepatitis C and the acquisition of Botanical Century in China last year, Phynova is gaining momentum in both its drug pipeline and expansion into the Chinese market. As such, it is a very exciting time to be taking up the role of Chairman. I hope that through my experience in China, I will be able to build on this momentum." |
Posted at 12/7/2006 07:16 by grupo Phynova applies for patents for Chinese herb drugs for obesity, hepatitis CLONDON (AFX) - Phynova Group PLC, which develops pharmaceuticals from Chinese medicines, said it has filed patent applications for its PYN-22 drug for obesity and its PYN-18 drug for hepatitis C. And it said it has signed a letter of intent with a clinical research organisation to start Phase IIb trials of its lead development product, PYN-17 for hepatitis C. Chief executive Robert Miller said the company has also strengthened its management team by appointing Stephen Marshall as chief operating officer and David Galloway as chief medical officer. newsdesk@afxnews.com lam/jm |
Posted at 16/5/2006 06:08 by rickus Phynova Group PLC16 May 2006 For Immediate Release 16 May 2006 Phynova Group PLC Interim Results For the Six Months Ended 31 March 2006 Phynova Group PLC ('Phynova' or the 'Group') (AIM : PYN), a developer of pharmaceuticals derived from Chinese botanical drugs targeting viral and metabolic diseases and cancer, is pleased to announce maiden interim results for the six months ended 31 March 2006. Key Points: Successful flotation on AIM in February 2006 having raised £3.65 million via a placing In-license of PYN22, drug candidate targeting obesity Positive outcome from pre-clinical testing on PYN18, drug candidate targeting the Hepatitis C Virus (HCV) Additional source of future revenues from a collaboration agreement with WellGen, Inc. for development of Phynova compounds as nutrigenomic ingredients for functional foods John Pool, Chairman of Phynova, commented: 'Our successful flotation is a major stride forward for the Company enabling us to concentrate fully on the development of our product pipeline. We believe that the following six months will be an equally exciting period for the Company in terms of its development and we look forward to updating shareholders on our progress.' For further information, please contact: Phynova Group PLC Robert Miller, Chief Executive 01865 784880 Nabarro Wells Marc Cramsie, Director 020 7710 7400 Buchanan Communications Tim Anderson/Isabel Podda/Amy Rajendran 020 7466 5000 Chairman's and Chief Executive's Review We are delighted that our introduction to AIM on 27 February 2006 saw the Company advance its development through a pre-IPO placement, which raised £3.65 million before expenses. This has allowed Phynova to concentrate on the development of the most advanced products in its pipeline with a view to moving them into clinical trials within twelve months. Strategy We have established a business model which seeks to reduce the risks, the high cost and the time taken to develop pharmaceuticals by selecting drug candidates which are not only derived from existing medicines with proven safety and efficacy in clinical use in China but also which target large therapeutic markets in the West where current therapies are either inadequate or non-existent. We aim to license our intellectual property to major pharmaceutical companies in return for revenue in the form of upfront payments, milestone payments and royalties. We have identified a number of drug candidates in the fields of anti-virals, anto-microbials, anti-inflammatories and oncology and are currently focusing on the rapid development of six of these. o PYN17 for relief of the symptoms of chronic hepatitis C (CHC) o PYN18 for hepatitis C virus (HCV) o PYN22 for obesity o PYN7 for cancer o PYN6 for antibiotic-resistant bacteria o PYN5 to treat respiratory tract infections Portfolio Update Since our admission to AIM we have continued to work on the development of our intellectual property both existing and new. In April we were pleased to announce the positive outcome from third party testing on PYN18, a novel anti-viral discovered by Phynova's scientists has shown definite in vitro activity against the hepatitis C virus. Since announcing these results we have seen significant interest regarding potential partnerships to drive PYN18 through clinical development. HCV has infected more than 200 million people worldwide and current therapies are often ineffective with negative side-effects. We are also pleased to announce that the Company has entered into a Collaboration Agreement with WellGen, Inc., a life sciences company using nutrigenomics to discover and develop ingredients for functional foods. This agreement gives us an exciting opportunity to generate additional revenues from our research activities. Under the terms of the agreement Phynova will supply WellGen with sample compounds that demonstrate anti-inflammatory activity from its existing pipeline, then work to develop these as functional food ingredients. If successful, royalties will provide a revenue stream in addition to those from our core business. The size of the functional foods market, according to MarketResearch.com, is expected to grow to $167 billion globally by 2010. During the period, good progress has made on the other products in your Company's pipeline, including the in-licensing of a promising new drug candidate (PYN22) for the anti-obesity market which is estimated to be worth $5 billion. Financial Review In the six months ended 31 March 2006, Phynova recorded a pre-tax loss of £597,000, which is in line with expectations. Cash outflow before financing was £609,000 reflecting the loss for the period. Our cash position remains strong and at 31 March 2006 was £2.9 million following our successful pre-IPO fund raising. We are pleased to confirm that we continue to make good use of cash resources and that we remain firmly committed to our budget. Summary and Prospects The progression of our product portfolio has been very encouraging. PYN18 has clearly demonstrated its potential in all initial testing and we anticipate taking this candidate into clinical development as rapidly as possible. Our pre-clinical development program is very active and several of our drug candidates are the subject of on-going screening work by third parties and we look forward to announcing the results in due course. We would like to thank all our shareholders, both existing and new, for their support. We look forward to the next six months in which we will continue to make significant strides in the further development of our product pipeline. John Pool Robert Miller Chairman Chief Executive Officer PHYNOVA GROUP PLC CONSOLIDATED SUMMARISED PROFIT AND LOSS ACCOUNT For the six months ended 31 March 2006 6 months 6 months 15 months Ended Ended Ended 31 March 2006 31 March 2005 30 September 2005 Note Unaudited Unaudited Audited £'000 £'000 £'000 Turnover - - - Cost of sales - research and development (160) (111) (243) Gross Loss (160) (111) (243) Administrative expenses Administrative expenses (315) (139) (364) Aim Listing expenses (130) - - Total administrative expenses (445) (139) (364) Operating loss (605) (250) (607) Interest receivable 8 - - Loss on ordinary activities before and after taxation (597) (250) (607) Basic and diluted loss per share 2 (6.5p) (3.7p) (8.7)p All amounts relate to continuing operations. There were no recognised gains or losses other than the loss for the financial period. PHYNOVA GROUP PLC CONSOLIDATED SUMMARISED BALANCE SHEET AS AT 31 MARCH 2006 At At At 31 March 2006 31 March 2005 30 September 2005 Note Unaudited Unaudited Audited £'000 £'000 £'000 Fixed assets Tangible assets 3 2 2 Current assets Debtors 215 58 204 Cash at bank and in hand 2933 105 29 3148 163 233 Creditors: amounts falling 217 224 217 due within one year Net current assets/(liabilities) 2931 (61) 16 Total assets less current liabilities 2934 (59) 18 Provision for liabilities and charges (236) (94) (236) Net assets/ (liabilities) 2698 (153) (218) Capital and reserves Called up share capital 148 71 76 Share premium account 3860 226 419 Merger difference reserve 642 642 642 Profit and loss account (1952) (1092) (1355) Shareholders' funds/(deficit) 3 2698 (153) (218) PHYNOVA GROUP PLC CONSOLIDATED SUMMARISED CASH FLOW STATEMENT AS AT 31 MARCH 2006 6 months 6 months 15 months Ended Ended Ended 31 March 31 March 30 2006 2005 September 2005 Note Unaudited Unaudited Audited £'000 £'000 £'000 Net cash (outflow) from operating activities 4 (615) (178) (453) Returns on investments and servicing of - - finance Interest received 8 - - Net cash inflow from returns on investments and servicing of finance 8 - - Capital expenditure and financial investment Purchase of tangible fixed assets (2) - (1) Net cash (outflow) from capital expenditure and financial investment (2) - (1) Cash outflow before financing (609) (178) (454) Financing Issue of ordinary share capital 3733 231 429 Share Issue expenses (220) - - Net cash inflow from financing 3513 231 429 Increase in cash 2904 53 (25) NOTES TO THE INTERIM STATEMENT For the six months ended 31 March 2006 1. BASIS OF PREPARATION The consolidated interim financial statements have been prepared in accordance with applicable accounting standards and under the historical cost convention. The principal accounting policies of the group have remained unchanged from those set out in Phynova Group plc 2005 financial statements except for the adoption of FRS21 'Events after the balance sheet date' and FRS 25 'Financial instruments: Disclosures and Presentation'. 2. LOSS PER SHARE The calculation of the basic and diluted loss per share is based on the loss on ordinary activities after tax and on the weighted average number of ordinary shares in issue during the period. The loss and weighted average number of shares used in the calculations are set out below: Basic and diluted loss Loss Weighted average Loss per share per share £'000 number of shares pence Six months ended 31st March 2006 (597) 9,232,227 (6.5) Six months ended 31st March 2005 (250) 6,684,505 (3.7) 15 months ended 30th September 2005 (607) 6,952,913 (8.7) 3. RECONCILIATION OF MOVEMENTS IN SHAREHOLDERS' FUNDS/ (DEFICIT) 6 months 6 months 15 months Ended Ended Ended 31 March 2006 31 March 2005 30 September 2005 Unaudited Unaudited Audited £'000 £'000 £'000 Loss for the financial period (597) (250) (607) Issue of ordinary share capital 72 5 10 Premium on shares issued during the period net of expenses 3441 226 419 Net increase (decrease) in shareholders' funds/(deficit) 2916 (19) (178) Shareholders' funds/ (deficit) at beginning of period (218) (134) (40) Shareholders' funds/ (deficit) at end of period 2698 (153) (218) NOTES TO THE INTERIM STATEMENT continued For the six months ended 31 March 2006 4. NET CASH INFLOW / (OUTFLOW) FROM OPERATING ACTIVITIES 6 months 6 months 15 months Ended Ended Ended 31March 2006 31March 2005 30 September 2005 Unaudited Unaudited Audited £'000 £'000 £'000 Operating (loss) (605) (250) (607) Depreciation 1 1 2 (increase) in debtors (11) (53) (199) Increase in creditors - 30 115 Increase in provisions - 94 236 Net cash (outflow) from operating activities (615) (178) (453) 5. RECONCILIATION OF NET CASH FLOW TO MOVEMENT IN NET FUNDS 6 months 6 months 15 months Ended Ended Ended 31 March 2006 31 March 2005 30 September 2005 Unaudited Unaudited Audited £'000 £'000 £'000 Increase / (decrease) in cash in the period 2904 53 (25) Movement in net funds 2904 53 (25) Opening net funds 29 52 54 Closing net funds 2933 105 29 6. FINANCIAL COMPARATIVES The comparatives for the 15 month period ended 30 September 2005 are not the Company's full statutory accounts for that period. A copy of the statutory accounts for that period was delivered to the Registrar of Companies. The auditors' report on those accounts was unqualified and did not contain a statement under section 237(2)-(3) of the Companies Act 1985. This information is provided by RNS The company news service from the London Stock Exchange |
Posted at 28/2/2006 20:53 by outsider Shares in newly-listed Phynova fell 12.5p to 120p on their second day of trade. Monisha Varadan of leading IPO website allnewissues.com had suggested that the shares were overvalued. The alternative drugs company, which specialises in Chinese botanical medicine, raised 3.65 million pounds through a placing at 77p a share. Allnewissues said that Ofex-listed stock China Biotech was much cheaper. With warrants over 7 million shares, all of which are in the money, Phynova continues to look overcooked |
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