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MMG Medical Mktg

3.75
0.00 (0.00%)
21 May 2024 - Closed
Delayed by 15 minutes
Share Name Share Symbol Market Type Share ISIN Share Description
Medical Mktg LSE:MMG London Ordinary Share GB0004150685
  Price Change % Change Share Price Bid Price Offer Price High Price Low Price Open Price Shares Traded Last Trade
  0.00 0.00% 3.75 0.00 01:00:00
Industry Sector Turnover Profit EPS - Basic PE Ratio Market Cap
0 0 N/A 0

Interim Results

10/12/2008 8:12am

UK Regulatory


    RNS Number : 8448J
  Medical Marketing Int'l Group PLC
  10 December 2008
   

    MMI announces half year results for the six months ended 30 September 2008

    Wednesday, 10 December 2008 - Medical Marketing International Group plc ("MMI" or the "Company") (AIM:MMG), the life sciences company
focused on the development of drugs for cancer, today announces its half year results for the six months ended 30 September 2008.


    Enquiries:

 Medical Marketing International Group plc
 Phil Cartmell, Non-executive Chairman      Tel: +44 (0) 1223 477 677
 Mark Burton, Chief Technical Officer
 Rob Sprawson, Chief Financial Officer

 FinnCap
 Sam Smith/Charlie Cunningham               Tel: +44 (0)20 7600 1658
                     
 Financial Dynamics
 David Yates/Emma Thompson                  Tel: +44 (0)20 7831 3113


    About MMI
    Medical Marketing International Group plc ("MMI") is a life sciences company that identifies, acquires and develops world-class
compounds and technologies for the treatment of cancer. The Company manages the preclinical and early clinical development of drug
candidates before pursuing licensing partners to manage late-stage development. Please visit www.mmigroup.co.uk for further information.

    Notwithstanding the inclusion on this release by MMI of a website address and/or another electronic address, MMI does not accept any
notices or any other documents or communication via its website or other electronic address. All such notices, documents or communication
shall be in hard copy format only. Accordingly the provisions of section 333 Companies Act 2006 allowing persons to communicate with MMI
electronically shall not apply to MMI.

    Chairman's statement

    MMI is a life sciences business using its platform technologies to develop new products which enhance the treatment of cancer. The half
year position of the Company is both financially and strategically in line with our expectations.

    Vaccines to attack cancer
    A commercial prostate cancer vaccine ("GVX 3322") has been assembled and the DNA sequence verified. GVX 3322 is now undergoing
preclinical equivalence studies with the academic vaccine used in the current clinical trial. The in vivo immunogenicity studies are
on-going and will now complete in the first quarter of 2009. If a positive result is obtained, the Company will continue its preparations
for the commencement of a Phase II trial.

    Planning for the further clinical development of GVX 3322 has continued and discussions with leading clinical oncologists are defining
the key parameters of the next prostate cancer trial. It is evident that the design of this trial will depend critically on the data from
the current trial and, in particular, on the PSA-response rate that is observed. The Company is in discussions with the University of
Southampton and Cancer Research Technology to obtain these data.

    On 29 October 2008 the Company agreed to invest up to £427,500 in its cancer vaccines subsidiary, Genvax, by subscribing for up to 2,850
shares at £150 per share. The investment is staged and is conditional on certain commercial milestones being achieved. However, once fully
subscribed, the Company's stake in Genvax will increase from 58% to 66%.

    Ruthenium chemotherapy
    The ruthenium compound ONCO 4417 has been investigated in a number of studies to enhance our understanding of the mechanism of action by
which it kills cancer cells. These studies show that ONCO 4417 induces DNA damage to levels comparable with that of cisplatin and suggest
that the induced DNA damage may directly or indirectly result in apoptosis (programmed cell death). In addition, as ONCO 4417 does not
appear to share cross-resistance mechanisms with cisplatin, it is likely that damage induced by ONCO 4417 is not resolved in the same way as
that induced by cisplatin and therefore, may provide novel cancer targets for our ruthenium compounds. A summary of this work has been
submitted for presentation at the American Association of Cancer Research Annual Meeting in April 2009.

    ONCO 4417 is being evaluated in a human lung cancer xenograft model including comparison against cisplatin. Previous preclinical results
demonstrated that ONCO 4417 is well tolerated when administered at higher doses and on a more frequent doing schedule than cisplatin.

    We will now focus on investigating the mechanisms responsible for repair of ONCO 4417 induced damage. This knowledge will be used to
target our ruthenium compounds to cancers where the drug will have most effect and to investigate the combination of ONCO 4417 with other
drug agents.

    We have also continued to evaluate the second generation compounds, prepared using a targeted synthesis approach, which have now
demonstrated good in vitro efficacy across our panel of human tumour cells. Finally, the patent portfolio has been strengthened following
the notification of allowance for a third EU patent.

    Disposal of non-core activities
    On 29 September 2008 the Company sold its subsidiary, Bioscience Innovation Centre Limited, for cash consideration of £1. This
transaction facilitated the disposal of excess space whilst retaining not only the Company's current laboratory services revenue stream but
also its fully furnished and equipped laboratories. As a result, recurring facilities costs will be reduced by more than £250,000 each year
and it is intended that these savings will be applied to the further development of the Company's lead oncology programmes.

    The Company continues to explore the possibility of divesting or out-licensing its anti-viral ribozyme technology.  

    Annual General Meeting ("AGM")
    At the Company's AGM held on 17 September 2008 resolutions 1 to 6, being ordinary resolutions, were passed. The results of a poll on
resolutions 7 to 10, being special resolutions, and the AGM were adjourned to 10.30am on 17 December 2008. The Board has since decided to
withdraw these resolutions and therefore the adjourned AGM scheduled for 17 December 2008 will not take place and the AGM is treated as
concluded.

    One of the special resolutions referred to above was to change the Company's name to Oncosense plc to reflect our focus on the oncology
market. Although this resolution has now been withdrawn, we strongly believe that the name Oncosense more accurately reflects our strategy
and business and therefore the Company has started to use Oncosense as a trading name. 

    People
    Our employees are crucial to the success of the Company. We believe that having responsible employees who display sound judgement, are
aware of the consequences of decisions and actions, and who act in an ethical and responsible manner, is key to the future success of the
business. On behalf of the entire Board, we would like to thank our employees for their considerable efforts and support over the last six
months and we look forward to this continuing in the future.

    Financial position
    On 30 July 2008, the Company raised £0.95 million resulting in net funds at 30 September 2008 being £2.18 million (31 March 2008: £2.71
million) which is sufficient to last until June 2009. 

    Outlook
    The Board is committed to the future of MMI and its shareholders and is focused on creating and then realising value from our oncology
pipeline. We are confident that our development plans outlined above are in the best interests of all our stakeholders. We do recognise,
though, that as a development company we rely upon financial support from the shareholder community. With our strategy to build value from
not only the technologies that are being developed but also within the business as a whole, we continue to believe that we have the ability
to return shareholder value in the medium term. 


    Phil Cartmell
    Chairman


    Financial review

    The results for the six months ended 30 September 2008 show an increase in revenue of 14% to £73,053 (2007: £63,834) and an increase in
operating loss of 25% to £2.64 million (2007: £2.11 million). The operating loss includes a charge of £1.59 million for the disposal of a
subsidiary undertaking which if excluded, would reduce the operating loss to £1.05 million, a reduction of 50% on the prior period. The
Company raised £0.95 million in July 2008 resulting in net funds at 30 September 2008 being £2.18 million (31 March 2008: £2.71 million). An
analysis of the key movements is provided below.

    Revenue 
    Revenue continues to comprise fees for services provided to the National Blood Service and for laboratory services, both of which are
expected to continue for the foreseeable future.

    Research and development
    Following the Company's decision to concentrate its resources on the further development of its lead oncology programmes based on its
DNA vaccine and ruthenium technologies, investment in research and development, all of which is expensed as incurred, decreased by 48% to
£469,917 (2007: £899,906).

    Administrative expenses
    Administrative expenses, which primarily comprise staff and establishment costs (excluding those allocated to research and development
expenditure) and professional fees, have been reduced by more than £0.6 million to £653,700 (2007: £1,270,342). This is primarily explained
by the combined effect of:
    *     a significant reduction in Directors' remuneration following the departure of the two founder directors;
    *     savings of approximately £70,000, primarily from advisers' fees;
    *     a recovery of £71,080 under indemnities in previous Directors' consultancy agreements for fees paid gross following a HM Revenue &
Customs inspection in January 2006 (see note 11 of the half-yearly report); and
    *     a decrease in the share-based payments charge of £226,449 to £11,165 (2007: £237,614) following the departure of a number of
employees. 

    Disposal of subsidiary undertaking
    On 29 September 2008 the Company sold its wholly-owned subsidiary, Bioscience Innovation Centre Limited, for cash consideration of £1
resulting in a charge to the consolidated income statement of £1.59 million, £1.43 million of which relates to impairment of the goodwill
originally recognised on the acquisition of Bioscience Innovation Centre Limited (see note 1 of the half-yearly report). 

    The nature of the transaction was such that the only operational impact on the Group was the replacement of a 25 year lease for 25,000
sq ft that expired in 2024 with a new lease for 7,400 sq ft for a minimum of five years. The transaction, which is a significant component
of the Company's cost efficiency programme, facilitated the disposal of excess space so that recurring facilities costs will be reduced by
more than £250,000 each year. It is intended that these savings will be applied to the further development of the Company's lead oncology
programmes.

    Interest income and income tax
    Interest income decreased by 56% to £61,508 (2007: £139,406) primarily due to a lower average net funds balance during the period (2008:
£2.44 million, 2007: £4.83 million). Income tax relates to research and development tax credits for the period.

    Liquidity and capital resources
    The Group's net funds comprise cash and cash equivalents less finance lease liabilities. On 30 July 2008, the Company raised £0.95
million by issuing 5,027,886 ordinary shares at 19 pence each to new and existing shareholders. As a result, net funds at 30 September 2008
were £2.18 million (31 March 2008: £2.71 million). 

      Financial outlook
    The Group intends to continue to fund the development programmes of its oncology platforms whilst seeking potential collaborative
partners. The Directors have prepared cash flow projections which show that current cash resources are sufficient to last until June 2009. 


    Rob Sprawson
Chief Financial Officer

      Consolidated income statement

                                        Six months ended         Six months           Year
                                                                      ended          ended
                                       30 September 2008  30 September 2007  31 March 2008
                                 Note          Unaudited          Unaudited        Audited
                                                      £                  £              £ 

 Revenue                                         73,053             63,834        139,578 
 Research and development                      (469,917)          (899,906)    (1,447,871)
 Administrative expenses                       (653,700)        (1,270,342)    (2,389,099)
 Operating loss before disposal                                            
 of subsidiary undertaking                   (1,050,564)        (2,106,414)    (3,697,392)
 Disposal of subsidiary             1        (1,592,853)                -              -  
 undertaking
 Operating loss                     2        (2,643,417)        (2,106,414)    (3,697,392)
 Interest income                                 61,508            139,406        239,701 
 Finance costs                      3              (333)              (490)          (902)
 Loss before income tax                      (2,582,242)        (1,967,498)    (3,458,593)
 Income tax                         4             7,574             24,264         (3,008)
 Loss for the period                         (2,574,668)        (1,943,234)    (3,461,601)

 Attributable to:
 Equity holders of the Company               (2,571,968)        (1,777,443)    (3,275,561)
 Minority interest                               (2,700)          (165,791)      (186,040)
                                             (2,574,668)        (1,943,234)    (3,461,601)

 Loss per 0.2p ordinary share
 expressed in pence per share
 Basic and diluted                  5            (4.26)p            (3.03)p        (5.59)p


    All income and expenses are derived from continuing operations.
      Consolidated balance sheet

                                                   As at              As at          As at
                                       30 September 2008  30 September 2007  31 March 2008
                                               Unaudited          Unaudited        Audited
                                 Note                 £                  £              £ 
 Assets
 Non-current assets
 Intangible assets                  6           527,660            508,445        527,660 
 Goodwill                           7           296,373          1,716,781      1,722,161 
 Property, plant and equipment                  140,066            261,318        201,439 
                                                964,099          2,486,544      2,451,260 
 Current assets
 Trade and other receivables        9           250,761            336,280        236,241 
 Research and development tax                    54,782            174,967        132,268 
 credit
 Cash and cash equivalents                    2,183,266          3,913,037      2,710,976 
                                              2,488,809          4,424,284      3,079,485 

 Total assets                                 3,452,908          6,910,828      5,530,745 

 Liabilities
 Current liabilities
 Finance lease liabilities                       (2,351)            (2,859)        (3,016)
 Trade and other payables          10          (427,959)          (505,523)      (640,057)
 Provisions for other              11          (143,317)           (69,168)      (315,000)
 liabilities and charges
                                               (573,627)          (577,550)      (958,073)
 Non-current liabilities
 Finance lease liabilities                           -              (2,351)          (804)
 Deferred tax liabilities                      (147,745)          (142,365)      (147,745)
                                               (147,745)     (144,716)           (148,549)

 Total liabilities                             (721,372)          (722,266)    (1,106,622)
 Net assets                                   2,731,536          6,188,562      4,424,123 

 Equity
 Share capital                     12           127,331            117,275        117,275 
 Share premium                               19,616,793         18,755,933     18,755,933 
 Merger reserve                                      -           1,719,733      1,719,733 
 Retained loss                              (17,023,946)       (14,419,471)   (16,182,876)
 Total equity attributable to
 shareholders of the Company                  2,720,178          6,173,470      4,410,065 
 Minority interest in equity                     11,358             15,092         14,058 
 Total equity                                 2,731,536          6,188,562      4,424,123 
    
 Consolidated statement of changes in equity

                                      Share  Share premium        Merger           Retained
                                    capital              £       reserve               loss
                                          £                            £                  £

                                  Unaudited      Unaudited     Unaudited          Unaudited

 At 1 April 2007                   117,275     18,755,933     1,719,733        (12,879,642)

 Loss for the period                    -              -             -          (1,777,443)
 Total recognised income and            -              -             -          (1,777,443)
 expense for the period

 Share-based payments                   -              -             -             237,614 
 Increase in minority interest          -              -             -                  -  
 arising from additional
 investment by parent in
 subsidiary

 At 30 September 2007              117,275     18,755,933     1,719,733        (14,419,471)

                                    Audited        Audited       Audited            Audited

 At 1 April 2007                   117,275     18,755,933     1,719,733        (12,879,642)

 Loss for the period                    -              -             -          (3,275,561)
 Total recognised income and            -              -             -  
 expense for the period                                                         (3,275,561)

 Share-based payments                   -              -             -             (27,673)
 Increase in minority interest          -              -             -                  -  
 arising from additional
 investment by parent in
 subsidiary

 At 31 March 2008                  117,275     18,755,933     1,719,733        (16,182,876)

                                  Unaudited      Unaudited     Unaudited          Unaudited

 At 1 April 2008                   117,275     18,755,933     1,719,733        (16,182,876)

 Loss for the period                    -              -             -          (2,571,968)
 Total recognised income and            -              -             -  
 expense for the period                                                         (2,571,968)

 Issue of ordinary share            10,056        945,242            -                  -  
 capital
 Expenses of issue of ordinary          -       (84,382)             -                   - 
 share capital taken to share
 premium account
 Share-based payments                   -              -             -              11,165 
 Transfer of reserves                   -              -     (1,719,733)         1,719,733 

 At 30 September 2008              127,331     19,616,793            -         (17,023,946)
        
    Table continued* 
                                                Total     Minority         Total
                                                    £     interest        equity
                                                                 £             £

                                            Unaudited    Unaudited     Unaudited

 At 1 April 2007                           7,713,299      100,052     7,813,351 

 Loss for the period                      (1,777,443)    (165,791)   (1,943,234)
 Total recognised income and expense
 for the period                           (1,777,443)    (165,791)   (1,943,234)

 Share-based payments                        237,614           -        237,614 
 Increase in minority interest arising               
 from additional investment by parent             -        80,831        80,831 
 in subsidiary

 At 30 September 2007                      6,173,470       15,092     6,188,562 

                                              Audited      Audited       Audited

 At 1 April 2007                           7,713,299      100,052     7,813,351 

 Loss for the period                      (3,275,561)    (186,040)   (3,461,601)
 Total recognised income and expense                                            
 for the period                           (3,275,561)    (186,040)   (3,461,601)

 Share-based payments                        (27,673)          -        (27,673)
 Increase in minority interest arising                                          
 from additional investment by parent             -       100,046       100,046 
 in subsidiary

 At 31 March 2008                          4,410,065       14,058     4,424,123 

                                            Unaudited    Unaudited     Unaudited

 At 1 April 2008                           4,410,065       14,058     4,424,123 

 Loss for the period                      (2,571,968)      (2,700)   (2,574,668)
 Total recognised income and expense
 for the period                           (2,571,968)      (2,700)   (2,574,668)

 Issue of ordinary share capital             955,298           -        955,298 
 Expenses of issue of ordinary share
 capital taken to share premium account     (84,382)           -       (84,382) 
 Share-based payments                         11,165           -         11,165 
 Transfer of reserves                             -            -             -  

 At 30 September 2008                      2,720,178       11,358     2,731,536 
      Consolidated cash flow statement

                                  Six months ended         Six months           Year
                                                                ended          ended
                                 30 September 2008  30 September 2007  31 March 2008
                                         Unaudited          Unaudited        Audited
                                                £                  £              £ 
 Cash flows from operating
 activities
 Loss for the period                   (2,574,668)        (1,943,234)    (3,461,601)
 Add back:
     Net interest                         (61,175)          (138,916)      (238,799)
     Income tax                            (7,574)           (24,264)         3,008 
 Adjustments for:
     Share-based payments                  11,165            237,614        (27,673)
 charge/(credit)
     Depreciation of property,             60,390             62,696        124,801 
 plant and equipment
     Impairment of goodwill on          1,425,788                 -              -  
 disposal of subsidiary
 undertaking
     Loss on sale of assets                 1,707                 -              -  
 Operating cash flows before                                         
 movement in working capital           (1,144,367)        (1,806,104)    (3,600,264)

 (Increase)/decrease in trade              (9,665)            14,403         62,058 
 and other receivables
 Decrease in trade and other             (212,098)          (189,279)        (2,361)
 payables
 (Decrease)/increase in                                                             
 provisions for other                    (171,683)                -         245,832 
 liabilities and charges
 Cash used in operations               (1,537,813)        (1,980,980)    (3,294,735)

 Interest received                         56,653            137,913        238,208 
 Research and development tax              85,060                 -          15,427 
 credit received
 Net cash used in operating            (1,396,100)        (1,843,067)    (3,041,100)
 activities

 Cash flows from investing
 activities
 Purchase of property, plant                 (725)            (5,121)        (7,347)
 and equipment
 Proceeds from the disposal of                  1                 -              -  
 subsidiary undertaking
 Net cash used in investing                  (724)            (5,121)        (7,347)
 activities

 Cash flows from financing
 activities
 Proceeds from issue of                   955,298                 -              -  
 ordinary share capital
 Expenses paid in connection              (84,382)                -              -  
 with issue of ordinary share
 capital
 Payment of finance lease                  (1,469)            (1,311)        (2,701)
 liabilities
 Interest element of finance                 (333)              (490)          (902)
 lease payments
 Net cash generated/(used) from           869,114             (1,801)        (3,603)
 financing activities

 Decrease in cash and cash               (527,710)        (1,849,989)    (3,052,050)
 equivalents
 Cash and cash equivalents at           2,710,976          5,763,026      5,763,026 
 beginning of period
 Cash and cash equivalents at           2,183,266          3,913,037      2,710,976 
 end of period

    Accounting policies

    The Company is a public limited company incorporated and domiciled in the United Kingdom, with its registered office at The Bioscience
Innovation Centre, Cowley Road, Cambridge, CB4 0DS. The Company's ordinary shares are traded on AIM.

    Basis of preparation

    The half-yearly financial information has been prepared on the basis of the recognition and measurement requirements of IFRS in issue
that either are endorsed by the EU and effective at 31 March 2009 or are expected to be endorsed and effective at 31 March 2009. The
accounting policies that have been adopted are consistent with those set out in the Group's audited accounts for the year ended 31 March
2008. The financial information has been prepared on the historical cost basis and is presented in pounds sterling.    

    The financial information contained in this half-yearly report does not constitute statutory accounts within the meaning of Section 240
of the Companies Act 1985. The results for the six months ended 30 September 2008 and 30 September 2007 have not been audited. The
comparative figures for the financial year ended 31 March 2008 are not the Company's statutory accounts for that financial year. Those
accounts were approved by the Board of Directors on 30 July 2008, have been reported on by the Company's auditors, have been delivered to
the registrar of companies and are available on request from the Company Secretary at The Bioscience Innovation Centre, Cowley Road,
Cambridge, CB4 0DS. The report of the auditors on those accounts was (i) unqualified, (ii) did not contain a statement under section 237(2)
or (3) of the Companies Act 1985, but (iii) did include an emphasis of matter concerning the Company's ability to continue as a going
concern.    

    The half-yearly financial information has been prepared on a going concern basis which the Directors believe to be appropriate for the
following reasons.

    The Group's cash and cash equivalents decreased by £527,710 during the six months ended 30 September 2008 such that, at that date, the
Group's cash resources were £2.18 million. The Directors have prepared cash flow projections which show that current cash resources are
sufficient to last until June 2009.  The Directors have discussed the above and future funding with existing shareholders. There is also the
potential for the Company to secure funding from the divestment of non-core-activities and from possible collaborative opportunities with
pharmaceutical partners.. The Directors recognise that there can be no certainty in relation to these matters, which may cast significant
doubt on the Group's ability to continue as a going concern. The half-yearly financial information does not include any adjustments that
would result if the Group were unable to continue as a going concern.

    Basis of consolidation                                                            
    The half-yearly financial information includes the results of the Company and all of its subsidiary undertakings. The results of
subsidiary undertakings are prepared for the same reporting year as the Company, using consistent accounting policies. Subsidiary
undertakings are consolidated from the date on which control is transferred to the Group and cease to be consolidated from the date on which
control is transferred out of the Group. Control comprises the power to govern the financial and operational policies of a business so as to
obtain benefit from its activities and is achieved through direct or indirect ownership of voting rights. Intra-group transactions, profits
and balances are eliminated in full on consolidation.

    Critical accounting estimates and judgements

    The preparation of financial statements under IFRS requires the Group to make judgements, estimates and assumptions that affect the
application of accounting policies and the reported amounts of assets, liabilities, income and expenses. Estimates and underlying
assumptions are reviewed on an ongoing basis and any resultant revisions are recognised in i) the period in which estimates and underlying
assumptions are revised, and ii) any future periods that are affected. Despite this, actual results may differ from the estimates and
underlying assumptions that have been made.

    The areas of estimation uncertainty and critical judgements in applying accounting policies that have the most significant effect on the
amounts recognised in the half-yearly financial information are i) accounting policies for research and development and intangible assets,
ii) impairment tests for intangible assets and goodwill, iii) provisions for other liabilities and charges, and iv) share based payments.   
                                                        
      Notes to the half-yearly report

 1  Disposal of subsidiary undertaking
    Bioscience Innovation Centre Limited ("BIC"), which until 29 September 2008
    was a wholly owned subsidiary of the Company, leases the Bioscience
    Innovation Centre under a non-cancellable operating lease agreement with
    Turnstone Estates Limited ("TEL") that expires in 2024. Under the terms of
    the lease BIC manages The Bioscience Innovation Centre and its tenants,
    including the Company, pay a service charge for maintenance, servicing and
    security. Whilst BIC was a subsidiary of the Company, the balance held in
    this account was included within other payables and other receivables.
                                                                                
    On 29 September 2008 the Company acquired certain assets of BIC and then
    disposed of BIC (including the operating lease agreement referred to above)
    to TEL for cash consideration of £1. On the same day, the Company i) entered
    into a new lease with BIC, under new ownership, for 7,400 square foot of
    space in The Bioscience Innovation Centre for ten years but with a tenant's
    break at five years and landlord's break at any time from five years, and
    ii) agreed to pay BIC, under new ownership, a fee of £100,000 on completion
    and £100,000 by 30 June 2009.

    As a result of the above, goodwill of £1,425,788 allocated to BIC was deemed
    to be impaired and the loss on sale of assets was £1,707, being
    consideration of £1 less BIC's net assets immediately prior to the
    transaction of £1,708. In addition, the balance held in the service charge
    account was transferred to the Company. Other than the change in the Group's
    lease arrangements, there were no other changes in the operational nature of
    the Group.

   The charge to the income statement on the disposal of BIC is reconciled below:
                                                                             Unaudited
                                                                                    £ 
   Consideration                                                                   (1)
   Sale of net assets                                                           1,708 
   Impairment of goodwill                                                   1,425,788 
   Fee paid to BIC                                                            200,000 
   Balance in BIC's service                                                   (70,164)
   charge account
   Expenses, including stamp                                                   35,522 
   duty, of disposal
                                                                            1,592,853 

    
 2          Operating loss                                                   
         Operating loss is                                                   
              stated after
     charging/(crediting):
                                Six months ended  Six months ended       Year
                                                                        ended
                                    30 September      30 September   31 March
                                            2008              2007       2008
                                       Unaudited         Unaudited    Audited
                                               £                 £          £
           Depreciation of                                                   
       property, plant and
                equipment:
            - owned assets                60,390            62,012    124,117
            - assets under                    -                684        684
            finance leases
      Share-based payments                11,165           237,614   (27,673)
           charge/(credit)
           Operating lease                                                   
                  rentals:
               - equipment                 1,432             1,368      2,865
                - land and               170,000           170,000    340,000
                 buildings


 3  Finance costs
    Finance costs relate to interest payable under finance leases.

      
 4  Income tax
    Taxation relates to research and development tax credits for the period.

 5  Loss per share
    The basic loss per share has been calculated by dividing the loss for the
    six months ended 30 September 2008 by the weighted average number of
    shares of 60,378,093 (2007: 58,637,671) in issue during the period. IAS
    33, "Earnings Per Share", requires presentation of diluted earnings per
    share when a company could be called upon to issue shares that would
    decrease net profit or increase net loss per share. No adjustment is
    required to the basic loss per share as the exercise of options would
    reduce the loss per ordinary share and is therefore not dilutive.

 6  Intangible assets
                                                Genvax     Viratis       Total
                                               Limited    Limited 
                                                    £           £           £ 
    At 1 April 2007                           334,464      93,150     427,614 
    Additions in the six months ended 30       61,573      19,258      80,831 
    September 2007
    At 30 September 2007 (unaudited)          396,037     112,408     508,445 

    Additions in the six months ended 31           -       19,215      19,215 
    March 2008
    At 31 March 2008 (audited) and at 30      396,037     131,623     527,660 
    September 2008 (unaudited)
    Intangible assets, relating to intellectual property, have been recognised as a result of additional investments in subsidiary
undertakings (note 8) since 1 April 2006, the date of the Group's transition to IFRS.


 7  Goodwill
                                    Bioscience    Genvax   Viratis        Total
                            Innovation Centre    Limited  Limited 
                                       Limited
                                            £         £         £            £ 
    At 1 April 2007                 1,425,788   142,664   125,696    1,694,148 
    Additions in the six                   -  
    months ended 30                              17,241     5,392       22,633 
    September 2007
    At 30 September 2007            1,425,788   159,905   131,088    1,716,781 
    (unaudited)

    Additions in the six                   -         -      5,380        5,380 
    months ended 31
    March 2008
    At 31 March 2008                1,425,788   159,905   136,468    1,722,161 
    (audited)

    Impairment in the              (1,425,788)       -         -    (1,425,788)
    six months ended 30
    September 2008
    At 30 September 2008                   -    159,905   136,468      296,373 
    (unaudited)

    Goodwill arising from the acquisition of Bioscience Innovation Centre Limited prior to 1 April 2006 was impaired on the disposal of the
subsidiary undertaking on 29 September 2008 (note 1). Goodwill continues to arise from additional investments in Genvax Limited and Viratis
Limited (note 8).
      
 8  Investments in subsidiary undertakings

   During the 18 months ended 30 September 2008 the Company made the following additional investments in
   subsidiary undertakings:
                                                       Immediately prior to subscription:
                                 Shares owned                Shares           Net assets/     Subscribed shares
                               by the Company              in issue         (liabilities)
                                       Number                Number                     £                Number
   Genvax Limited
   1 June 2007                         6,700                11,700                86,806                   300 
 
   Viratis Limited
   2 April 2007                        4,800                 6,800                96,425                   400 
   23 November 2007                    5,200                 7,200                (7,804)                  500 
 
                                                                                                           900 
 
   In the six months
   ended 30 September
   2008 (unaudited)
   In the six months
   ended 30 September
   2007 (unaudited)
   In the year ended 31
   March 2008 (audited)

    Table continued* 

    
                                                                     Represented by:
                            Amount      Intangible  Goodwill acquired          Other
                          invested          assets                        net assets
                                          acquired                          acquired
                                 £               £                  £              £
          Genvax Limited                                                            
             1 June 2007   150,000          61,573             17,241         71,186
                                                                                    
         Viratis Limited                                                            
            2 April 2007    75,000          19,258              5,392         50,350
        23 November 2007    73,438          19,215              5,380         48,843
                           148,438          38,473             10,772         99,193
                                                                                    
       In the six months       -               -                  -                 
      ended 30 September
        2008 (unaudited)
       In the six months   225,000          80,831             22,633               
      ended 30 September
        2007 (unaudited)
    In the year ended 31   298,438         100,046             28,013               
    March 2008 (audited)

    On the 5 November 2008, the Company invested £67,500 in Genvax Limited by subscribing for 450 new ordinary shares at £150 each.

 9  Trade and other receivables
                                       As at              As at          As at
                           30 September 2008  30 September 2007  31 March 2008
                                   Unaudited          Unaudited        Audited
                                          £                  £              £ 
    Trade receivables                12,833             32,138         24,538 
    Prepayments and                 125,302            207,038        146,313 
    accrued income
    Other receivables                89,766             40,293         54,907 
    VAT recoverable                  22,860             56,811         10,483 
                                    250,761            336,280        236,241 

 10  Trade and other payables
                                       As at              As at          As at
                           30 September 2008  30 September 2007  31 March 2008
                                   Unaudited          Unaudited        Audited
                                          £                  £              £ 
     Trade payables                 123,623             74,353         95,900 
     Other payables                     560             61,162         80,546 
     Other taxation and              32,087             42,965         45,980 
     social security
     costs
     Accruals and                   271,689            327,043        417,631 
     deferred income
                                    427,959            505,523        640,057 

      
 11  Provisions for other liabilities and charges
                                       As at              As at          As at
                           30 September 2008  30 September 2007  31 March 2008

                                   Unaudited          Unaudited        Audited
                                          £                  £              £ 
     At 1 April                     315,000             69,168         69,168 
     Released to income                  -                  -         (39,168)
     statement
     Charged to income                  941                 -         285,000 
     statement
     Utilised                      (172,624)                -              -  
     At 31 March                    143,317             69,168        315,000 
    The provision at 1 April 2008 comprised i) £30,000 remaining balance from an original provision of £207,655 in relation to PAYE and
National Insurance due following a HM Revenue & Customs inspection in January 2006. This has now been settled and the matter has been closed
by HM Revenue & Customs, and ii) a provision for legal fees following the termination of David Best's employment on 12 March 2008 together
with a provision for an Employment Tribunal claim made by David Best, including an amount for legal fees in the defence of the claim,
totalling £285,000, £141,683 of which has been utilised.

 12  Share capital
                                       As at              As at         As at 
                           30 September 2008  30 September 2007  31 March 2008

                                   Unaudited          Unaudited        Audited
                                     Number             Number         Number 
     Ordinary shares with        63,665,557         58,637,671     58,637,671 
     a par value of 0.2
     pence each
    On 30 July 2008, the Company raised £955,298 (before expenses) by issuing 5,027,886 ordinary shares at 19 pence each.
    -ends-

This information is provided by RNS
The company news service from the London Stock Exchange
 
  END 
 
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