Gsk Share Discussion Threads

[gotnorolex] 18/5/2009 10:07

GSK buy Oxford BioTherapeutics (Should have had an RNS by now!)

GlaxoSmithKline (GSK.L) took another step to bolster its early-stage pipeline of cancer drugs on Monday by signing a deal worth up to $370 million with privately held British biotech group Oxford BioTherapeutics.

The strategic alliance covers the discovery and development of new therapeutic antibodies for treating primary, metastatic and recurring forms of cancer, with Glaxo developing drugs against selected targets identified by Oxford BioTherapeutics (OBT).

OBT will also develop one antibody through to clinical proof of concept, at which point Glaxo will have an option to license it.

OBT said it would receive an undisclosed upfront payment and would be eligible for up to a total of $370 million in milestone payments, depending on the success of the new drugs in development. It will also get royalties on any eventual sales.

[bountyhunter] 18/5/2009 07:26

yes suddenly up to around 130 cases in Japan including person to person transmission and they are very concerned

[oneeyedjack01] 18/5/2009 07:01

Could well do. Japan has this and it is taking off there, reports are this may cause WHO to soon raise the level to 6.

[20dynamo] 18/5/2009 06:54

we may see more sector rotation today which may help to support the sp

[sat69] 18/5/2009 06:10

Morning All

Another lower opening today I'm afraid.

[bountyhunter] 16/5/2009 22:57

not about flu at the moment, agreed, but things could change rapidly here;
I sincerely hope they don't (due to any escalation of flu) as I would much rather see a pandemic free world; lets all hope there is no pandemic although don't forget that governements will still continue to build their stockpiles of Relenza (and Tamiflu) and wish to vaccinate their citizens to protect them

[smurfy2001] 16/5/2009 22:32

Thanks, good luck with GSK.

[oneeyedjack01] 16/5/2009 21:38

Good Luck Smurfy but the BGI is priced in. This isnt about Flu. It is about a change in strategy and the fact that money is likely to be flowing into safer stocks.

[bountyhunter] 16/5/2009 21:33

I'm also amazed at how it's still down at this price but I don't think it will stay here or (unfortunately) that flu is yesterday's news, but good luck with your investment in barc.

[smurfy2001] 16/5/2009 19:43

Going to put a sell order on this on Monday, very disappointing performance. As soon as the flu is yesterdays news, this share will dive even further, amazing how it's still at this price..

I will buy more BARC, far more upside to come with the upcoming BGI sale.

[bountyhunter] 16/5/2009 16:36

not even if they paid me !
... but they are the experts of course ;-(
(...not)
maybe the government have given up trying to keep it out - just heard the total in the UK with swine flu is now 87 (with a few thousand in the U.S.)

"The World Health Organisation says the number of confirmed swine flu cases has risen by nearly 1,000 in 24 hours to 8,451."

[montyhedge] 16/5/2009 16:35

Go to Mexico for £150, no thanks. Not even free.

[bountyhunter] 16/5/2009 16:33

the governement have just said it's ok to travel to Mexico again ...can't see any of the cabinet going there unless to sell 2nd/3rd homes! ;-)

[montyhedge] 16/5/2009 16:32

Or Buy the rumour sell the fact.

[montyhedge] 16/5/2009 16:32

Everyone knew, thats why the price dropped, better to travel than arrive, old stockmarket saying.

[bountyhunter] 16/5/2009 16:29

and that of course was just after the first world war - that generation had it much worse than now despite all the serious problems today; my Grandad nearly died; I guess he was one of the lucky ones in the end

[spondon2] 16/5/2009 16:27

Unlikely one eye. They are using the 1918 virus as a precedent which returned 2nd. time round as a more virulent strain but particularly affected those with a strong immune response as opposed to a weak one. Their bodies triggered an inappropriate immune response slightly similar to anaphylatic shock/allergies where a toxin is identified and the immune system mobilised excessively. In 1918 the excessive production of mucous literally caused sufferers to drown in their sputum.

[bountyhunter] 16/5/2009 16:27

yes we are going through very bleak times indeed;
I suspect the more likely outcome is a flu pandemic this winter with the existing casualty rate where there seems to be a good chance of survival (outside Mexico) but the section which you have highlighted is certainly of great concern.

[oneeyedjack01] 16/5/2009 15:36

This is what worries me putting aside being a shareholder of GSK.

"...Experts have warned that although current cases of swine flu have been relatively mild in the developed world, the virus could return in the autumn as a more dangerous disease.

The words "could return as a more dangerous disease"

If so it would attack the weak. I really do find it a coincidence this may pan out after / during the credit crunch with high unemployment and high chronic healthcare spending.

[bountyhunter] 16/5/2009 14:09

from the Telegraph, and well worth a read:



"...Experts have warned that although current cases of swine flu have been relatively mild in the developed world, the virus could return in the autumn as a more dangerous disease.

So far there have been over 7,500 confirmed cases of swine flu worldwide with 70 deaths.

Four more children were confirmed as having swine flu on Friday bringing the total in Britain to 82, with 271 further people under investigation.

The Department of Health will vaccinate high risk groups first, including healthcare workers, people with long-term conditions who normally receive the seasonal flu jab, the elderly and children, who together make up around 45 per cent of the population.

Secretary of State for Health, Alan Johnson said: "The localised cases of swine flu found in the UK have so far been mild, and our strategy of containing the spread with anti-virals appears to have been effective in reducing symptoms and preventing further spread of infection.

"Scientists tell us that as yet we don't know enough about this novel strain, or whether it's likely to mutate, but that this virus has the potential to become a pandemic and we can't predict how serious that would be.

"We have an opportunity to secure vaccine in advance of a pandemic wave.

"These additional arrangements provide the opportunity by December this year to have enough pre-pandemic vaccine to protect at least half of the population from swine flu."

If the WHO does declare a pandemic, these contracts will be superseded by ones already in place under which the UK Government can order up to 132m doses.

The exact timing of the production and deliveries can only be estimated because it is not known yet how well the virus will grow in the laboratory and how much virus antigen will need to be included in each dose.

GlaxoSmithKline has developed a new method of creating vaccine to eek out the precious antigens needed in each dose and still produce full protection against contracting the virus.

The method means that two or three times as much vaccine can be created from the normal amount of antigen, however this will depend on how well the virus grows in the laboratory.

France, Belgium and Finland have also placed orders for H1N1 vaccine with GlaxoSmithKline."

[oneeyedjack01] 16/5/2009 10:20

LORD LUC4N

SINB4D

If you run out of idea's here's one for youre next attempt ....

RICKY4NDBI4NC4

[santa14] 16/5/2009 07:52

pmsl :)


bye sonny boi