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RHHBY Roche Holdings Ltd AG (QX)

40.76
1.20 (3.03%)
26 Jul 2024 - Closed
Delayed by 15 minutes
Name Symbol Market Type
Roche Holdings Ltd AG (QX) USOTC:RHHBY OTCMarkets Depository Receipt
  Price Change % Change Price Bid Price Offer Price High Price Low Price Open Price Traded Last Trade
  1.20 3.03% 40.76 40.59 40.80 40.80 40.12 40.15 2,775,124 22:20:00

Roche Says Phase 3 Studies for Alzheimer's Drug Failed to Meet Primary Endpoints -- Update

14/11/2022 7:40am

Dow Jones News


Roche (QX) (USOTC:RHHBY)
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By Pierre Bertrand

 

Roche Holding AG said Monday that Phase 3 Graduate studies of gantenerumab, for treatment of early Alzheimer's disease, failed to meet its primary endpoints.

The Swiss pharma company said the drug failed to slow patients' clinical decline, adding that the drug's removal of beta-amyloid, a protein that builds up to make plaques in the brains of people with Alzheimer's disease, was lower than expected.

Nearly 2,000 people in 30 countries participated in the studies. Although patients treated with the drug showed a slowing of clinical decline in Graduate I and Graduate II tests by 8% and 6%, respectively, when compared with those given placebos, the results weren't statistically significant, Roche said.

The company said it would keep working on novel diagnostics and treatments for Alzheimer's and that it would present the data at the Clinical Trials on Alzheimer's Disease Conference on Nov. 30.

 

Write to Pierre Bertrand at pierre.bertrand@wsj.com

 

(END) Dow Jones Newswires

November 14, 2022 02:25 ET (07:25 GMT)

Copyright (c) 2022 Dow Jones & Company, Inc.

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