Director Shareholding

RNS Number:8400S
Tepnel Life Sciences PLC
04 December 2003



                    Tepnel Life Sciences plc ("the Company")

                   Additional Placing & Director Shareholding


Manchester, UK. 4th December 2003.  Tepnel Life Sciences PLC (AIM: TED)
announces that subsequent to the Company's announcement on the 31 October 2003
of its acquisition of the Orchid Diagnostics division from Orchid BioSciences
Inc., and associated placing, the Company was approached, through its broker
Seymour Pierce, by an institution that wished to invest in the Company.  In
order to satisfy that demand, the Company today announces that they have placed
with that institution, and certain other private individuals including Alec
Craig, Non-Executive Chairman of the Company, an additional 1,978,261 ordinary
shares of 1p each in the capital of the Company ("Ordinary Shares") at 11.5p per
share.  The gross proceeds of this placing, which will be used for working
capital purposes, are #227,500.

As part of this placing Alec Craig will acquire 173,913 Ordinary Shares bringing
his total holding to 207,163 Ordinary Shares, representing approximately 0.15
per cent. of the enlarged issued share capital of the Company.

Application has been made for the 1,978,261 Ordinary Shares to be admitted to
AIM and it is expected that this should take place on 12 December 2003.


Enquiries:

Tepnel Life Sciences plc                                           0161 946 2200
Ben Matzilevich/Gron Ffoulkes-Davies

Seymour Pierce Limited                                             020 7107 8000
Mark Percy

De Facto Communications                                            020 7496 3300
Richard Anderson/Yvonne Alexander



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