Notifiable Interest

RNS Number:8620R
BioFocus PLC
10 November 2003


BIOFOCUS PLC


10 November 2003


BioFocus plc ("the Company"))


The Company has received notifications ISIS Asset Management Plc, dated 4
November 2003, that as a result of a purchase of 75,000 ordinary shares of 25p
each in the relevant share capital on 3 November 2003 the following fund
management companies in the Friends Provident Group and are interested in the
shares below through client holdings:


ISIS Asset Management Plc is interested in the following shares:


No. of Shares                                                %


2,456,802                                                   15.42


This interest includes the material interest of the clients of ISIS Management
plc referred to below:


Name of Client                              No. of Shares %         Name of Registered Holder


Baronsmead VCT 2 Plc                        201,762       1.27      Chase Nominees Limited
Baronsmead VCT Plc                          201,762       1.27      Chase Nominees Limited
The AIM VCT Trust                           115,038       0.72      Chase Nominees Limited
AIM VCT 2                                   76,692        0.48      Chase Nominees Limited
Active Capital Trust                        641,748       4.03      Chase Nominees Limited



This also includes the material interest of the client of Friends Provident Unit
Managers referred to below:


Name of Client                              No. of Shares %         Name of Registered Holder


ISIS Inv Funds ICVC III AIM Growth Fund     60,000        0.38      Chase Nominees Limited
Stewardship Inv Funds ICVC Stewardship      536,059       3.36      Chase Nominees Limited
Growth



Such interest includes the material interest of the client of ISIS Managed
Pension Funds referred to below:


Name of Client                              No. of Shares %         Name of Registered Holder


ISISMPF Stewardship                         79,682        0.50      Citifriends
FPCP Stwardship                             544,059       3.41      HSBC GS Nominees Limited



In addition, ISIS Asset Management plc, as the holding company of the companies
referred to above is also interested in those shares.  Furthermore, Friends
Provident Life Office, as the holding company of ISIS Asset Management plc is
also interested in the shares referred to above.



END


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