Statement of Changes in Beneficial Ownership (4)

FORM 4

[ ] Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES

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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940

1. Name and Address of Reporting Person * Majors Cary L	2. Issuer Name and Ticker or Trading Symbol STERIS plc [ STE ]	5. Relationship of Reporting Person(s) to Issuer (Check all applicable) _____ Director                    _____ 10% Owner __X__ Officer (give title below)    _____ Other (specify below) Sr VP N America Com Operations
(Last)          (First)          (Middle) C/O 70 SIR JOHN ROGERSON'S QUAY	3. Date of Earliest Transaction (MM/DD/YYYY) 8/10/2020
(Street) DUBLIN, L2 2 (City)        (State)        (Zip)	4. If Amendment, Date Original Filed (MM/DD/YYYY)	6. Individual or Joint/Group Filing (Check Applicable Line) _X _ Form filed by One Reporting Person ___ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security (Instr. 3)	2. Trans. Date	2A. Deemed Execution Date, if any	3. Trans. Code (Instr. 8)		4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Ordinary Shares	8/10/2020		M		3000	A	$69.72	22475	D
Ordinary Shares	8/10/2020		S		3000	D	$156.8435 (1)	19475	D
Ordinary Shares	8/10/2020		S		2355	D	$155.62	17120 (2)	D
Ordinary Shares	8/10/2020		S		218	D	$155.88 (3)	0	I	By 401(k)

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Trans. Date	3A. Deemed Execution Date, if any	4. Trans. Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares
Employee Stock Options (right to buy)	$69.72	8/10/2020		M			3000	(4)	6/1/2026	Ordinary Shares	3000	$0.00	0	D

Explanation of Responses:
(1)	Price reflects a weighted average sale price for multiple transactions ranging from $156.7500 to $156.8950 per share, inclusive. The Reporting Person undertakes to provide, upon request by the SEC Staff, the Issuer or a security holder of the Issuer, full information regarding the number of shares sold at each separate price.
(2)	13,620 of these ordinary shares are restricted. The restrictions on these ordinary shares lapse as follows: 6,500 on June 1, 2021; 2,520 on May 31, 2022; 2,224 on May 31, 2023; and 2,376 on June 3, 2024.
(3)	401(k) Plan STERIS shares liquidated at the price of $155.88 per share on August 10, 2020, constituting the Reporting Person's entire interest in STERIS shares under the 401(k) Plan.
(4)	This option is part of an option to purchase 12,000 STERIS ordinary shares, which are fully vested, which was received in conjunction with the Redomiciliation of the entity organized under the laws of the U.K. and formerly named STERIS plc ("Old STERIS") in exchange for an option to purchase 12,000 Old STERIS ordinary shares for $69.72 per share, subject to the same terms and conditions as the original Old STERIS stock option, except as otherwise required by law.

Reporting Owners
Reporting Owner Name / Address	Relationships
	Director	10% Owner	Officer	Other
Majors Cary L C/O 70 SIR JOHN ROGERSON'S QUAY DUBLIN, L2 2			Sr VP N America Com Operations

Signatures
/s/ Ronald E. Snyder, Authorized Representative under Power of Attorney		8/12/2020
**Signature of Reporting Person		Date