Notice of Iran-related Disclosure Filed Pursuant to Section 13(r)(3) of the Exchange Act (irannotice)

			1 March 2023

Securities and Exchange Commission
100 F Street N.E.
Washington, DC 20549

Re:			Annual Report on Form 20-F for the Year Ended 31 December 2022;
			Notice of disclosure under Section 13(r) of the Securities Exchange Act of 1934

Ladies and Gentlemen:

We give notice to the Commission that we have provided disclosure under Section 13(r) of the Securities Exchange Act of 1934 in our Annual Report on Form 20-F for the year ended 31 December 2022.

Very truly yours,

Banco Santander S.A.

By:			/s/ Marjolein Van Hellemondt
			Marjolein Van Hellemondt
			Chief compliance officer