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Share Name | Share Symbol | Market | Type |
---|---|---|---|
Merck and Co Inc | NYSE:MRK | NYSE | Common Stock |
Price Change | % Change | Share Price | High Price | Low Price | Open Price | Shares Traded | Last Trade | |
---|---|---|---|---|---|---|---|---|
-0.79 | -0.62% | 127.47 | 128.48 | 127.18 | 128.11 | 6,221,929 | 01:00:00 |
By Lisa Beilfuss
Merck & Co. said Friday that its experimental drug combination for treating chronic hepatitis C patients demonstrated a 95% effective rate in a late-stage study.
The study combined grazoprevir and elbasvir in a once-daily tablet and was administered to previously untreated patients, some of whom also had HIV and liver cirrhosis, for 12 weeks.
"Patients with co-morbidities and varying treatment experiences represent important segments of the chronic hepatitis C population in need of additional innovative treatment options," said Dr. Eric Lawitz, vice president at the Texas Liver Institute.
A Merck spokesperson said the company remains on track to submit a New Drug Application with the U.S. Food and Drug Administration in the first half of 2015.
The combined tablet from Merck poses a potential threat to Gilead Sciences Inc.
Also on Friday, Gilead announced results from a midstage study that combined its blockbuster drugs Harvoni and Sovaldi to treat patients with advanced liver disease. Its study showed an 86% effective rate in pretransplant patients, and a 96% cure rate in post-transplant noncirrhotic patients with recurrent hepatitis C.
The two drugs represented more than half of Gilead's 2014 revenue.
Write to Lisa Beilfuss at lisa.beilfuss@wsj.com
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