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Share Name | Share Symbol | Market | Type |
---|---|---|---|
Vigil Neuroscience Inc | NASDAQ:VIGL | NASDAQ | Common Stock |
Price Change | % Change | Share Price | Bid Price | Offer Price | High Price | Low Price | Open Price | Shares Traded | Last Trade | |
---|---|---|---|---|---|---|---|---|---|---|
0.84 | 19.63% | 5.12 | 5.05 | 5.12 | 6.06 | 4.3842 | 4.3842 | 1,794,027 | 16:54:48 |
“2023 marked a year of persistent advancement and landmark achievements for the Company,” said Ivana Magovčević-Liebisch, Ph.D., J.D., President and Chief Executive Officer of Vigil. “Most notably, we were the first company to demonstrate clinical data supporting TREM2 agonism as a potential therapeutic approach in neurodegenerative disease. We accomplished another first when we commenced dosing in our Phase 1 healthy volunteer clinical trial evaluating VG-3927, the only small molecule TREM2 agonist in the clinic for the potential treatment of Alzheimer’s disease.”
Key Clinical Program Highlights for 2023
Iluzanebart (VGL101): A fully human monoclonal antibody candidate targeting human triggering receptor expressed on myeloid cells 2 (TREM2)
VG-3927: A highly active, selective, and brain-penetrant small molecule TREM2 agonist
Key Corporate Highlights for 2023
Corporate Update & 2024 Anticipated Milestones
“We enter 2024 well-positioned to achieve our planned value-driving milestones across our development pipeline,” concluded Dr. Magovčević-Liebisch. “We are confident in our ability to continue executing on our precision medicine strategy while thoughtfully allocating financial resources to best support our current development programs and our commitment to our patient communities.”
J.P. Morgan Healthcare Conference Details
The Company today announced that Dr. Magovčević-Liebisch will present at the 42nd Annual J.P. Morgan Healthcare Conference on Thursday, January 11, 2024, at 7:30 a.m. PT / 10:30 a.m. ET.
To register for the live event, please click here. The live webcast will also be available on the Company’s website on the “Events & Presentations” page in the “Investors” section. An archived webcast will be available for approximately 90 days following the presentation.
About Vigil Neuroscience
Vigil Neuroscience is a clinical-stage biotechnology company focused on developing treatments for both rare and common neurodegenerative diseases by restoring the vigilance of microglia, the sentinel immune cells of the brain. Vigil is utilizing the tools of modern neuroscience drug development across multiple therapeutic modalities in its efforts to develop precision-based therapies to improve the lives of patients and their families. Iluzanebart, Vigil’s lead clinical candidate, is a fully human monoclonal antibody agonist targeting human triggering receptor expressed on myeloid cells 2 (TREM2) in people with adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP), a rare and fatal neurodegenerative disease. Vigil is also developing VG-3927, a novel small molecule TREM2 agonist, to treat common neurodegenerative diseases associated with microglial dysfunction, with an initial focus on Alzheimer’s disease (AD) in genetically defined subpopulations.
Forward-Looking Statements
This press release includes certain disclosures that contain “forward-looking statements” of Vigil Neuroscience (“Vigil” or the “Company”) that are made pursuant to the safe harbor provisions of the federal securities laws, including, without limitation, express or implied statements regarding: the Company’s strategy, business plans and focus; the progress and timing of the clinical development of Vigil’s programs, including the availability of, and expected timing for reporting, data from both the IGNITE Phase 2 clinical trial and the VG-3927 Phase 1 clinical trial; expectations regarding the VG-3927 partial clinical hold; beliefs that the maximum exposure limit for VG-3927 exceeds the predicted efficacious dose; the success and timing of the Company’s interactions with regulatory authorities; beliefs about the ability of the Company to execute on strategy and efficiently allocate financial resources and extend the Company’s cash runway into the second half of 2025. Forward-looking statements are based on Vigil’s current expectations and are subject to inherent uncertainties, risks and assumptions that are difficult to predict. Factors that could cause actual results to differ include, but are not limited to, risks and uncertainties related to uncertainties inherent in the identification and development of product candidates, including the conduct of research activities and the conduct of clinical trials; uncertainties as to the availability and timing of results and data from clinical trials; whether results from preclinical studies and clinical trials will be predictive of the results of later preclinical studies and clinical trials; the timing and content of additional regulatory information from the FDA; the Company’s ability to work with the FDA to successfully remove the partial clinical hold on VG-3927; whether Vigil’s cash resources will be sufficient to fund its foreseeable and unforeseeable operating expenses and capital expenditure requirements; as well as the risks and uncertainties identified in the Company’s filings with the Securities and Exchange Commission (SEC), including Vigil’s Quarterly Report on Form 10-Q for the quarter ended September 30, 2023 and in any subsequent filings Vigil makes with the SEC. Forward-looking statements contained in this announcement are made as of this date, and Vigil undertakes no duty to update such information except as required under applicable law. Readers should not rely upon the information on this page as current or accurate after its publication date.
Internet Posting of Information
Vigil Neuroscience routinely posts information that may be important to investors in the 'Investors' section of its website at https://www.vigilneuro.com. The company encourages investors and potential investors to consult our website regularly for important information about Vigil Neuroscience.
Investor Contact:Leah Gibson Vice President, Investor Relations & Corporate Communications Vigil Neuroscience, Inc.lgibson@vigilneuro.com
Media Contact:Megan McGrath MacDougall Advisorsmmcgrath@macdougall.bio
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