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| Holder | Type | Held (Actual) | % of Outstanding | Market Value | Date Reported |
|---|---|---|---|---|---|
| Healthcap VII, L.P. | Institution | 27,442,389 | 9.75% | US$ 445.94M | 2025-12-31 |
| Odlander, Fredrikson & Co. AB | Institution | 27,442,389 | 9.75% | US$ 445.94M | 2025-12-31 |
| Fourth Swedish National Pension Fund (AP4) | Institution | 23,830,466 | 8.46% | US$ 387.25M | 2025-12-31 |
| HBM Healthcare Investments AG | Institution | 23,433,451 | 8.32% | US$ 380.79M | 2025-12-31 |
| Sanofi | Institution | 16,993,968 | 6.04% | US$ 276.15M | 2025-12-31 |
| Capital Research and Management Company | Institution | 16,777,449 | 5.96% | US$ 272.63M | 2026-05-07 |
| Unionen | Institution | 10,620,000 | 3.77% | US$ 172.58M | 2025-12-31 |
| The Invus Group, LLC | Institution | 8,763,239 | 3.11% | US$ 142.40M | 2025-12-31 |
| C WorldWide Asset Management Fondsmaeglerselskab A/S | Institution | 7,400,000 | 2.63% | US$ 120.25M | 2025-12-31 |
| Avanza Fonder AB | Institution | 6,662,328 | 2.37% | US$ 108.26M | 2025-12-31 |
| Mr. Goran Wessman | Insider | 4,220,680 | 1.50% | US$ 68.59M | 2025-12-31 |
| Tredje AP-fonden | Institution | 3,902,100 | 1.39% | US$ 63.41M | 2025-12-31 |
| AXA Investment Managers S.A. | Institution | 3,611,751 | 1.28% | US$ 58.69M | 2025-12-31 |
| Franklin Resources, Inc. | Institution | 3,600,000 | 1.28% | US$ 58.50M | 2025-12-31 |
| OrbiMed Advisors LLC | Institution | 3,200,000 | 1.14% | US$ 52.00M | 2024-12-31 |
| Handelsbanken Asset Management | Institution | 3,011,744 | 1.07% | US$ 48.94M | 2025-12-31 |
| Jesper Lyckeus | Insider | 3,000,000 | 1.07% | US$ 48.75M | 2025-12-31 |
| Mr. Karl Perlhagen | Insider | 2,747,722 | 0.98% | US$ 44.65M | 2025-12-31 |
| Nordnet Pensionsförsäkring AB | Institution | 2,119,416 | 0.75% | US$ 34.44M | 2025-12-31 |
| Swedbank Robur Fonder AB | Institution | 1,707,163 | 0.61% | US$ 27.74M | 2024-12-31 |
| Mr. Kjell Stenberg | Insider | 1,694,303 | 0.60% | US$ 27.53M | 2025-12-31 |
| Mr. Max Mitteregger | Insider | 1,500,000 | 0.53% | US$ 24.38M | 2025-12-31 |
| Aguja Capital GmbH | Institution | 1,300,000 | 0.46% | US$ 21.13M | 2025-06-30 |
| AXA Towarzystwo Funduszy Inwestycyjnych SA | Institution | 602,462 | 0.21% | US$ 9.79M | 2025-12-31 |
| State Street Global Advisors, Inc. | Institution | 240,900 | 0.09% | US$ 3.91M | 2026-05-31 |
| VeloFunds TFI SA | Institution | 165,180 | 0.06% | US$ 2.68M | 2025-12-31 |
| Ms. Asa Magnusson | Insider | 12,000 | 0.00% | US$ 195.00k | 2025-03-25 |
| American Century Investment Management Inc | Institution | 4,594 | 0.00% | US$ 74.65k | 2026-05-29 |
| Ms. Jessica Shull | Insider | 142 | 0.00% | US$ 2.31k | 2025-03-25 |
| Andra AP-fonden | Institution | 0 | 0.00% | - | 2026-03-25 |
| Dr. Carl-Johan Dalsgaard | Insider | 0 | 0.00% | - | 2026-03-25 |
| Ms. Johanna Grans | Insider | 0 | 0.00% | - | 2026-03-25 |
| Dr. Maarten Kraan | Insider | 0 | 0.00% | - | 2026-03-25 |
| Ms. Nina Carlen | Insider | 0 | 0.00% | - | 2026-03-25 |
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