Statement of Changes in Beneficial Ownership (4)

FORM 4

[ ] Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES

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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940

1. Name and Address of Reporting Person * FRIEDBERG ALBERT	2. Issuer Name and Ticker or Trading Symbol VACCINEX, INC. [ VCNX ]	5. Relationship of Reporting Person(s) to Issuer (Check all applicable) __X__ Director                    __X__ 10% Owner _____ Officer (give title below)    _____ Other (specify below)
(Last)          (First)          (Middle) 181 BAY STREET, SUITE 250	3. Date of Earliest Transaction (MM/DD/YYYY) 5/24/2021
(Street) TORONTO, A6 M5J 2T3 (City)        (State)        (Zip)	4. If Amendment, Date Original Filed (MM/DD/YYYY)	6. Individual or Joint/Group Filing (Check Applicable Line) ___ Form filed by One Reporting Person _ X _ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security (Instr. 3)	2. Trans. Date	2A. Deemed Execution Date, if any	3. Trans. Code (Instr. 8)		4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Common Stock								439555	D
Common Stock								37633	I	By Pan-Atlantic Bank & Trust Ltd. (1)
Common Stock								1710093	I	By Friedberg Global-Macro Hedge Fund Ltd. (2)
Common Stock	5/24/2021		C		1180051	A	(5)	8810652	I	By FCMI Parent Co. (3)
Common Stock	5/24/2021		C		967983	A	(6)	967983	I	By FCMI Financial Corporation (4)

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Trans. Date	3A. Deemed Execution Date, if any	4. Trans. Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares
Option (Right to Acquire)	(5)	5/24/2021		C			21475000	(5)	(5)	Common Stock	1180051	(5)	0	I	By FCMI Parent Co. (3)
Option (Right to Acquire)	(6)	5/24/2021		C			9679833	(6)	(6)	Common Stock	967983	(6)	0	I	By FCMI Financial Corporation (4)

Explanation of Responses:
(1)	Mr. Friedberg is the majority owner of Pan Atlantic Bank & Trust Ltd. and disclaims beneficial ownership of these shares except to the extent of his pecuniary interest therein.
(2)	Mr. Friedberg possesses voting and dispositive power over the reported securities and disclaims beneficial ownership of these shares except to the extent of his pecuniary interest therein.
(3)	Mr. Friedberg is the majority owner, a director and the president of FCMI Parent Co. and disclaims beneficial ownership of these shares except to the extent of his pecuniary interest therein.
(4)	FCMI Financial Corp. is a wholly-owned subsidiary of FCMI Parent Co. Mr. Friedberg disclaims beneficial ownership of these shares except to the extent of his pecuniary interests therein.
(5)	Partnership interests in VX3 (DE) LP, or VX3 were exchanged into shares of Common Stock on a 1-for-0.05495 basis.
(6)	Limited partnership units of Vaccinex Products, LP were exchanged into shares of Common Stock on a 1-for-10 basis.

Reporting Owners
Reporting Owner Name / Address	Relationships
	Director	10% Owner	Officer	Other
FRIEDBERG ALBERT 181 BAY STREET SUITE 250 TORONTO, A6 M5J 2T3	X	X
FCMI Parent Co. 181 BAY STREET SUITE 250 TORONTO, A6 M5J 2T3		X

Signatures
/s/ Scott E. Royer, Attorney-in-Fact for Albert D. Friedberg		6/24/2021
**Signature of Reporting Person		Date
FCMI Parent Co. By: /s/ Dan Scheiner, Vice President		6/24/2021
**Signature of Reporting Person		Date