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Share Name | Share Symbol | Market | Type |
---|---|---|---|
Tempest Therpeutics Inc | NASDAQ:TPST | NASDAQ | Common Stock |
Price Change | % Change | Share Price | Bid Price | Offer Price | High Price | Low Price | Open Price | Shares Traded | Last Trade | |
---|---|---|---|---|---|---|---|---|---|---|
0.0344 | 1.97% | 1.7794 | 1.76 | 1.80 | 1.81 | 1.70 | 1.73 | 317,960 | 23:00:01 |
TREX1 Presentation
Dr. Burdette’s presentation will describe the company’s approach to identify and characterize novel small molecule inhibitors of the 3’-5’ DNA repair exonuclease, TREX1. TREX1 inhibits cGAS/STING signaling and is induced in tumor cells due to genetic instability or therapeutic intervention. Tempest’s program aims to generate an anti-tumor response through selectively activating the STING pathway in advanced metastatic cancers with orally available small molecule inhibitors of TREX1.
Presentation details:
Title: | Small Molecules Targeting the 3’-5’ DNA Repair Exonuclease TREX1 SelectivelyActivate the STING Pathway and Induce Tumor-Specific Immunity |
Date: | Thursday, October 13, 2022 |
Time: | 2:40 p.m. EDT |
TPST-1495 Presentation
In addition, Nicholas DeVito, M.D., a medical oncologist and medical instructor in the laboratory of Dr. Brent Hanks, M.D., Ph.D. at Duke University School of Medicine, will be giving a presentation describing pre-clinical results with TPST-1495, Tempest’s clinical-stage dual inhibitor of the EP2 and EP4 prostaglandin E2 receptors, in mice bearing tumors with designated gene expression profiles.
Presentation details:
Title: | Understanding Tumor-Mediated Immune Evasion to Develop Biomarkers toward Rational Therapeutic Combinations |
Date: | Wednesday, October 12, 2022 |
Time: | 8:40 a.m. EDT |
About Tempest Therapeutics
Tempest Therapeutics is a clinical-stage oncology company advancing small molecules that combine both tumor-targeted and immune-mediated mechanisms with the potential to treat a wide range of tumors. The company’s two novel clinical programs are TPST-1120 and TPST-1495, antagonists of PPARα and EP2/EP4, respectively. Both programs are advancing through clinical trials designed to study the agents as monotherapies and in combination with other approved agents. Tempest is also developing an orally available inhibitor of TREX1, a target that controls activation of the cGAS/STING pathway. Tempest is headquartered in South San Francisco. More information about Tempest can be found on the company’s website at www.tempesttx.com.
Investor Contacts:Sylvia WheelerWheelhouse Life Science Advisorsswheeler@wheelhouselsa.com
Aljanae Reynolds Wheelhouse Life Science Advisorsareynolds@wheelhouselsa.com
1 If approved by the FDA
1 Year Tempest Therpeutics Chart |
1 Month Tempest Therpeutics Chart |
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