Statement of Changes in Beneficial Ownership (4)

FORM 4

[ ] Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES

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3235-0287

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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940

1. Name and Address of Reporting Person * Richmond David S.	2. Issuer Name and Ticker or Trading Symbol ROCKWELL MEDICAL, INC. [ RMTI ]	5. Relationship of Reporting Person(s) to Issuer (Check all applicable) _____ Director                    __X__ 10% Owner _____ Officer (give title below)    __X__ Other (specify below) See Footnotes 1 and 2
(Last)          (First)          (Middle) 3568 WILDWOOD AVENUE	3. Date of Earliest Transaction (MM/DD/YYYY) 12/21/2020
(Street) JACKSON, MI 49202 (City)        (State)        (Zip)	4. If Amendment, Date Original Filed (MM/DD/YYYY)	6. Individual or Joint/Group Filing (Check Applicable Line) ___ Form filed by One Reporting Person _ X _ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security (Instr. 3)	2. Trans. Date	2A. Deemed Execution Date, if any	3. Trans. Code (Instr. 8)		4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Common Stock (1)(2)	12/21/2020		S		42450	D	$1.03	1433309	I	By: The RBI Opportunities Fund II, LLC (4)
Common Stock (1)(2)								3465803	I	By: The RBI Opportunities Fund, LLC (3)
Common Stock (1)(2)								64841	I	By: RBI Private Investment I, LLC (5)
Common Stock (1)(2)								61278	I	By: Richmond Brothers, Inc. (6)(7)
Common Stock (1)(2)								38490	I	By: RBI Private Investment II, LLC (8)
Common Stock (1)(2)								108628	I	By: Richmond Brothers 401(k) Profit Sharing Plan (9)
Common Stock (1)(2)								29787	I	By: Spouse of David S. Richmond (10)
Common Stock (1)(2)								797	I	By: Daughter of David S. Richmond (11)
Common Stock (1)(2)								7	I	By: Son of David S. Richmond (12)
Common Stock (1)(2)								52837	I	By: Matthew J. Curfman
Common Stock (1)(2)								38300	I	By: Spouse of Matthew J. Curfman (13)

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Trans. Date	3A. Deemed Execution Date, if any	4. Trans. Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares

Explanation of Responses:
(1)	This Form 4 is filed jointly by RBI Private Investment I, LLC ("RBI PI"), RBI Private Investment II, LLC ("RBI PII"), The RBI Opportunities Fund, LLC ("RBI Opportunities"), The RBI Opportunities Fund II, LLC ("RBI Opportunities II"), RBI PI Manager, LLC ("RBI Manager"), Richmond Brothers 401(k) Profit Sharing Plan ("RBI Plan"), Richmond Brothers, Inc. ("Richmond Brothers"), David S. Richmond and Matthew J. Curfman (collectively, the "Reporting Persons"). Each of the Reporting Persons may be deemed to be a member of a Section 13(d) group that may be deemed to collectively beneficially own more than 10% of the Issuer's outstanding shares of Common Stock.
(2)	Each of the Reporting Persons disclaims beneficial ownership of the securities reported herein except to the extent of his or its pecuniary interest therein, and this report shall not be deemed to be an admission that any Reporting Person is the beneficial owner of such securities for purposes of Section 16 or for any other purpose.
(3)	Represents securities directly owned by RBI Opportunities. RBI Manager, as the manager of RBI Opportunities, may be deemed to beneficially own the securities owned directly by RBI Opportunities. Mr. Richmond, as the manager of RBI Manager, may be deemed to beneficially own the securities owned directly by RBI Opportunities.
(4)	Represents securities directly owned by RBI Opportunities II. RBI Manager, as the manager of RBI Opportunities II, may be deemed to beneficially own the securities owned directly by RBI Opportunities II. Mr. Richmond, as the manager of RBI Manager, may be deemed to beneficially own the securities owned directly by RBI Opportunities II.
(5)	Represents securities directly owned by RBI PI. RBI Manager, as the manager of RBI PI, may be deemed to beneficially own the securities owned directly by RBI PI. Mr. Richmond, as the manager of RBI Manager, may be deemed to beneficially own the securities owned directly by RBI PI.
(6)	Represents securities directly owned by Richmond Brothers. Mr. Richmond, as the Chairman of Richmond Brothers, may be deemed to beneficially own the securities owned directly by Richmond Brothers. Mr. Curfman as the President of Richmond Brothers, may be deemed to beneficially own the securities owned directly by Richmond Brothers.
(7)	Not reported herein are shares of Common Stock held in certain accounts managed by Richmond Brothers (the "Separately Managed Accounts"). Richmond Brothers is entitled to a management fee from the Separately Managed Accounts based solely on the value of assets under management. Accordingly, neither Richmond Brothers nor any other Reporting Person has a pecuniary interest in any of the shares held in the Separately Managed Accounts for purposes of Section 16.
(8)	Represents securities directly owned by RBI PII. RBI Manager, as the manager of RBI PII, may be deemed to beneficially own the securities owned directly by RBI PII. Mr. Richmond, as the manager of RBI Manager, may be deemed to beneficially own the securities owned directly by RBI PII.
(9)	Represents securities directly owned by RBI Plan. Messrs. Richmond and Curfman, as trustees of RBI Plan, may be deemed to beneficially own the securities owned directly by RBI Plan.
(10)	Represents securities directly owned by Mr. Richmond's spouse. Mr. Richmond may be deemed to beneficially own the securities owned directly by his spouse.
(11)	Represents securities directly owned by Mr. Richmond's daughter. Mr. Richmond may be deemed to beneficially own the securities owned directly by his daughter.
(12)	Represents securities directly owned by Mr. Richmond's son. Mr. Richmond may be deemed to beneficially own the securities owned directly by his son.
(13)	Represents securities directly owned by Mr. Curfman's spouse. Mr. Curfman may be deemed to beneficially own the securities owned directly by his spouse.

Reporting Owners
Reporting Owner Name / Address	Relationships
	Director	10% Owner	Officer	Other
Richmond David S. 3568 WILDWOOD AVENUE JACKSON, MI 49202		X		See Footnotes 1 and 2
RBI Private Investment I, LLC 3568 WILDWOOD AVENUE JACKSON, MI 49202				See Footnotes 1 and 2
RBI Private Investment II, LLC 3568 WILDWOOD AVENUE JACKSON, MI 49202				See Footnotes 1 and 2
RBI OPPORTUNITIES FUND, LLC 3568 WILDWOOD AVENUE JACKSON, MI 49202				See Footnotes 1 and 2
RBI OPPORTUNITIES FUND II, LLC 3568 WILDWOOD AVENUE JACKSON, MI 49202				See Footnotes 1 and 2
RBI PI Manager, LLC 3568 WILDWOOD AVENUE JACKSON, MI 49202		X		See Footnotes 1 and 2
Richmond Brothers 401(k) Profit Sharing Plan 3568 WILDWOOD AVENUE JACKSON, MI 49202				See Footnotes 1 and 2
Richmond Brothers, Inc. 3568 WILDWOOD AVENUE JACKSON, MI 49202				See Footnotes 1, 2 and 3
Curfman Matthew J. 3568 WILDWOOD AVENUE JACKSON, MI 49202				See Footnotes 1 and 2

Signatures
By: /s/ David S. Richmond		12/23/2020
**Signature of Reporting Person		Date
By: RBI Private Investment I, LLC; By: RBI PI Manager, LLC, Manager; By: /s/ David S. Richmond, Manager		12/23/2020
**Signature of Reporting Person		Date
By: RBI Private Investment II, LLC; By: RBI PI Manager, LLC, Manager; By: /s/ David S. Richmond, Manager		12/23/2020
**Signature of Reporting Person		Date
By: The RBI Opportunities Fund, LLC; By: RBI PI Manager, LLC, Manager; By: /s/ David S. Richmond, Manager		12/23/2020
**Signature of Reporting Person		Date
By: The RBI Opportunities Fund II, LLC; By: RBI PI Manager, LLC, Manager; By: /s/ David S. Richmond, Manager		12/23/2020
**Signature of Reporting Person		Date
By: RBI PI Manager, LLC; By: /s/ David S. Richmond, Manager		12/23/2020
**Signature of Reporting Person		Date
By: Richmond Brothers 401(k) Profit Sharing Plan; By: /s/ David S. Richmond, Trustee		12/23/2020
**Signature of Reporting Person		Date
By: Richmond Brothers, Inc.; By: /s/ David S. Richmond, Chairman		12/23/2020
**Signature of Reporting Person		Date
By: /s/ Matthew J. Curfman		12/23/2020
**Signature of Reporting Person		Date