We could not find any results for:
Make sure your spelling is correct or try broadening your search.
Share Name | Share Symbol | Market | Type |
---|---|---|---|
Prothena Corporation PLC | NASDAQ:PRTA | NASDAQ | Common Stock |
Price Change | % Change | Share Price | Bid Price | Offer Price | High Price | Low Price | Open Price | Shares Traded | Last Trade | |
---|---|---|---|---|---|---|---|---|---|---|
0.62 | 2.89% | 22.04 | 14.64 | 50.00 | 22.40 | 21.49 | 21.99 | 530,195 | 01:00:00 |
Prothena management, including Gene Kinney, PhD, President & CEO; Sarah Noonberg, MD, PhD, Chief Medical Officer and Wagner Zago, PhD, Chief Scientific Officer, will discuss progress on Prothena’s clinical and discovery programs. Independent subject matter expert Morie Gertz, MD, Chair Emeritus of the Department of Internal Medicine at Mayo Clinic in Rochester, Minn., will discuss the current AL amyloidosis treatment landscape, unmet medical need and use of NT-proBNP, a cardiac biomarker shown to be predictive of survival in the treatment of patients with AL amyloidosis.
“R&D Day is an opportunity to provide additional insight into our clinical development programs that are advancing toward key milestones, and also to highlight our growing discovery pipeline of innovative approaches for neuroscience and orphan diseases,” stated Gene Kinney, PhD, President and Chief Executive Officer of Prothena.
Clinical Pipeline Highlights
During R&D Day, Prothena will discuss its clinical development pipeline of first-in-class protein immunotherapies including the following program highlights:
NEOD001 is an investigational first-in-class antibody that specifically targets disease-causing misfolded light chain in AL amyloidosis. There are two ongoing late-stage global clinical studies of NEOD001.
PRX002/RG7935 is an investigational first-in-class antibody targeting alpha-synuclein for the potential treatment of Parkinson’s disease and is the subject of a worldwide collaboration with Roche. The Phase 2 PASADENA study in patients with early Parkinson’s disease was initiated in the second quarter of this year and enrollment is ongoing.
PRX004 is an investigational first-in-class antibody that specifically targets disease-causing misfolded transthyretin in ATTR amyloidosis.
Discovery Pipeline Highlights
“Our disciplined approach to advancing new compounds from discovery into clinical development is based on a deep understanding of how to optimally target proteins, assess target engagement and disease progression and develop antibodies that relevantly influence biology,” continued Dr. Kinney. “Beyond the catalysts in our clinical programs, we look forward to advancing our exciting discovery pipeline of novel approaches in the neuroscience and orphan areas including targets such as tau, ALECT2, TDP-43, beta amyloid, and others that are implicated in devastating diseases that lack effective therapies such as Alzheimer’s disease (AD), ALECT2 amyloidosis, frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS).”
During R&D Day Prothena will also discuss a number of its discovery-stage programs in the neuroscience and orphan disease categories including:
Webcast Details
Prothena will host R&D Day today from 12:00 - 2:00 PM ET in New York, NY. For those not able to attend, a live webcast that will include audio and slides of the presentation can be accessed through the Investors section of the Company's website at www.prothena.com. Following the live presentations, a replay of the webcast will be available on the Company's website for at least 90 days.
About Prothena
Prothena Corporation plc is a global, late-stage clinical biotechnology company establishing fully integrated research, development and commercial capabilities and focused on advancing new therapies in the neuroscience and orphan arenas. Fueled by its deep scientific understanding built over decades of research in protein misfolding, Prothena seeks to fundamentally change the course of grave or currently untreatable diseases associated with this biology. Prothena’s pipeline of antibody therapeutic candidates targets a number of indications including AL amyloidosis (NEOD001), Parkinson’s disease and other related synucleinopathies (PRX002/RG7935) and ATTR amyloidosis (PRX004). The Company continues discovery of additional novel therapeutic candidates where its deep scientific understanding of disease pathology can be leveraged. For more information, please visit the Company's website at www.prothena.com.
Forward-looking Statements
This press release contains forward-looking statements. These statements relate to, among other things, the predictive value of the cardiac biomarker NT-proBNP; the timing of announcing topline results from the Phase 2b PRONTO study of NEOD001; the timing of initiating a Phase 1 study of PRX004; our expectations on a new assay for detecting circulating misfolded-hATTR in plasma; our ability to advance a growing pipeline of novel first-in-class therapies in neuroscience and orphan diseases; and the potential targeting of novel epitopes we have identified on misfolded forms of tau protein and on misfolded forms of LECT2 protein. These statements are based on estimates, projections and assumptions that may prove not to be accurate, and actual results could differ materially from those anticipated due to known and unknown risks, uncertainties and other factors, including but not limited to the risks, uncertainties and other factors described in the “Risk Factors” sections of our Annual Report on Form 10-K filed with the Securities and Exchange Commission (SEC) on February 27, 2017 and our subsequent Quarterly Reports on Form 10-Q filed with the SEC. Prothena undertakes no obligation to update publicly any forward-looking statements contained in this press release as a result of new information, future events or changes in Prothena's expectations.
Media & Investor Contact:
Ellen Rose, Head of Communications650-922-2405, ellen.rose@prothena.com
1 Year Prothena Chart |
1 Month Prothena Chart |
It looks like you are not logged in. Click the button below to log in and keep track of your recent history.
Support: +44 (0) 203 8794 460 | support@advfn.com
By accessing the services available at ADVFN you are agreeing to be bound by ADVFN's Terms & Conditions