Pharvaris Announces Data Highlighting Deucrictibant for the Treatment of HAE to be Presented at the 2024 HAEi Global Leadership Workshop

Pharvaris (Nasdaq: PHVS), a late-stage biopharmaceutical company developing novel, oral bradykinin B2 receptor antagonists to prevent and treat hereditary angioedema (HAE) attacks, today announced the acceptance of six abstracts, two for oral presentation and four for poster presentation, at the 2024 Global Angioedema Forum – HAEi Global Leadership Workshop, taking place in Copenhagen, Denmark, from Oct. 4-5, 2024. Details are as follows:

• Title: Long-Term Safety and Efficacy of Oral Deucrictibant, a Bradykinin B2 Receptor Antagonist, for Prophylaxis in Hereditary Angioedema: Results of the CHAPTER-1 Open-Label Extension StudyPresenter: Marc A. Reidel, M.D., M.S.Format: Oral and PosterDate, time: Oral: Saturday, Oct. 5, Session 5, 9:59 CEST (3:59 a.m. EDT) | Poster: Friday, Oct. 4, 18:00-18:30 CEST (12:00-12:30 p.m. EDT), Poster Walk 1
• Title: Long-Term Efficacy and Safety of Oral Deucrictibant, a Bradykinin B2 Receptor Antagonist, in Treatment of Hereditary Angioedema Attacks: Results of the RAPIDe-2 Extension StudyPresenter: Anna Valerieva, M.D., Ph.D.Format: Oral and PosterDate, time: Oral: Saturday, Oct. 5, Session 5, 10:08 CEST (4:08 a.m. EDT) | Friday, Oct. 4, 18:30-19:00 CEST (12:30-1:00 p.m. EDT), Poster Walk 4
• Title: Efficacy and Safety of Oral Deucrictibant, a Bradykinin B2 Receptor Antagonist, in Prophylaxis of Hereditary Angioedema Attacks: Results of CHAPTER-1 Phase 2 TrialPresenter: Emel Aygören-Pursun, M.D.Format: Poster Date, time: Friday, Oct. 4, 18:00-18:30 CEST (12:00-12:30 p.m. EDT), Poster Walk 3
• Title: Prophylactic Treatment With Oral Deucrictibant Improves Health-Related Quality of Life of Patients with Hereditary AngioedemaPresenter: Andrea Zanichelli, M.D., Ph.D.Format: PosterDate, time: Friday, Oct. 4, 18:30-19:00 CEST (12:30-1:00 p.m. EDT), Poster Walk 2
• Title: Propensity Score-Matched Comparison of Outcomes for Deucrictibant vs. Standard of Care in People Living with Hereditary AngioedemaPresenter: Danny M. Cohn, M.D., Ph.D.Format: PosterDate, time: Friday, Oct. 4, 18:30-19:00 CEST (12:30-1:00 p.m. EDT), Poster Walk 2
• Title: Design of RAPIDe-3 Phase 3 Trial: Efficacy and Safety of the Oral Bradykinin B2 Receptor Antagonist Deucrictibant Immediate-Release Capsule in Treatment of Hereditary Angioedema AttacksPresenter: Phillip H. Li, MBBS, FRCPFormat: PosterDate, time: Friday, Oct. 4, 18:00-19:00 CEST (12:00-1:00 p.m. EDT), Poster Walk 1

The presentation slides and posters will be available on the Investors section of the Pharvaris website at: https://ir.pharvaris.com/news-events/events-presentations.

In memory of Prof. Marcus Maurer, Professor of Dermatology and Allergy, Executive Director of the Institute of Allergology at the Charité – Universitätsmedizin Berlin, and Co-Director of Allergology and Immunology at the Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Pharvaris will make a donation to the Marcus Maurer Fellowship Program through GA2LEN, the Global Allergy and Asthma Excellence Network.

About PharvarisPharvaris is a late-stage biopharmaceutical company developing novel, oral bradykinin B2 receptor antagonists to prevent and treat HAE attacks. By directly pursuing this clinically proven therapeutic target with novel small molecules, the Pharvaris team aspires to offer people with all types of bradykinin-mediated angioedema effective, well-tolerated, and easy-to-administer alternatives to treat attacks, both prophylactically and on-demand. With positive data in both Phase 2 prophylaxis and on-demand studies in HAE, Pharvaris is encouraged to further develop deucrictibant. Pharvaris is currently enrolling a pivotal Phase 3 study for the on-demand treatment of HAE attacks and plans to initiate a pivotal Phase 3 study of deucrictibant for the prevention of HAE attacks in the coming months. For more information, visit https://pharvaris.com/.

Contact
Maggie Beller
Executive Director, Head of Corporate and Investor Communications
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