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Share Name | Share Symbol | Market | Type |
---|---|---|---|
Pacific Biosciences of California Inc | NASDAQ:PACB | NASDAQ | Common Stock |
Price Change | % Change | Share Price | Bid Price | Offer Price | High Price | Low Price | Open Price | Shares Traded | Last Trade | |
---|---|---|---|---|---|---|---|---|---|---|
0.08 | 5.80% | 1.46 | 1.44 | 1.48 | 1.5395 | 1.36 | 1.4499 | 7,986,911 | 00:58:14 |
The company will also introduce a new Sequel System chemistry release (1.2.1) that enables loading of sequencing libraries with average insert size of 20-30 kb onto Sequel SMRT Cells with a ~50-fold reduction of DNA input requirement compared to previous Sequel chemistry. Internal results using the new Sequel System chemistry, which have been replicated at several beta sites, have shown mapped read-length N50s of >16 kb and output of >5 Gb per Sequel SMRT Cell. Additional details will be discussed during the company’s ASHG workshop (more details on the event below), and commercial availability is expected starting October 25, 2016.
Highlights from the scientific presentations featuring PacBio® sequencing include:
PacBio Workshop at ASHG and Streaming OnlinePacBio will also be hosting a workshop on Thursday, 10/20 at 1:00 p.m. Pacific Time entitled “Discovering and Targeting Causative Variation Underlying Human Genetic Disease Using SMRT Sequencing.” The workshop will focus on genetic discovery advances using the new Sequel System, with a keynote presentation by Euan Ashley from Stanford University School of Medicine. Dr. Ashley’s talk will feature the use of 10-fold long-read WGS of an individual to demonstrate the improved structural variant discovery power of SMRT Sequencing for precision medicine over short-read NGS methods. Dan Burns from Duke University will also be speaking at the workshop and highlighting the improved structural variant resolving power of PacBio long-read sequencing in targeted sequencing studies. Melissa Laird Smith’s workshop talk will feature Sequel data generated at the Icahn School of Medicine at Mount Sinai, where SMRT Sequencing is used as a translational research tool to investigate germline, somatic and infectious disease.
The workshop will be hosted by PacBio Chief Scientific Officer, Jonas Korlach, who will be sharing updates on PacBio’s technology roadmap, including the new chemistry release and loading improvements mentioned above. Dr. Korlach will also be presenting data from 10-fold sequencing of the well-studied NA12878 human genome using the Sequel System, and describing the >15,000 structural variants discovered in this genome using an improved structural variant calling and visualization workflow. This dataset will be available to view using a new version of the Integrative Genomics Viewer, with improved support for PacBio SMRT Sequencing data, at the PacBio booth on the exhibit hall floor (#718). Attendees interested in reserving a seat at the workshop, or scientists not attending the meeting who wish to watch the live stream online, can register here.
“Last year at this time we launched our new Sequel System, and this year scientists will hear some of the first presentations about data and results obtained using this improved and enhanced SMRT Sequencing platform,” said Dr. Korlach. “We are excited to join our customers and colleagues at the industry’s most important annual human genetics meeting, though we are deeply saddened that one of the most important contributors to the field will not be joining us. Dr. Allen Roses was scheduled to speak at our workshop, and due to his unexpected passing we will take time during our event to pay tribute to his legacy.”
About Pacific Biosciences
Pacific Biosciences of California, Inc. (NASDAQ:PACB) offers sequencing systems to help scientists resolve genetically complex problems. Based on its novel Single Molecule, Real-Time (SMRT®) technology, Pacific Biosciences’ products enable: de novo genome assembly to finish genomes in order to more fully identify, annotate and decipher genomic structures; full-length transcript analysis to improve annotations in reference genomes, characterize alternatively spliced isoforms in important gene families, and find novel genes; targeted sequencing to more comprehensively characterize genetic variations; and real-time kinetic information for epigenome characterization. Pacific Biosciences’ technology provides high accuracy, ultra-long reads, uniform coverage, and is the only DNA sequencing technology that provides the ability to simultaneously detect epigenetic changes. PacBio® sequencing systems, including consumables and software, provide a simple, fast, end-to-end workflow for SMRT Sequencing. More information is available at www.pacb.com.
Forward-Looking Statements
All statements in this press release that are not historical are forward-looking statements, including, among other things, statements relating to future uses, quality or performance of, or benefits of using, products or technologies, updates or improvements of the company’s products, and other future events. You should not place undue reliance on forward-looking statements because they involve known and unknown risks, uncertainties, changes in circumstances and other factors that are, in some cases, beyond Pacific Biosciences’ control and could cause actual results to differ materially from the information expressed or implied by forward-looking statements made in this press release. Factors that could materially affect actual results can be found in Pacific Biosciences’ most recent filings with the Securities and Exchange Commission, including Pacific Biosciences’ most recent reports on Forms 8-K, 10-K and 10-Q, and include those listed under the caption “Risk Factors.”
Pacific Biosciences undertakes no obligation to revise or update information in this press release to reflect events or circumstances in the future, even if new information becomes available.
Contacts Media: Nicole Litchfield 415.793.6468 nicole@bioscribe.com Investors: Trevin Rard 650.521.8450 ir@pacificbiosciences.com
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