Initial Statement of Beneficial Ownership (3)

FORM 3	UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES	OMB APPROVAL OMB Number: 3235-0104 Estimated average burden hours per response... 0.5
	Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940

1. Name and Address of Reporting Person * Peraza Lisa	2. Date of Event Requiring Statement (MM/DD/YYYY) 10/13/2020	3. Issuer Name and Ticker or Trading Symbol HERON THERAPEUTICS, INC. /DE/ [HRTX]
(Last)        (First)        (Middle) 4242 CAMPUS POINT COURT, SUITE 200	4. Relationship of Reporting Person(s) to Issuer (Check all applicable) _____ Director                          _____ 10% Owner ___X___ Officer (give title below)        _____ Other (specify below) VP, Chief Accounting Officer /
(Street) SAN DIEGO, CA 92121       (City)              (State)              (Zip)	5. If Amendment, Date Original Filed(MM/DD/YYYY)	6. Individual or Joint/Group Filing(Check Applicable Line) _X_ Form filed by One Reporting Person ___ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security (Instr. 4)	2. Amount of Securities Beneficially Owned (Instr. 4)	3. Ownership Form: Direct (D) or Indirect (I) (Instr. 5)	4. Nature of Indirect Beneficial Ownership (Instr. 5)
Common Stock	11259	D

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security (Instr. 4)	2. Date Exercisable and Expiration Date (MM/DD/YYYY)		3. Title and Amount of Securities Underlying Derivative Security (Instr. 4)		4. Conversion or Exercise Price of Derivative Security	5. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 5)	6. Nature of Indirect Beneficial Ownership (Instr. 5)
	Date Exercisable	Expiration Date	Title	Amount or Number of Shares
Employee Stock Option (Right to Buy)	(1)	3/31/2024	Common Stock	35000	$13.91	D
Employee Stock Option (Right to Buy)	(1)	12/12/2024	Common Stock	17417	$9.05	D
Employee Stock Option (Right to Buy)	(1)	12/22/2025	Common Stock	20000	$29.41	D
Employee Stock Option (Right to Buy)	(1)	10/7/2026	Common Stock	20000	$16.83	D
Employee Stock Option (Right to Buy)	(2)	12/21/2026	Common Stock	27500	$13.00	D
Employee Stock Option (Right to Buy)	(2)	2/13/2027	Common Stock	25000	$13.85	D
Employee Stock Option (Right to Buy)	(2)	12/18/2027	Common Stock	27500	$17.00	D
Employee Stock Option (Right to Buy)	(2)	12/15/2028	Common Stock	20160	$24.97	D
Employee Stock Option (Right to Buy)	(2)	12/19/2029	Common Stock	26400	$25.02	D

Explanation of Responses:
(1)	The stock option is fully vested and exercisable.
(2)	The stock option vests and becomes exercisable in 48 equal monthly installments beginning one month after the date of grant.

Reporting Owners
Reporting Owner Name / Address	Relationships
	Director	10% Owner	Officer	Other
Peraza Lisa 4242 CAMPUS POINT COURT SUITE 200 SAN DIEGO, CA 92121			VP, Chief Accounting Officer

Signatures
/s/ Lisa Peraza		10/15/2020
**Signature of Reporting Person		Date