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Share Name | Share Symbol | Market | Type |
---|---|---|---|
Corcept Therapeutics Inc | NASDAQ:CORT | NASDAQ | Common Stock |
Price Change | % Change | Share Price | Bid Price | Offer Price | High Price | Low Price | Open Price | Shares Traded | Last Trade | |
---|---|---|---|---|---|---|---|---|---|---|
-0.05 | -0.21% | 23.32 | 22.52 | 23.99 | 23.939 | 23.285 | 23.47 | 1,788,923 | 00:13:37 |
CHICAGO, IL--(Marketwired - Jun 20, 2014) - In the news release, "New Research on Corcept's Korlym(R) for Patients With Cushing's Syndrome to Be Presented at ICE/ENDO 2014," issued Thursday, June 19, 2014 by Corcept Therapeutics (NASDAQ: CORT), we are advised by the company that the session schedule has now been updated to reflect accurate presentation times with poster numbers added. Complete corrected text follows.
New Research on Corcept's Korlym® for Patients With Cushing's Syndrome to Be Presented at ICE/ENDO 2014
New Data Includes Results of a Long-Term Extension Phase of Corcept's Multicenter, Open-Label SEISMIC Study
CHICAGO, IL -- Jun 19, 2014 -- Corcept Therapeutics Incorporated (NASDAQ: CORT), a pharmaceutical company engaged in the discovery, development and commercialization of drugs for the treatment of severe metabolic, psychiatric and oncologic disorders, today announced that new clinical research on Korlym® (mifepristone) will be presented at the joint meeting of the International Society of Endocrinology and the Endocrine Society (ICE/ENDO 2014).
The research, including results of a long-term extension phase of Corcept's multicenter, open-label SEISMIC study of Korlym, will be presented at the conference, taking place at the McCormick Place West Convention Center in Chicago from June 21-24. Korlym is a once-daily oral treatment for patients with Cushing's syndrome who have glucose intolerance and have failed or cannot have surgery.
"Cushing's syndrome, which is caused by excessive cortisol activity, is a serious condition that has a debilitating impact on all aspects of patients' lives. The disease often significantly affects patients' metabolism, leading to extreme weight gain with abnormal fat deposits, impaired glycemic control including type 2 diabetes, muscle weakness and, commonly, psychiatric symptoms," said Joseph K. Belanoff, M.D., Corcept's Chief Executive Officer. "Because Cushing's syndrome may be a chronic disease, it is important to monitor patients taking Korlym over time. The long-term extension study of SEISMIC includes data from patients who had been receiving treatment for as long as 3.5 years."
Cushing's syndrome is the result of excessive cortisol activity throughout the body. Cortisol is a hormone made in the adrenal glands that performs vital tasks such as regulating the metabolism of proteins, carbohydrates and fats. Cushing's syndrome afflicts 20,000 people in the United States, with approximately 3,000 to 4,000 new cases each year. Approximately half of these patients are cured by surgery.
The following abstracts highlight new research on mifepristone:
Date | Session Time | Poster Number | Title | Authors | |
Saturday, June 21, 2014 | 11:30am-1:00pm | OR02-2 | Late-Night Salivary Cortisol for the Diagnosis of Recurrent Cushing's Disease: Evidence of Clinical Benefit from Early Detection | Ty Brian Carroll, MD; Bradley R Javorsky, MD; James W Findling, MD | |
1:00-3:00pm | SAT-0671 | Clinical Management in a Female with Persistent Cushing's Disease Treated with Mifepristone for Four Years | Elizabeth E King, MD; Simone M Howell, RN, CCRA | ||
Sunday, June 22, 2014 | 1:00-3:00pm | SUN-0750 | Effect of Mifepristone on Cushing's syndrome Secondary to Bilateral Adrenal Adenomas: A Case Presentation | Vijay Babu Balakrishnan; Pankaj Sharda, MBBS, MD; Elias Said Siraj, MD | |
Monday, June 23, 2014 | 1:00-3:00pm | MON-0439 | Improved Activities of Daily Living, Normal Mood and Quality of Life: 4 Years of Treatment Data in a Premenopausal Woman with Cushing's Disease | Daphne T Adelman, BSN, MBA; Simone M Howell, RN, CCRA | |
MON-0592 | A Case Report of a 37 y/o Woman Diagnosed with Cushing's Disease Presenting As Pituitary Apoplexy after Multiple Treatment Failures Effectively Responds to Mifepristone | Howard A Brand, MD; Kimberly Calcagno, MA; Michele Lamerson, RN, MS, CPNP | |||
MON-0595 | Discontinuation of Insulin, Oral Antidiabetic and Antihypertensive Medications in a Patient with Cushing's Disease Following Mifepristone (MIFE) Therapy | Kevin C.J. Yuen, MD, FRCP (UK); Harold I Magazine, PhD | |||
MON-0598 | Mifepristone for Refractory Cushing's Syndrome in a Patient with CKD Hyperkalemia Undergoing Surgical Exodontia and Weight Loss: Recommendations for Clinical/Biochemical Monitoring and Perioperative Dosing | Audrey Elisabeth Arzamendi, MD; Alison Marie Semrad, DO | |||
MON-0663 | Persistent Weight Loss in Patients Treated with Mifepristone (MIFE) for Cushing's Syndrome: Results from the Seismic & Long Term Extension Studies | Henry G. Fein, MD; T. Brooks Vaughan III, MD; Coleman Gross; Dat Nguyen | |||
About Corcept Therapeutics Incorporated Corcept is a pharmaceutical company engaged in the discovery, development and commercialization of drugs that regulate the effects of the stress hormone cortisol on the body. The FDA has approved the company's first drug, Korlym® (mifepristone) 300 mg Tablets, a glucocorticoid receptor antagonist, as a once-daily oral treatment for hyperglycemia secondary to endogenous Cushing's syndrome in adult patients with glucose intolerance or diabetes mellitus type 2 who have failed surgery or are not candidates for surgery. Corcept is exploring mifepristone (the active ingredient in Korlym) as a treatment for triple-negative breast cancer with a multi-center, Phase I clinical study currently underway in patients with metastatic or locally advanced unresectable breast cancer. It is also supporting investigator-led clinical studies of mifepristone in the treatment of ovarian cancer and castration-resistant prostate cancer. The company has a portfolio of selective glucocorticoid-receptor (GR) antagonists that block the effects of cortisol but not progesterone. It owns or has licensed extensive intellectual property covering the use of GR antagonists, including mifepristone, in the treatment of a wide variety of metabolic and psychiatric disorders and triple-negative breast cancer. It also holds composition of matter patents for its selective GR antagonists.
Investor Contact Charles Robb Corcept Therapeutics Incorporated Chief Financial Officer Email Contact 650-688-8783 Media Contact Brian Baxter for Corcept Lazar Partners Ltd. Email Contact 646-871-8491
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