Bruker’s New CryoProbe™ Prodigy TCI 600 Delivers a 2.5x Proton Sensitivity Boost, Providing a more than 6-fold Throughput...

At the Experimental Nuclear Magnetic Resonance Conference (ENC) 2012, Bruker announces the new CryoProbe Prodigy TCI, the latest member of the Prodigy product line that delivers tremendous boosts in sensitivity at affordable prices. Prodigy TCI uses nitrogen-cooled RF coils and preamplifiers to deliver a proton sensitivity enhancement of a factor of 2.5, and a carbon sensitivity enhancement of a factor of 2 over room temperature inverse triple-resonance (RT TXI) probes.

CryoProbe Prodigy TCI 600 (Photo: Business Wire)

Available at 600 MHz, the innovative design of the Prodigy TCI not only delivers an incredible performance boost, but does so with minimum operating and maintenance costs, and with long service intervals of over 2 years. The Prodigy TCI requires no additional infrastructure and is therefore easy to site within a small footprint. A 600 MHz Bruker AVANCE™ III HD spectrometer equipped with the Prodigy TCI now surpasses 950 MHz NMR room-temperature probes on conventional spectrometers in proton sensitivity. The larger than ‘300 MHz-equivalent’ sensitivity boost makes Prodigy TCI easy-to-use and cost-effective for routine and research NMR applications.

Proton-detected NMR experiments in biomolecular and pharmaceutical research will benefit from the 2.5x increase in signal-to-noise, enabling time-consuming NMR experiments to be performed more than 6 times faster. The design of the Prodigy TCI with its cooled 13C preamplifier enhances versatility compared to conventional TXI probes, and its RF power handling challenges that of RT probes. The CryoProbe Prodigy TCI will enable structural biology research labs, as well as small molecule NMR labs in pharmaceutical and chemical industries, to drastically increase their sample throughput. Combined with an optional automatic tuning and matching accessory (ATMA), the Prodigy TCI is now the probe of choice in terms of cost/performance ratio for many industrial and academic labs.

The Prodigy TCI is yet another extension of Bruker’s unique, game-changing CryoProbe technology. As the pioneer and leader in the development of cryogenically cooled probes for high-resolution NMR and preclinical MRI, Bruker remains unmatched with over 1,100 CryoProbes installed worldwide.

“The Prodigy TCI expands the successful CryoProbe Prodigy product line introduced in 2011,” commented Dr. Werner Maas, President of Bruker BioSpin. “More than a decade ago Bruker’s first CryoProbes created a paradigm shift in biological NMR. Now the new, cost-effective CryoProbe Prodigy product line is enabling routine and analytical NMR customers to benefit from an incredible ‘300 MHz-equivalent’ boost in sensitivity.”

About Bruker Corporation

Bruker Corporation (NASDAQ: BRKR) is a leading provider of high performance scientific instruments and solutions for molecular and materials research, as well as industrial and applied analysis. For more information: www.bruker.com.

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