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Share Name | Share Symbol | Market | Type |
---|---|---|---|
Benitec Biopharma Limited | NASDAQ:BNTC | NASDAQ | Common Stock |
Price Change | % Change | Share Price | Bid Price | Offer Price | High Price | Low Price | Open Price | Shares Traded | Last Trade | |
---|---|---|---|---|---|---|---|---|---|---|
-0.55 | -6.51% | 7.90 | 6.86 | 9.00 | 8.82 | 7.55 | 8.64 | 38,143 | 23:00:02 |
☒ |
QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(D) OF THE SECURITIES EXCHANGE ACT OF 1934
|
☐ |
TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(D) OF THE SECURITIES EXCHANGE ACT OF 1934
|
Delaware
|
84-462-0206
|
|
(State or other jurisdiction of
incorporation or organization)
|
(IRS Employer
Identification No.)
|
Title of each class
|
Trading
Symbol(s)
|
Name of each exchange
on which registered
|
||
Common Stock, par value $0.0001
|
BNTC
|
The Nasdaq Stock Market LLC
|
Large accelerated filer | ☐ | Accelerated filer | ☐ | |||
Non-accelerated filer | ☒ | Smaller reporting company | ☒ | |||
Emerging growth company | ☐ |
• |
the success of our plans to develop and potentially commercialize our product candidates;
|
• |
the timing of the initiation and completion of preclinical studies and clinical trials;
|
• |
the timing and sufficiency of patient enrollment and dosing in any future clinical trials;
|
• |
the timing of the availability of data from clinical trials;
|
• |
the timing and outcome of regulatory filings and approvals;
|
• |
unanticipated delays;
|
• |
sales, marketing, manufacturing and distribution requirements;
|
• |
market competition and the acceptance of our products in the marketplace;
|
• |
regulatory developments in the United States of America;
|
• |
the development of novel AAV vectors;
|
• |
the plans of licensees of our technology;
|
• |
the clinical utility and potential attributes and benefits of ddRNAi and our product candidates, including the potential duration of treatment effects and the potential for a “one shot” cure;
|
• |
our dependence on our relationships with collaborators and other third parties;
|
• |
expenses, ongoing losses, future revenue, capital needs and needs for additional financing, and our ability to access additional financing given market conditions and other factors, including our capital structure;
|
• |
the length of time over which we expect our cash and cash equivalents to be sufficient to execute on our business plan;
|
• |
our intellectual property position and the duration of our patent portfolio;
|
• |
the impact of local, regional, and national and international economic conditions and events; and
|
• |
the impact of the current
COVID-19
pandemic, the disease caused by the
SARS-CoV-2
|
ITEM 1.
|
Financial Statements
|
December 31,
|
June 30,
|
|||||||
2021
|
2021
|
|||||||
(Unaudited)
|
||||||||
Assets
|
||||||||
Current assets:
|
||||||||
Cash and cash equivalents
|
$ | 12,329 | $ | 19,769 | ||||
Trade and other receivables
|
5 | 25 | ||||||
Prepaid and other assets
|
338 | 814 | ||||||
|
|
|
|
|||||
Total current assets
|
12,672 | 20,608 | ||||||
Property and equipment, net
|
268 | 375 | ||||||
Deposits
|
25 | 9 | ||||||
Other assets
|
161 | 185 | ||||||
Right-of-use
|
888 | 202 | ||||||
|
|
|
|
|||||
Total assets
|
$ | 14,014 | $ | 21,379 | ||||
|
|
|
|
|||||
Liabilities and Stockholders’ Equity
|
||||||||
Current liabilities:
|
||||||||
Trade and other payables
|
$ | 1,946 | $ | 880 | ||||
Accrued employee benefits
|
321 | 276 | ||||||
Lease liabilities, current portion
|
213 | 213 | ||||||
|
|
|
|
|||||
Total current liabilities
|
2,480 | 1,369 | ||||||
Lease liabilities, less current portion
|
698 | — | ||||||
|
|
|
|
|||||
Total liabilities
|
3,178 | 1,369 | ||||||
|
|
|
|
|||||
Commitments and contingencies (Note 1
0
)
|
||||||||
Stockholders’ equity:
|
||||||||
Common stock, $0.0001 par
value-40,000,000
shares authorized; 8,171,690 shares issued and outstanding at December 31, 2021 and June 30, 2021
|
1 | 1 | ||||||
Additional
paid-in
capital
|
152,093 | 151,583 | ||||||
Accumulated deficit
|
(139,985 | ) | (130,119 | ) | ||||
Accumulated other comprehensive loss
|
(1,273 | ) | (1,455 | ) | ||||
|
|
|
|
|||||
Total stockholders’ equity
|
10,836 | 20,010 | ||||||
|
|
|
|
|||||
Total liabilities and stockholders’ equity
|
$ | 14,014 | $ | 21,379 | ||||
|
|
|
|
Three Months Ended
|
Six Months Ended
|
|||||||||||||||
December 31,
|
December 31,
|
|||||||||||||||
2021
|
2020
|
2021
|
2020
|
|||||||||||||
Revenue:
|
||||||||||||||||
Licensing revenues from customers
|
$ | 25 | $ | 1 | $ | 25 | $ | 56 | ||||||||
|
|
|
|
|
|
|
|
|||||||||
Total revenues
|
25 | 1 | 25 | 56 | ||||||||||||
Operating expenses
|
||||||||||||||||
Royalties and license fees
|
— | (19 | ) | — | 114 | |||||||||||
Research and development
|
3,146 | 1,168 | 5,926 | 1,942 | ||||||||||||
General and administrative
|
1,714 | 2,111 | 3,756 | 3,948 | ||||||||||||
|
|
|
|
|
|
|||||||||||
Total operating expenses
|
4,860 | 3,260 | 9,682 | 6,004 | ||||||||||||
|
|
|
|
|
|
|||||||||||
Loss from operations
|
(4,835 | ) | (3,259 | ) | (9,657) | (5,948 | ) | |||||||||
Other income (loss):
|
||||||||||||||||
Foreign currency transaction gain (loss)
|
48 | — | (193 | ) | (54 | ) | ||||||||||
Interest expense, net
|
(11 | ) | (2 | ) | (12) | (3 | ) | |||||||||
Other income, net
|
— | 10 | — | 36 | ||||||||||||
Unrealized loss on investment
|
(23 | ) | (1 | ) | (5) | (1 | ) | |||||||||
|
|
|
|
|
|
|||||||||||
Total other income (loss), net
|
14 | 7 | (210 | ) | (22 | ) | ||||||||||
|
|
|
|
|
|
|||||||||||
Net loss
|
$ | (4,821 | ) | $ | (3,252 | ) | $ | (9,867 | ) | $ | (5,970 | ) | ||||
|
|
|
|
|
|
|||||||||||
Other comprehensive income:
|
||||||||||||||||
Unrealized foreign currency translation
(loss)
gain
|
(57 | ) | 208 | 182 | 386 | |||||||||||
|
|
|
|
|
|
|||||||||||
Total other comprehensive
(loss)
income
|
(57 | ) | 208 | 182 | 386 | |||||||||||
|
|
|
|
|
|
|||||||||||
Total comprehensive loss
|
$ | (4,878 | ) | $ | (3,044 | ) | $ | (9,685 | ) | $ | (5,584 | ) | ||||
|
|
|
|
|
|
|||||||||||
Net loss
|
$ | (4,821 | ) | $ | (3,252 | ) | $ | (9,867 | ) | $ | (5,970 | ) | ||||
|
|
|
|
|
|
|||||||||||
Net loss per share:
|
||||||||||||||||
Basic and diluted
|
$ | (0.59 | ) | $ | (0.76 | ) | $ | (1.21 | ) | $ | (2.21 | ) | ||||
|
|
|
|
|
|
|||||||||||
Weighted average number of shares outstanding: basic and diluted
|
8,171,690 | 4,300,073 | 8,171,690 | 2,704,223 | ||||||||||||
|
|
|
|
|
|
|
|
Common Stock
|
|
|
Additional
Paid-in
Capital |
|
|
Accumulated
Deficit |
|
|
Accumulated
Other Comprehensive Loss |
|
|
Total
Stockholders’ Equity |
|
|||||||||
|
|
Shares
|
|
|
Amount
|
|
||||||||||||||||||
Balance at June 30, 2020
|
1,108,374 | $ | 1 | $ | 128,826 | $ | (116,636 | ) | $ | (1,953 | ) | $ | 10,238 | |||||||||||
Share-based compensation
|
— | — | 38 | — | — | 38 | ||||||||||||||||||
Forfeiture of share-based payments
|
— | — | (14 | ) | 14 | — | — | |||||||||||||||||
Foreign currency translation gain
|
— | — | — | — | 178 | 178 | ||||||||||||||||||
Net loss
|
— | — | — | (2,718 | ) | (2,718 | ) | |||||||||||||||||
|
|
|
|
|
|
|
|
|
|
|
|
|||||||||||||
Balance at September 30, 2020
|
1,108,374 |
|
1 |
|
128,850 |
|
(119,340 | ) |
|
(1,775 | ) |
|
7,736 | |||||||||||
Issuance of common stock and
pre-funded
warrants sold for cash, net of issuance costs of $1,643
|
3,150,514 | 3 | 9,848 | — | — | 9,851 | ||||||||||||||||||
Exercise of
pre-funded
warrants
|
281,581 | — | — | — | — | — | ||||||||||||||||||
Share-based compensation
|
— | — | 82 | — | — | 82 | ||||||||||||||||||
Forfeiture of share-based payments
|
— | — | (385 | ) | 385 | — | — | |||||||||||||||||
Foreign currency translation gain
|
— | — | — | — | 208 | 208 | ||||||||||||||||||
Net loss
|
— | — | — | (3,252 | ) | — | (3,252 | ) | ||||||||||||||||
|
|
|
|
|
|
|
|
|
|
|
|
|||||||||||||
Balance at December 31, 2020
|
4,540,469 | $ | 4 | $ | 138,395 | $ | (122,207 | ) | $ | (1,567 | ) | $ | 14,625 | |||||||||||
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Common Stock
|
|
|
Additional
Paid-in
Capital |
|
|
Accumulated
Deficit |
|
|
Accumulated
Other Comprehensive Loss |
|
|
Total
Stockholders’ Equity |
|
|||||||||
|
|
Shares
|
|
|
Amount
|
|
||||||||||||||||||
Balance at June 30, 2021
|
8,171,690 | $ | 1 | $ | 151,583 | $ | (130,119 | ) | $ | (1,455 | ) | $ | 20,010 | |||||||||||
Share-based compensation
|
— | — | 271 | — | — | 271 | ||||||||||||||||||
Foreign currency translation gain
|
— | — | — | — | 239 | 239 | ||||||||||||||||||
Net loss
|
— | — | — | (5,045 | ) | — | (5,045 | ) | ||||||||||||||||
|
|
|
|
|
|
|
|
|
|
|
|
|||||||||||||
Balance at September 30, 2021
|
8,171,690 |
|
1 |
|
151,854 |
|
(135,164 | ) |
|
(1,216 | ) | 15,475 | ||||||||||||
Share-based compensation
|
— | — | 239 | — | — | 239 | ||||||||||||||||||
Foreign currency translation loss
|
— | — | — | — | (57 | ) | (57 | ) | ||||||||||||||||
Net loss
|
— | — | — | (4,821 | ) | — | (4,821 | ) | ||||||||||||||||
|
|
|
|
|
|
|
|
|
|
|
|
|||||||||||||
Balance at December 31, 2021
|
8,171,690 | $ | 1 | $ | 152,093 | $ | (139,985 | ) | $ | (1,273 | ) | $ | 10,836 | |||||||||||
|
|
|
|
|
|
|
|
|
|
|
|
Six Months Ended
|
||||||||
December 31,
|
||||||||
2021
|
2020
|
|||||||
Cash flows from operating activities:
|
||||||||
Net loss
|
$ | (9,867 | ) | $ | (5,970 | ) | ||
Adjustments to reconcile net loss to net cash used in operating activities:
|
||||||||
Depreciation and amortization
|
107 | 112 | ||||||
Amortization of
right-of-use
|
108 | 95 | ||||||
Unrealized loss on investment
|
5 | 1 | ||||||
Share-based compensation expense
|
510 | 120 | ||||||
Changes in operating assets and liabilities:
|
||||||||
Trade and other receivables
|
— | 28 | ||||||
Other assets
|
470 | 424 | ||||||
Trade and other payables
|
1,146 | (427 | ) | |||||
Accrued employee benefits
|
(5 | ) | 25 | |||||
Lease liabilities
|
(96 | ) | (94 | ) | ||||
|
|
|
|
|||||
Net cash used in operating activities
|
(7,622 | ) | (5,686 | ) | ||||
|
|
|
|
|||||
Cash flows from investing activities:
|
||||||||
Purchases of property and equipment
|
— | (347 | ) | |||||
|
|
|
|
|||||
Net cash used in investing activities
|
— | (347 | ) | |||||
Cash flows from financing activities:
|
||||||||
Proceeds from issues of shares and
pre-funded
warrants
|
— | 11,494 | ||||||
Shares and
pre-funded
warrant issuance costs
|
— | (1,643 | ) | |||||
|
|
|
|
|
|
|
|
|
Net cash provided by financing activities
|
— | 9,851 | ||||||
|
|
|
|
|||||
Effects of exchange rate changes on cash and cash equivalents
|
182 | 391 | ||||||
|
|
|
|
|||||
Net increase (decrease) in cash and cash equivalents
|
(7,440 | ) | 4,209 | |||||
Cash and cash equivalents, beginning of period
|
19,769 | 9,801 | ||||||
|
|
|
|
|||||
Cash and cash equivalents, end of period
|
$ | 12,329 | $ | 14,010 | ||||
|
|
|
|
|||||
Supplemental disclosure of cash flow information:
|
||||||||
Re-measurement
of operating lease
right-of-use
|
$ | 794 | $ | — | ||||
|
|
|
|
Principal place of
business/country of incorporation |
||
Benitec Biopharma Proprietary Limited (“BBL”)
|
Australia | |
Benitec Australia Proprietary Limited
|
Australia | |
Benitec Limited
|
United Kingdom | |
Benitec, Inc.
|
USA | |
Benitec LLC
|
USA | |
RNAi Therapeutics, Inc.
|
USA | |
Tacere Therapeutics, Inc.
|
USA | |
Benitec IP Holdings, Inc.
|
USA |
Level 1: | Observable inputs such as quoted prices (unadjusted) in active markets for identical assets or liabilities. | |
Level 2: | Inputs, other than quoted prices that are observable, either directly or indirectly. These include quoted prices for similar assets or liabilities in active markets and quoted prices for identical or similar assets or liabilities in markets that are not active. | |
Level 3: | Unobservable inputs in which little or no market data exists, therefore developed using estimates and assumptions developed by us, which reflect those that a market participant would use. |
Software |
3-4
years
|
|||
Lab equipment |
3-7
years
|
|||
Computer hardware |
3-5
years
|
|||
Leasehold improvements | shorter of the lease term or estimated useful lives |
(US$’000)
|
December 31,
2021 |
June 30,
2021 |
||||||
Prepaid expenses
|
$ | 472 | $ | 967 | ||||
Security deposit
|
15 | 15 | ||||||
Market value of listed shares
|
12 | 17 | ||||||
|
|
|
|
|||||
Total other assets
|
499 | 999 | ||||||
Less:
non-current
portion
|
(161 | ) | (185 | ) | ||||
|
|
|
|
|||||
Current portion
|
$ | 338 | $ | 814 | ||||
|
|
|
|
(US$’000)
|
December 31,
2021 |
June 30,
2021 |
||||||
Software
|
$ | 14 | $ | 14 | ||||
Lab equipment
|
1,328 | 1,329 | ||||||
Computer hardware
|
26 | 26 | ||||||
Leasehold improvements
|
24 | 24 | ||||||
|
|
|
|
|||||
Total property and equipment, gross
|
1,392 | 1,393 | ||||||
Accumulated depreciation and amortization
|
(1,124 | ) | (1,018 | ) | ||||
|
|
|
|
|||||
Total property and equipment, net
|
$ | 268 | $ | 375 | ||||
|
|
|
|
(US$’000)
|
December 31,
2021 |
June 30,
2021 |
||||||
Trade payable
|
$ | 682 | $ | 274 | ||||
Accrued license fees
|
136 | 140 | ||||||
Accrued professional fees
|
55 | 13 | ||||||
Accrued research and development
|
738 | 279 | ||||||
Accrued bonuses
|
112 | — | ||||||
Other payables
|
223 | 174 | ||||||
|
|
|
|
|||||
Total
|
$ | 1,946 | $ | 880 | ||||
|
|
|
|
(US$’000)
|
Operating
lease
right-of-
use assets |
|||
Balance at July 1, 2021
|
$ | 202 | ||
Re-measurement
during the period
|
794 | |||
Amortization of right of use asset
|
(108 | ) | ||
|
|
|||
Operating lease
right-of-use
|
$ | 888 | ||
|
|
(US$’000)
|
|
Operating
lease liabilities |
|
|
Balance at July 1, 2021
|
$ | 213 | ||
Re-measurement
during the period
|
794 | |||
Principal payments on operating lease liabilities
|
(96 | ) | ||
|
|
|||
Operating lease liabilities at December 31, 2021
|
911 | |||
Less:
non-current
portion
|
(698 | ) | ||
|
|
|||
Current portion at December 31, 2021
|
$ | 213 | ||
|
|
(US$’000)
|
December
31, 2021 |
|||
2022
|
251 | |||
2023
|
290 | |||
2024
|
300 | |||
2025
|
152 | |||
|
|
|||
Total operating lease payments
|
993 | |||
Less imputed interest
|
(82 | ) | ||
|
|
|||
Present value of operating lease liabilities
|
$ | 911 | ||
|
|
Common
Stock from Warrants |
Weighted-
average Exercise Price (per share) |
|||||||
Outstanding at July 1, 2021
|
107,095 | $ | 10.50 | |||||
|
|
|
|
|||||
Outstanding and exercisable at December 31, 2021
|
107,095 | $ | 10.50 |
Stock
Options |
Weighted-
average Exercise Price |
Weighted-
average Remaining Contractual Term |
Aggregate
Intrinsic Value |
|||||||||||||
Outstanding at July 1, 2021
|
702,064 | $ | 7.16 | 8.07 years | $ | — | ||||||||||
|
|
|
|
|||||||||||||
Outstanding at September 30, 2021
|
702,064 |
|
7.16 | 7.82 years | $ | — | ||||||||||
Granted
|
36,000 | 2.99 | 9.93 years | $ | — | |||||||||||
|
|
|
|
|||||||||||||
Outstanding at December 31, 2021
|
738,064 | 6.95 | 7.68 years | $ | — | |||||||||||
Exercisable at December 31, 2021
|
229,333 | $ | 13.59 | 7.20 years | $ | — | ||||||||||
|
|
|
|
Three Months Ended
December 31, |
Six Months Ended
December 31, |
|||||||||||||||
(US$’000) |
2021
|
2020
|
2021
|
2020
|
||||||||||||
Research and development
|
$ | 80 | $ | 6 | $ | 161 | $ | 15 | ||||||||
General and administrative
|
159 | 76 | 349 | 105 | ||||||||||||
|
|
|
|
|
|
|
|
|||||||||
Total share-based compensation expense
|
$ | 239 | $ | 82 | $ | 510 | $ | 120 | ||||||||
|
|
|
|
|
|
|
|
• |
Support the validation and optimization of the newly designed route and method of
BB-301
administration,
|
• |
Confirm the efficiency of vector transduction and transgene expression in the key tissue compartments underlying the natural history of OPMD,
|
• |
Confirm the optimal
BB-301
doses in advance of initiation of human clinical studies,
|
• |
Facilitate the observation of key toxicological data-points.
|
• |
Biologically significant and dose-dependent levels of
BB-301
tissue transduction (i.e., delivery of the multi-functional BB-301 genetic construct into the target pharyngeal muscle cells),
|
• |
Broad-based and dose-dependent expression of the three distinct genes comprising the
BB-301
gene construct within the pharyngeal muscle cells, and
|
• |
Durable, and biologically significant levels of, target gene knock-down (i.e., inhibition of the expression of the gene of interest) within the pharyngeal muscle cells.
|
• |
BB-301
encodes two distinct siRNA species (i.e., siRNA13 and siRNA17) which are each, independently, capable of inhibiting (i.e., “silencing”) the expression of the mutant form of the PABPN1 protein and the wild type (i.e., endogenous) form of the PABPN1 protein (importantly, the mutant form of the PABPN1 protein underlies the development, and progression, of OPMD).
|
• |
BB-301
also codes for a wild type version of the PABPN1 protein whose intracellular expression is unaffected by the inhibitory activities of siRNA13 and siRNA17; this “codon optimized” transcript drives the expression of a PABPN1 protein (i.e., coPABPN1) which serves to replenish the endogenous form of the PABPN1 protein and to replace the mutant form of PABPN1 that underlies the development and progression of OPMD in diseased tissues.
|
• |
For comparative purposes, it should be noted that the average range of expression for wild type PABPN1 within the pharyngeal muscle cells of Beagle dogs is 4.5 copies per
cell-to-7.8
|
• |
As noted above,
BB-301
encodes two distinct siRNA species (i.e. siRNA13 and siRNA17) which are each, independently, capable of inhibiting (i.e., “silencing”) the expression of all forms of the PABPN1 protein (siRNA13 and siRNA17 silence the expression of both wild type PABPN1 [wtPABPN1] and mutant PABPN1).
|
• |
While the Beagle dog subjects treated in the current
BB-301
Pilot Dosing Study do not express mutant PABPN1, the level of
BB-301-driven
|
• |
Thus, the wtPABPN1 silencing activity observed in the current
BB-301
Pilot Dosing Study serves as a surrogate for the silencing activity that would be anticipated in the presence of mutant PABPN1.
|
• |
BB-301
has been evaluated in prior
non-clinical
studies in animals that both express mutant PABPN1 and manifest the key signs and symptoms of OPMD; in the animal model of OPMD (i.e. the A17 mouse model), the achievement of PABPN1 silencing levels of 31% inhibition (or higher) led to resolution of OPMD disease symptoms and the elimination of the histopathological hallmarks of OPMD.
|
• |
The
non-clinical
data derived from the evaluation of
BB-301
in both the murine
proof-of
concept studies and the Pilot Dosing study in Beagle dogs
|
• |
The experimental, analytical, and statistical methods comprising the
12-week
BB-301
GLP Toxicology and Biodistribution study in Beagle dogs
|
• |
The
large-scale
manufacturing plan for clinical grade
BB-301
drug product for use in the Phase 1b/2a clinical study in OPMD patients
|
• |
The design of the Phase 1b/2a clinical study slated for initiation during 2022
|
Three Months Ended
December 31, |
Six Months Ended
December 31, |
|||||||||||||||
2021
|
2020
|
2021
|
2020
|
|||||||||||||
(US$’000)
|
||||||||||||||||
Revenues:
|
||||||||||||||||
Licensing revenues from customers
|
$ | 25 | $ | 1 | $ | 25 | $ | 56 | ||||||||
|
|
|
|
|
|
|
|
|||||||||
Total revenues
|
$ | 25 | $ | 1 | $ | 25 | $ | 56 | ||||||||
|
|
|
|
|
|
|
|
Three Months Ended
December 31, |
Six Months Ended
December 31, |
|||||||||||||||
2021
|
2020
|
2021
|
2020
|
|||||||||||||
(US$’000)
|
||||||||||||||||
Operating Expenses:
|
||||||||||||||||
Royalties and license fees
|
$ | — | $ | (19 | ) | $ | — | $ | 114 | |||||||
Research and development
|
3,146 | 1,168 | 5,926 | 1,942 | ||||||||||||
General and administrative
|
1,714 | 2,111 | 3,756 | 3,948 | ||||||||||||
|
|
|
|
|
|
|
|
|||||||||
Total operating expenses
|
$ | 4,860 | $ | 3,260 | $ | 9,682 | $ | 6,004 | ||||||||
|
|
|
|
|
|
|
|
Three Months Ended
December 31, |
Six Months Ended
December 31, |
|||||||||||||||
2021
|
2020
|
2021
|
2020
|
|||||||||||||
(US$’000)
|
||||||||||||||||
Other Income (Loss):
|
||||||||||||||||
Foreign currency transaction gain (loss)
|
$ | 48 | $ | — | $ | (193 | ) | $ | (54 | ) | ||||||
Interest expense, net
|
(11 | ) | (2 | ) | (12 | ) | (3 | ) | ||||||||
Other income, net
|
— | 10 | — | 36 | ||||||||||||
Unrealized loss on investment
|
(23 | ) | (1 | ) | (5 | ) | (1 | ) | ||||||||
|
|
|
|
|
|
|
|
|||||||||
Total other income (loss), net
|
$ | 14 | $ | 7 | $ | (210 | ) | $ | (22 | ) | ||||||
|
|
|
|
|
|
|
|
Six Months Ended
December 31, |
||||||||
2021
|
2020
|
|||||||
(US$’000)
|
||||||||
Net cash provided by (used in):
|
||||||||
Operating activities
|
$ | (7,622 | ) | $ | (5,686 | ) | ||
Investing activities
|
— | (347 | ) | |||||
Financing activities
|
— | 9,851 | ||||||
Effects of exchange rate changes on cash and cash equivalents
|
182 | 391 | ||||||
|
|
|
|
|||||
Net (decrease) increase in cash
|
$ | (7,440 | ) | $ | 4,209 | |||
|
|
|
|
• |
the timing and costs of our planned clinical trials for our ddRNAi and silence and replace product candidates;
|
• |
the timing and costs of our planned preclinical studies for our ddRNAi and silence and replace product candidates;
|
• |
the number and characteristics of product candidates that we pursue;
|
• |
the outcome, timing and costs of seeking regulatory approvals;
|
• |
revenue received from commercial sales of any of our product candidates that may receive regulatory approval;
|
• |
the terms and timing of any future collaborations, licensing, consulting or other arrangements that we may establish;
|
• |
the amount and timing of any payments we may be required to make, or that we may receive, in connection with the licensing, filing, prosecution, defense and enforcement of any patents or other intellectual property rights;
|
• |
the costs of preparing, filing and prosecuting patent applications, maintaining and protecting our intellectual property rights and defending against intellectual property related claims; and
|
• |
the extent to which we need to
in-license
or acquire other products and technologies.
|
* |
Filed herewith.
|
** |
Furnished, not filed.
|
Benitec Biopharma Inc. | ||||||
Dated: February
14
, 2022
|
||||||
/s/ Jerel Banks
|
||||||
Jerel Banks | ||||||
Executive Chairman and Chief Executive Officer
(principal executive officer)
|
||||||
/s/ Megan Boston
|
||||||
Megan Boston
|
||||||
Executive Director (principal financial and accounting officer) |
1 Year Benitec Biopharma Chart |
1 Month Benitec Biopharma Chart |
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