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Share Name | Share Symbol | Market | Type |
---|---|---|---|
Aprea Therapeutics Inc | NASDAQ:APRE | NASDAQ | Common Stock |
Price Change | % Change | Share Price | Bid Price | Offer Price | High Price | Low Price | Open Price | Shares Traded | Last Trade | |
---|---|---|---|---|---|---|---|---|---|---|
-0.18 | -4.44% | 3.87 | 3.77 | 4.05 | 4.05 | 3.82 | 3.82 | 6,423 | 23:23:53 |
Third quarter 2019 Corporate Update:
APR-246 Update
Earlier this month, the Company announced that it will present updated data from two Phase 1b/2 clinical studies at the 61st American Society of Hematology Annual Meeting (ASH) on December 9, 2019. Data from the U.S. Phase 1b/2 trial and interim results from the French Phase 1b/2 trial of the Company’s lead product candidate APR-246 in combination with Azacitidine (AZA) in patients with TP53 mutant Myelodysplastic Syndromes (MDS) and Acute Myeloid Leukemia (AML) were both chosen for oral presentations at ASH. The titles of the oral presentations are:
The Company will host a Clinical Update Meeting and Webcast on December 9, 2019 at 12:00 PM ET. This Clinical Update meeting will be webcast live and can be accessed from “Events Calendar” in the News and Events section of the Company’s website at https://ir.aprea.com/
Initial Public Offering
On October 7, 2019, Aprea completed its initial public offering (IPO) of 6,516,667 shares of its common stock at a price to the public of $15.00 per share, which included the exercise in full by the underwriters of their option to purchase an additional 850,000 shares of common stock. The Company received gross proceeds, before deducting underwriting discounts and commissions and other offering expenses, of approximately $97.75 million.
Third Quarter Financial Results
About Aprea Therapeutics, Inc.
Aprea Therapeutics, Inc. is a biopharmaceutical company headquartered in Boston, Massachusetts with research facilities in Stockholm, Sweden, focused on developing and commercializing novel cancer therapeutics that reactivate mutant tumor suppressor protein, p53. The Company’s lead product candidate is APR-246, a small molecule in clinical development for hematologic malignancies, including myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML). For more information, please visit the company website at www.aprea.com.
The Company may use, and intends to use, its investor relations website at www.ir.aprea.com as a means of disclosing material nonpublic information and for complying with its disclosure obligations under Regulation FD.
Forward-Looking Statement Certain information contained in this press release includes “forward-looking statements”, within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended, related to our clinical trials, regulatory submissions and projected cash position. We may, in some cases use terms such as “predicts,” “believes,” “potential,” “continue,” “anticipates,” “estimates,” “expects,” “plans,” “intends,” “may,” “could,” “might,” “likely,” “will,” “should” or other words that convey uncertainty of the future events or outcomes to identify these forward-looking statements. Our forward-looking statements are based on current beliefs and expectations of our management team that involve risks, potential changes in circumstances, assumptions, and uncertainties. Any or all of the forward-looking statements may turn out to be wrong or be affected by inaccurate assumptions we might make or by known or unknown risks and uncertainties. These forward looking statements are subject to risks and uncertainties including risks related to the success and timing of our clinical trials or other studies and the other risks set forth in our filings with the U.S. Securities and Exchange Commission, including our Registration Statement on Form S-1 (File No. 333-233662) and our Quarterly Report on Form 10-Q. For all these reasons, actual results and developments could be materially different from those expressed in or implied by our forward-looking statements. You are cautioned not to place undue reliance on these forward-looking statements, which are made only as of the date of this press release. We undertake no obligation to publicly update such forward-looking statements to reflect subsequent events or circumstances.
Source: Aprea Therapeutics
Corporate Contacts:
Scott M. CoianteSr. Vice President and Chief Financial Officer617-463-9385
Gregory A. KorbelVice President of Business Development617-463-9385
Aprea Therapeutics, Inc.Condensed Consolidated Balance Sheets(Unaudited)
September 30,2019 | December 31,2018 | ||||||
Assets | |||||||
Current assets: | |||||||
Cash and cash equivalents | $ | 52,334,102 | $ | 65,675,931 | |||
Deferred offering cost | 4,070,690 | — | |||||
Prepaid expenses and other current assets | 339,814 | 322,146 | |||||
Total current assets | 56,744,606 | 65,998,077 | |||||
Property and equipment, net | 31,032 | 24,450 | |||||
Right of use lease asset | 560,318 | — | |||||
Other noncurrent assets | 102 | 111 | |||||
Total assets | $ | 57,336,058 | $ | 66,022,638 | |||
Liabilities, Convertible Preferred Stock and Stockholders’ Deficit | |||||||
Current liabilities: | |||||||
Accounts payable | $ | 3,510,105 | $ | 1,739,337 | |||
Accrued expenses | 5,847,364 | 3,128,772 | |||||
Lease liability—current | 226,852 | — | |||||
Total current liabilities | 9,584,321 | 4,868,109 | |||||
Lease liability—noncurrent | 358,404 | — | |||||
Total liabilities | 9,942,725 | 4,868,109 | |||||
Commitments and contingencies | |||||||
Convertible preferred stock: | |||||||
Series A convertible preferred stock, $0.001 par value; 612,446 shares issued and outstanding at September 30, 2019 and December 31, 2018 (liquidation preference of $6,483,044 at September 30, 2019) | 6,483,044 | 6,483,044 | |||||
Series B convertible preferred stock, $0.001 par value; 7,235,969 shares issued and outstanding at September 30, 2019 and December 31, 2018 (liquidation preference of $62,288,856 at September 30, 2019) | 49,742,942 | 49,742,942 | |||||
Series C convertible preferred stock, $0.001 par value; 5,179,877 and 4,712,698 shares issued and outstanding at September 30, 2019 and December 31, 2018, respectively (liquidation preference of $66,451,815 at September 30, 2019) | 61,963,007 | 56,364,645 | |||||
Total convertible preferred stock | 118,188,993 | 112,590,631 | |||||
Stockholders’ equity (deficit): | |||||||
Common stock, par value $0.001 at September 30, 2019 and $0.11 at December 31, 2018; 1,181,733 and 1,155,366, shares issued and outstanding at September 30, 2019 and December 31, 2018, respectively | 1,182 | 127,091 | |||||
Additional paid‑in capital | 20,346,849 | 19,666,588 | |||||
Accumulated other comprehensive loss | (13,688,166 | ) | (8,761,325 | ) | |||
Accumulated deficit | (77,455,525 | ) | (62,468,456 | ) | |||
Total stockholders’ deficit | (70,795,660 | ) | (51,436,102 | ) | |||
Total liabilities, convertible preferred stock and stockholders’ deficit | $ | 57,336,058 | $ | 66,022,638 | |||
Aprea Therapeutics, Inc.Condensed Consolidated Statements of Operations and Comprehensive Loss(Unaudited)
Three Months Ended September 30, | Nine Months Ended September 30, | ||||||||||||||||
2019 | 2018 | 2019 | 2018 | ||||||||||||||
Operating expenses: | |||||||||||||||||
Research and development | $ | 4,910,409 | $ | 2,307,022 | $ | 12,908,679 | $ | 9,799,811 | |||||||||
General and administrative | 2,307,946 | 623,702 | 4,655,861 | 1,790,222 | |||||||||||||
Total operating expenses | 7,218,355 | 2,930,724 | 17,564,540 | 11,590,033 | |||||||||||||
Other income (expense): | |||||||||||||||||
Interest expense | (6,098 | ) | 4 | (13,537 | ) | (184 | ) | ||||||||||
Foreign currency gain (loss) | 975,034 | (207,542 | ) | 2,591,008 | 741,616 | ||||||||||||
Total other income (expense) | 968,936 | (207,538 | ) | 2,577,471 | 741,432 | ||||||||||||
Net loss | $ | (6,249,419 | ) | $ | (3,138,262 | ) | $ | (14,987,069 | ) | $ | (10,848,601 | ) | |||||
Other comprehensive loss: | |||||||||||||||||
Foreign currency translation | (2,940,174 | ) | 65,800 | (4,926,841 | ) | (1,110,408 | ) | ||||||||||
Total comprehensive loss | (9,189,593 | ) | (3,072,462 | ) | (19,913,910 | ) | (11,959,009 | ) | |||||||||
Net loss per share attributable to common stockholders, basic and diluted | $ | (5.29 | ) | $ | (2.72 | ) | $ | (12.72 | ) | $ | (9.40 | ) | |||||
Weighted average basic and diluted shares of common stock outstanding | 1,181,726 | 1,154,573 | 1,178,206 | 1,154,264 |
1 Year Aprea Therapeutics Chart |
1 Month Aprea Therapeutics Chart |
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