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AMGN Amgen Inc

299.755
-11.54 (-3.71%)
Last Updated: 18:52:04
Delayed by 15 minutes
Share Name Share Symbol Market Type
Amgen Inc NASDAQ:AMGN NASDAQ Common Stock
  Price Change % Change Share Price Bid Price Offer Price High Price Low Price Open Price Shares Traded Last Trade
  -11.54 -3.71% 299.755 299.70 299.89 312.73 297.52 310.88 2,655,120 18:52:04

Amgen Says Cholesterol Drug Study Meets Primary Endpoint

17/03/2014 2:14pm

Dow Jones News


Amgen (NASDAQ:AMGN)
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By Nicholas Hatcher

Amgen Inc. (AMGN) said its Phase 3 trial studying its Evolocumab cholesterol drug met its primary endpoint of the reduction in LDL-C, or "bad" cholesterol.

The Thousand Oaks, Calif., pharmaceutical company said its TESLA trial of Evolocumab "in patients with homozygous familial hypercholesterolemia, a rare and serious disease" demonstrated positive top-line results.

Safety was generally balanced across treatment groups, the company said, and the most common adverse events were upper respiratory tract infection, influenza, gastroenteritis and nasopharyngitis.

Evolocumab is an investigational fully human monoclonal antibody that inhibits a protein that reduces the liver's ability to remove bad cholesterol from the blood.

Write to Nicholas Hatcher at nicholas.hatcher@wsj.com

Subscribe to WSJ: http://online.wsj.com?mod=djnwires


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