Holding(s) in Company

RNS Number:5119P
Cambridge Antibody Tech Group PLC
08 September 2003

                                  SCHEDULE 10

                   NOTIFICATION OF MAJOR INTERESTS IN SHARES


1)   Name of company
Cambridge Antibody Technology


2)   Name of shareholder having a major interest
Finsbury Worldwide Pharmaceutical Trust Plc


3)   Please state whether notification indicates that it is in respect of
     holding of the shareholder named in 2 above or in respect of a
     non-beneficial interest or in the case of an individual holder if it is a
     holding of that person's spouse or children under the age of 18
Not disclosed


4)   Name of the registered holder(s) and, if more than one holder, the
     number of shares held by each of them
As in 2 above

5)   Number of shares/amount of stock acquired
100,000


6)   Percentage of issued class
0.27%


7)   Number of shares/amount of stock disposed
NIL


8)   Percentage of issued class
N/A


9)   Class of security
Ordinary 10p shares


10)  Date of transaction
4 September 2003


11)  Date company informed
5 September 2003


12)  Total holding following this notification
1,100,000



13)  Total percentage holding of issued class following this notification
3.01%


14)  Any additional information



15)  Name of contact and telephone number for queries
Diane Mellett 01223 471471


16)  Name and signature of authorised company official responsible for
     making this notification
Diane Mellett, Company Secretary

     Date of notification 8 September 2003







                                  SCHEDULE 10

                   NOTIFICATION OF MAJOR INTERESTS IN SHARES


1)   Name of company
Cambridge Antibody Technology


2)   Name of shareholder having a major interest
OrbiMed Advisors LLC and Samuel D. Isaly


3)   Please state whether notification indicates that it is in respect of
     holding of the shareholder named in 2 above or in respect of a
     non-beneficial interest or in the case of an individual holder if it is a
     holding of that person's spouse or children under the age of 18
Non Beneficial


4)   Name of the registered holder(s) and, if more than one holder, the
     number of shares held by each of them
As in 2 above

5)   Number of shares/amount of stock acquired
100,000

6)   Percentage of issued class
0.27%

7)   Number of shares/amount of stock disposed
NIL


8)   Percentage of issued class
N/A


9)   Class of security
Ordinary 10p shares


10)  Date of transaction
4 September 2003


11)  Date company informed
8 September 2003


12)  Total holding following this notification
2,752,700 of which 341,900 are held in the form of American Depository Receipts


13)  Total percentage holding of issued class following this notification
7.53%

14)  Any additional information
The figure disclosed in 12 above includes 1,100,000 shares held by Finsbury
Worldwide Pharmaceutical Trust Plc and notified separately by the Company.


15)  Name of contact and telephone number for queries
Diane Mellett 01223 471471


16)  Name and signature of authorised company official responsible for
     making this notification
Diane Mellett, Company Secretary

     Date of notification 8 September 2003



                      This information is provided by RNS
            The company news service from the London Stock Exchange
END

HOLEALNPESFDEFE