Holding(s) in Company

RNS Number:6947T
iSoft Group PLC
29 December 2003



LETTER TO: ISOFT GROUP PLC
DATED:     23 DECEMBER 2003

Companies Act 1985 ("The Act") - Part VI

I hereby inform you that as at 22 December 2003 Barclays PLC, through the legal 
entities listed on the the below schedule, has a notifiable interest in the 
capital of your Company of 5.25%.

Details of this interest, together with a breakdown between registered holders 
(as required by Section 202(3) of the Act), are below.

The issued capital of 123,611,019 is the latest figure available to us.  if this 
is incorrect please let me know.

If you have any questions arising from this letter, please contact me 
on 020 7699 2305.

FROM:  GEOFF SMITH
       MANAGER, SECRETARIAL SERVICES
       BARCLAYS


                               LEGAL ENTITY REPORT

                                   ISOFT GROUP

As at 22 December 2003 Barclays PLC, through the legal entities listed below,
had a notifiable interest in 6,493,236 ORD GBP0.10 representing 5.25% of the 
issued share capital of 123,611,019 units.

Legal Entity                                   Holding          Percentage Held

Barclays Life Assurance Co Ltd                 273,272                   0.2211
Barclays Global Investors Ltd                4,735,376                   3.8309
Barclays Global Investors, N.A.              1,449,549                   1.1727
Barclays global Investors Australia Ltd         35,039                   0.0283

                          Group Holding      6,493,236                   5.2530



                           REGISTERED HOLDERS REPORT

ISOFT GROUP                                                       SEDOL: 0916561

As at 22 December 2003 Barclays PLC, through the registered holders listed 
below, had a notifiable interest in 6,493,236 ORD GBP0.10 representing 5.25% of 
the issued share capital of 123,611,019 units.

Registered Holder                         Account Designation               Holding

ALMLUFTTL - 18409 - CHASE MANHATTA             ALMLUFTT                      32,616
ALSMOTTL - 16482 - CHASE MANHATTA              ALSMCOTT                     499,416
ASTEXMTTL - 21359 - CHASE NOMINEES             ASTEXMTT                      92,910
ASTUKCTTL - 16480 - CHASE MANHATTA             ASTUKCTT                     379,746
ASUKEXTTL - 20947 - CHASE MANHATTA             ASUKEXTT                   3,259,417
BLENTPUKQ - 16345 - CHASE MANHATTA             BLENTPUK                      50,021
BLEQPCUKQ - 16331 - CHASE MANHATTA             BLEOFDUK                      25,668
BLEQPTUEA - 16341 - CHASE MANHATTA             BLEOPTUE                     133,876
BLEQPTUEQ - 16341 - CHASE MANHATTA             BLEOPTUK                      63,707
BLUNKINTTL - 16400 - CHASE MANHATTA            BLUKINTT                     424,302
CHATRKTTL - 16376 - CHASE MANHATTA             CHATRKTT                      46,969
INVESTORS BANK AND TRUST CO.                   5527191                      949,996
INVESTORS BANK AND TRUST CO.                   536747                       221,871
INVESTORS BANK AND TRUST CO.                   552942                        53,099
INVESTORS BANK AND TRUST CO.                   595966                        83,705
JP MORGAN CHASE BANK                           540186                        35,039
NORTHERN TRUST BANK - BGI SEPA                 581610                        86,018
NORTHERN TRUST BANK - BGI SEPA                 584069                        36,117
UBS Limited                                    583996                        18,743

                                                             Total        6,493,236


                      This information is provided by RNS
            The company news service from the London Stock Exchange

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