Blocklisting Interim Review

RNS Number:9750K
Alizyme PLC
12 May 2003

                                   SCHEDULE 5

                        BLOCKLISTING SIX MONTHLY RETURN



1. Name of company


Alizyme plc



2. Name of scheme


Alizyme plc Share Option Scheme



3. Period of return:


From       10 November 2002                              To     9 May 2003



4. Number and class of shares(s) (amount of stock / debt security) not issued
under scheme


220,000



5. Number of shares issued / allotted under scheme during period:


NIL



6. Balance under scheme not yet issued / allotted at end of period


220,000



7. Number and class of share(s) (amount of stock / debt securities) originally
listed and the date of admission;


78,827,444 ordinary shares of 2p each fully paid. Admitted on 19 October 2000



Please confirm total number of shares in issue at the end of the period in order
for us to update our records


136,896,943



Contact for queries


Name              David Campbell

Address           Granta Park, Great Abington, Cambridge CB1 6GX

Telephone         [phone]






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