Share Purchase Plan

RNS Number:4177Q
Skyepharma PLC
01 October 2003


1 October 2003

Immediate Release


                         SkyePharma PLC ("the Company")

As a result of transactions on 30 September 2003 by the SkyePharma PLC Share
Purchase Plan (an Inland Revenue approved all employee share purchase plan),
Michael Ashton and Donald Nicholson, directors of the Company, as trustees of
the Plan, became the beneficial owners of an additional 5,612 Ordinary Shares of
the Company, bringing the total held by the Plan to 83,246 Ordinary Shares of
the Company.

As a result the executive directors of the Company have the following additional
interests as a result of their personal participation in the Plan:-


                                     Partnership                   Matching                Total number of
                                Shares purchased             Shares awarded                Partnership and
                            on 30 September 2003            on 30 September           Matching Shares held
                                    at #0.58 per              2003 at #0.58          on 30 September 2003.
                                           share                  per share


Ian Gowrie-Smith                              215                        215                         3,564
Michael Ashton                                216                        216                         8,994
Donald Nicholson                              216                        216                         8,994





In accordance with the rules of the Plan these directors have been awarded the
Matching Shares on the basis of one Matching Share for each Partnership Share.

The beneficial ownership of the Matching Shares will pass to the directors in
three years time subject to continued employment and the retention of the
underlying Partnership Shares.


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