Share Purchase Plan

RNS Number:7956L
Skyepharma PLC
02 June 2003


Immediate Release                                                 02 June 2003


                         SkyePharma PLC ("the Company")


As a result of transactions on 30 May 2003 by the SkyePharma PLC Share
Purchase Plan (an Inland Revenue approved all employee share purchase plan),
Michael Ashton and Donald Nicholson, directors of the Company, as trustees of
the Plan, became the beneficial owners of an additional 6,120 Ordinary Shares of
the Company, bringing the total held by the Plan to 62,904 Ordinary Shares of
the Company.

As a result the executive directors of the Company have the following additional
interests as a result of their personal participation in the Plan:-



                      Partnership         Matching
                      Shares purchased    Shares awarded        Total number of
                      on 30 May 2003      on 30 May             Partnership and
                      at 52.5 pence per   2003 at 52.5     Matching Shares held
                      share.              pence per share.      on 30 May 2003.

Ian Gowrie-Smith         238                238                  2,020
Michael Ashton           238                238                  7,450
Donald Nicholson         238                238                  7,450


In accordance with the rules of the Plan these directors have been awarded the
Matching Shares on the basis of one Matching Share for each Partnership Share.


The beneficial ownership of the Matching Shares will pass to the directors in
three years time subject to continued employment and the retention of the
underlying Partnership Shares.


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